1,721,070 research outputs found
Diagnosis prognosis and therapy of phyllodes tumor of the breast
No full textThe authors report 4 cases very interesting for the differentil diagnosis of philloides tumor, a brest tumor with a mainly local malignant potential.
Such tumors althrough presenting histologic clinical and instrumental features which allow for a presumtive pre-surgical diagnosis often has characteristics comparable to other breast pathologies with a different natural history.
the authors after analyzing clinical mammographic echographic and histological features of the tumorsuggest the most appropriate therapy for the local control of the lesions. Surgical excission shoud be carried at least one centimeter deep into the normal tissueto prevent local relapse related to an incomplete enucleation. Infact the tumor is only apparently capsulated .An adequate clinical and instrumental follow-up for the early diagnosis of the early occurrent relapse is mandatory
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Attualità e prospettive nella diagnosi precoce della poliposi diffusa familiare.
No full textOur own study consider the primary
importance of prophylactic surgical
therapy in subjects affected by "Diffuse
Familiar Polyposis" for possibility
of cancerizzation in patients 39 -
40 years old.
We think this "prophylactic therapy"
resulting by a manifold work that
assure a premature diagnosis and a decrease
of malignant index in this pathology
[Diagnostic use of the cell culture technique in a case of postoperative saccate lymphorrhea].
No full textThe Authors demonstrated the presence of tumour cells by an in vitro culture of the cells from the pellet of a postoperative saccate effusion, when no tumor cells were evident by the cytologic examination of the effusion. The ultrastructural features and the immunocytochemical characteristics of the cell line were analyzed and these data confirmed its malignant nature. It allowed a firm diagnosis, a correct therapy and prognosis
Sulla prevenzione del cancro colorettale.
No full textThe aim of our study is to investigate
groups of patients affected by large
bowel adenomatosis and groups of
asymtomatic subjects to make a mass
screening. Looking at this purpouse
we consider two different groups of
subjects: the first constituted by "high
risk" and symptomatic patients,
the second constituted by asimptomatic
subjects, The study also show
the way for a correct methodology
and diagnostic "iter" in this pathology.
We also consider the possibility of
a "mass spreading" of the problem and its implication
Il significato della componente villosa negli adenomi del colon
No full textThe present study analyzes our own experience with 337 colonie adenomas
and elucidates the relationship between the villous component of polyps and
their chances of being malignant. Our study has shown an increased de' incidence
of severe dysplasia and carcinoma in the presence cf papillary [eatiires. the frequency
with which a villous growth pattern is [oundincreases with the size oJ the
polyps and age the patients. From our review, ttuo-thirds of adenomas removed
[romrhe large intestine are not purely adenomatous and shoui a varied percentage
of villous component. Our classification poys strict attention to histologic growth
pattern
HTLV-I AND HIV-1 INFECTION IN PATIENTS WITH LYMPHADENOPATHY SYNDROME DETECTED DURING ROUTINE BREAST SCREENING AT A TUMOR PREVENTION CENTER
No full textLymphadenopathy with no apparent cause had been reported in a group of women participating in a mammary tumor prevention program. A screening for retrovirus infection was organized to detect the virus as possible etiological agents. Data show a high percentage of positivity for HIV-1 among these lymphadenopathy patients, and surprisingly for HTLV-I, while no such positivity for either virus was found in matched controls or in patients where a different causal agent for lymphadenopathy was found. Of 26 seropositives, 23 deny any risk factor for HIV-1 and do not come from a HTLV-I known endemic area, but while it is impossible to exclude their knowledge of risk factors, it is worth noting that none of them presented a HTLV-I/HIV-1 double infection, which is very frequent in intravenous drug abusers, the major risk group in Italy. On the basis of these data spread of HTLV-I and HIV-1 appears to be more important in Italy than previously thought, and not confined to well-defined groups or, at least, among those who believe they do not belong to a risk group and therefore can represent a major vehicle for virus diffusion. Institution of screening for HTLV-I in blood donors should be taken immediately, and retrovirus infection risk criteria must be revised
Andamento dell'ansia, della paura e del dolore in un gruppo di pazienti ricoverati per intervento di colecistectomia semplice
No full textSono state analizzate con l'impiego di 4 test di autovalutazione alcune delle più importanti modificazioni psicologiche indotte dall'intervento chirurgico e dall'anestesia generale in 24 pazienti ricoverati per essere sottoposti a colecistectomia semplice. Le valutazioni effettuate prima e dopo l'intervento hanno mostrato come i pazienti più correttamente informati dal chirurgo prima dell'intervento anche con l'ausilio di una più appropriata terapia farmacologica, avevano una migliore reazione emotiva e di dolenzia post-operatorie
Effects of prazosin on the cAMP system in the sphontaneously hypertensive rat aorta
No full text3',5'-adenosine monophosphate (cAMP), adenylate cyclase and cAMP-phosphodiesterase (PDE) activity were measured in aorta homogenates from normal and spontaneously hypertensive rats (SHR) during treatment with prazosin, an antihypertensive drug. cAMP levels were lower in SHR than in normal rats. In SHR prazosin treatment induced marked inhibition of PDE activity thus causing an increase in cAMP levels; adenylate cyclase activity remained unaffected. This effect was only present for the first 32 days of drug administration
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