1,720,998 research outputs found
Re: transrectal ultrasound-guided biopsy of the prostate: aspirin increases the incidence of minor bleeding complications.
Orgasm associated incontinence (climacturia) in bladder-neck sparing radical prostatectomy: clinical and video-urodynamic evaluation
Re: Indwelling ureteral stents and sexual health: a prospective, multivariate analysis. M. C. Sighinolfi, S. Micali, S. De Stefani, A. Mofferdin, M. Grande, M. Giacometti, N. Ferrari, M. Rivalta and G. Bianchi. J Urol 2007; 178: 229-231.
Re: indwelling ureteral stents and sexual health: a prospective multivariate analysis . MC Sighinolfi et al. J.Urol 2007, 178 229-31
We read with interest the article by Sighinolfi et al. who prospectively assessed the impact of indwelling ureteral stents on sexual function using the IIEF-5 and Female SFI. At 45 and 60 days after stent insertion 83% of men reported some grade of sexual dysfunction, and 30% of women reported no sexual activity due to stent related anxiety.
In recent years there has been an increasing awareness of the need for validated tools to measure objectively the considerable morbidity associated with ureteral stenting, and to address its influence on daily activities. These tools have remained elusive. In this respect the present study significantly adds to the existing literature. Nevertheless we would like to address some issues that we believe deserve scrutiny.
Although the authors recognize the robustness of the USSQ developed by Joshi et al. they failed to use it in their study. The USSQ is a validated self-administered instrument with good evaluative and discriminant properties, which explores stent related morbility in 6 areas. The questionnaire has been adopted in several clinical trials and has recently been validated by our group in Italian in a prospective cohort of 66 patients of box sexes with indwelling stents.
In the USSQ sexual function for both sexes is investigated with 3 questions evaluating transient but complete sexual dysfunction , pain during intercourse and overall satisfaction for those subjects with a pre-stent active sex life.
The 2 specific questionnaires on sexual dysfunction were chosen by Sighinolfi et al. for a more thorough assessment. However one has to recognize that they have not been formally validated in Italian and thus a bias may have been introduced. Moreover with the IEEF-5 the evaluation of pain during intercourse, commonly reported complaint (64% and 45% of men at 1 and 4 weeks after stent insertion, respectively in our series) remains unexplored.
Finally a single multidimensional questionnaire with a separate index score for each domain such as the USSQ, would have allowed an easier and more reliable correlation between sexual dysfunction and all other symptoms.
Within the same cohort used for our validation study we perform a multivariate analysis to identify predictors of stent related morbidity, including patient age, gender and BMI and stent length, size and location of distal extremity with respect to the midline has determined on abdominal X-ray. Stent distal loop crossing the midline, which was previously shown to impact symptoms negatively , proved to be an independent predictor of morbidity for all USSQ domains including sexual matters. In particular 82% and 100% of original active male and female patients with this condition, respectively reported impaired sexual function at 1 week, compared to 43%and 80% respectively with the stent not crossing the midline (p<0,01).
This easily determinable parameter was not investigated by the authors
Re: A randomized controlled trial of topical glyceryl trinitrate before transrectal ultrasonography-guided biopsy of the prostate
No abstract is available for this article
Perianal and intrarectal anaesthesia for transrectal biopsy of the prostate: a prospective randomized study comparing lidocaine-prilocaine cream and placebo
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Orgasm-associated incontinence (climacturia) after bladder neck-sparing radical prostatectomy: clinical and video-urodynamic evaluation
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