5,359 research outputs found
Ritmi circadiani ormonali in pazienti con sinndrome ossessivo-compulsiva prima e dopo trattamento con fluoxetina
No full textCorrelati neuroendocrini della sindrome ossessivo-compulsiva: implicazioni per il trattamento
No full textShort interval intracortical facilitation correlates with the degree of disability in multiple sclerosis
No full textMori F, Kusayanagi H, Monteleone F, et al. Short interval intracortical facilitation correlates with the degree of disability in multiple sclerosis. Brain Stimulation. 2013;6(1):67-71
Attachment style and cortisol response to psychosocial stress in eating disorder patients
No full textTh17-related cytokines: new players in the control of chronic intestinal inflammation
No full textAbstract Crohn's disease (CD) and ulcerative colitis (UC), the main forms of inflammatory bowel diseases (IBD) in man, are thought to be caused by an excessive and poorly controlled immune response that is directed against components of the normal microflora. The exact sequence of events by which this pathological process is triggered and maintained is not fully understood, but studies in experimental models of IBD and data emerging from recent clinical trials indicate that T cell-derived cytokines are crucial mediators of the tissue damage. Although CD and UC have been traditionally considered two typical examples of T helper (Th)1 or Th2-associated disease respectively, it is now known that CD- and UC-related inflammation is also marked by enhanced production of cytokines made by a distinct subset of Th cells, termed Th17 cells. Th17 cytokines can have both tissue-protective and inflammatory effects in the gut and there is evidence that Th17 cells can alter their cytokine program according to the stimuli received and convert into Th1-producing cells. These novel findings have contributed to advancing our understanding of mechanisms of gut tissue damage and open new avenues for development of therapeutic strategies in IBD.</p
Parole composte e modalità di recupero automatico delle informazioni
No full textIn queste pagine ci occuperemo principalmente delle parole composte dell’italiano, del ruolo che esse svolgono all’interno della terminologia della nostra lingua e dei formalismi utilizzati per la loro descrizione linguistico-computazionale. Vedremo inoltre come il recupero automatico delle informazioni basato sulle parole composte sia non solo possibile, ma anche importante per ciò che riguarda la lettura e la “comprensione” automatica dei testi tramite computer. Per portare a termine questo percorso, daremo delle parole composte una definizione basata su livelli diversi dell’analisi linguistica, ma che tenderà a prediligere gli aspetti formali (leggi morfologici), le caratteristiche lessicali e il valore sintattico dei composti. A tale scopo, inquadreremo la nostra analisi nell’ambito dei formalismi definiti da (Harris 1970) e (Gross 1977), e per quanto riguarda quest’ultimo tenendo soprattutto in considerazione il metodo investigativo lessico-grammaticale, da lui elaborato per il francese e sviluppato per l’italiano da (Elia, Martinelli, D’Agostino 1981).
Questo articolo rappresenta il contributo al PRIN ALTI (Atlanti Linguistici Tematici Informatici) elaborato sotto la guida di Annibale Elia dall’unità di ricerca del Dipartimento di Scienze della Comunicazione dell’Università degli Studi di Salerno. Il programma ALTI si pone come obbiettivo fondante la costituzione di atlanti lessicali ipertestuali e multimediali, che funzionino come peculiari mappe cognitive degli ambiti tematici indagati
Childhood maltreatment is associated with cortical thinning in people with eating disorders
No full textChildhood maltreatment (CM) is a non-specific risk factor for eating disorders (ED) and is associated with a greater severity in their clinical presentation and poorer treatment outcome. These data suggest that maltreated people with ED may be biologically other than clinically different from non-maltreated people. The aim of the present study was to investigate cortical thickness (CT), a possible biomarker of neurodevelopment, in people with ED with or without history of CM and in healthy women. Twenty-four healthy women, 26 with anorexia nervosa and 24 with bulimia nervosa underwent a 3T MRI scan. All participants filled in the childhood trauma questionnaire. All neuroimaging data were processed by FreeSurfer. Twenty-four participants with ED were identified as maltreated and 26 participants with ED as non-maltreated. All healthy women were non-maltreated. Compared to healthy women, maltreated people with ED showed lower CT in the left rostral anterior cingulate gyrus, while compared to people with ED without history of CM showed lower CT values in the left superior frontal and in right caudal middle frontal and superior parietal gyri. No significant differences emerged in CT measures between healthy women and people with ED without history of CM. The present findings show for the first time that in adult people with ED childhood maltreatment is associated with cortical thinning in areas implicated in the modulation of brain processes that are acknowledged to play a role in the psychopathology of ED
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