1,721,156 research outputs found
Non-Destructive Testing of Brazed Graphite/Molybdenum Joints by Radiographic Examination
No full text
Immunochemical investigation of CYP 1A and Mn-SOD in Scapharca inaequivalvis exposed to benzo[a]pyrene
No full textBenzo[a]pyrene among PAHs is the most pollutant investigated for its toxicity and carcinogenicity.
In vertebrates, the CYP1A subfamily members represent the main forms of P450 associated
with exposures to PAHs and the P450 dependent oxidative metabolism of B[a]P leads to the production
of ROS (mostly O2
-). About this, SOD represents an appropriate response to oxidative
injury as a mechanism of protection against increasing ROS levels. This research was focused on the
study of the induction of CYP 1A and Mn-SOD, involved in detoxification processes, in hepatopancreas
of Scapharca inaequivalvis (Adriatic bivalve) exposed to B[a]P. Scapharca specimens were
exposed to 0.44 mg B[a]P. Samples were taken at 0 (control), 12, 24, 36 h of exposure. The B[a]P
concentration were analyzed in samples in soft tissues of pooled animals by HPLC. CYP 1A1 and
Mn-SOD, were detected in hepatopancreas, by western blot analysis after SDS-PAGE. Immunopositive
bands were semi-quantified by Quantity One Software. B[a]P content showed rapid increase
(12 h) followed by a similar rapid decrease. CYP 1A (49 kDa) showed major levels after 36 h of
B[a]P exposure. The Mn-SOD imunopositive band (26 kDa) were less significantly expressed after 36
h of exposure only with respect to the control group. In conclusion the increase of CYP 1A levels
in Scapharca suggests an active biotrasformation mechanism due to the MFO system. The decrease
in Mn-SOD expression might be associated with the disease processes. The induction of CYP 1A in
presence of B[a]P might be a reliable and sensitive biomarker of PAH exposure in aquatic organisms.
(Supported by MIPAF contr. No. 6C66)
Phagocyti
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Studio di validazione di una scala per la rilevazione della disposizione del paziente nei confronti del ricovero e del trattamento in ambiente psichiatrico: risultati preliminari
No full textInstitutional therapeutic alliance and its relationship with outcomes in a psychiatric day hospital program
No full textVariations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
State and parameter estimation approach to monitoring AGR nuclear core
No full textThis work concerns with the problem of monitoring an Advanced Gas-cooled Nuclear Reactor (AGR) core. This plant (figure 1) makes use of the heat given by the nuclear efficient reaction to produce electricity by means of steam turbines. These are driven by steam, which is heated, from the AGR gas using a heat exchanger. One of the advantages of a gas cooled reactor is the high temperature that the gas can achieve so that when it is used in conjunction with the heat exchanger and steamed turbine the thermal efficiency is very high
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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