1,720,959 research outputs found
Evidence that natural benzodiazepine-like compounds increase during spontaneous labour
No full textNatural benzodiazepine-like compounds (NBDZ) are present in the blood of normal people free of commercial benzodiazepine medication. In this work, we evaluated the Levels of NBDZ in maternal/foetal serum during delivery after spontaneous tabour (VD) or caesarean section (CS). For both the VD (n=11) and the CS (n=11) groups (VD+CS=22), three blood samples were collected at three different times: the first was collected three days before tabour, the second immediately after delivery or at fetal abdominal extraction and the third one was obtained at second day post-partum. NBDZ were measured by radioreceptor binding assay after HPLC extraction and purification white cortisol was measured through radioimmunoassay. In the VD group, a significant increase of NBDZ levels occurred at tabour in comparison with the levels found in pre- and post-partum periods. By the contrary, no differences in NBDZ Levels were found in the CS group at the three different times. The levels of cortisol in the VD group were found to be higher at tabour than that determined at pre- and post-partum. Again no significant changes were found in the CS group. These findings suggest for the first time that tabour is associated with a marked increase of NBDZ which could be envisaged as a stress-retated event
ORANGE: Outcome-Oriented Predictive Process Monitoring Based on Image Encoding and CNNs
Full text linkThe outcome-oriented predictive process monitoring is a family of predictive process mining techniques that have witnessed rapid development and increasing adoption in the past few years. Boosted by the recent successful applications of deep learning in predictive process mining, we propose ORANGE, a novel deep learning method for learning outcome-oriented predictive process models. The main innovation of this study is that we adopt an imagery representation of the ongoing traces, which delineates potential data patterns that arise at neighbour pixels. Leveraging a collection of images representing ongoing traces, we train a Convolutional Neural Network (CNN) to predict the outcome of an ongoing trace. The empirical study shows the feasibility of the proposed method by investigating its accuracy on different benchmark outcome prediction problems in comparison to state-of-art competitor methods. In addition, we show how ORANGE can be integrated as an Intelligent Assistant into a CVM realized by MTM Project srl company to support sales agents in their negotiations. This case study shows that ORANGE can be effectively used to smartly monitor the outcome of ongoing negotiations by early highlighting negotiations that are candidate to be completed successfully
Evidence that endogenous benzdiazepine-like compounds increase during spontaneous delivery
No full textIt has been established that endogenous benzodiazepines (EBDZ) play a role in the pathogenesis of different pathologies like hepatic encephalopathy or idiopathic recurring stupor(1-2). Evidences have not been provided about the role of EBDZ during pregnancy and delivery. In this work we evaluated a possible changes of EBDZ in maternal/foetal serum during delivery after spontaneous labour (VD) or caesarean section (CS). For both VD and CS groups (n=24) 3 blood samples were collected at 3 different times: the first was collected at least 3 days before labour and delivery, the second was collected at the moment of the delivery or at foetal abdominal extraction; the third sample was obtained at 2nd day post-partum. Determination of EBDZ was performed as already described (1) and cortisol was measured through commercially available radioimmunoassay kit. For the statistical analysis of EBDZ Wilcoxon test was used for within-subjects comparison and Mann-Whitney tests for between subjects comparison. For the statistical analysis of cortisol levels the analysis of variance and paired t-test was used. In the VD group a significant increase of EBDZ occurred at delivery respect with both baseline (P=0.008) and postpartum (P=0.028) values. Interestingly in CS group were found no differences in the 3 different analysed samples. The cortisol levels in VD group at delivery (560 ± 156 ng/ml) were found to be higher than that at baseline (252 ± 93, t= 5.47, P<0.0001) and post-partum (241 ± 44, t=6.11, P<0.0001) while in CS group no significant changes were found. These findings demonstrated for the first time that parturition is associated with a marked increase of EBDZ which could be attributed to stress present at delivery time
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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