1,721,001 research outputs found
Comparing warfarin to aspirin (WoA) after aortic valve replacement with the St. Jude Medical Epic heart valve bioprosthesis: results of the WoA Epic pilot trial.
No full textPatients with bioprosthetic heart valves have a higher risk of developing peripheral arterial embolic phenomena than the normal population. Antithrombotic therapy during the early postoperative period after bioprosthetic aortic valve replacement (BAVR) is controversial. This prospective pilot study sought to investigate the feasibility of a larger trial and the efficacy of postoperative warfarin compared to acetyl salicylic acid (aspirin; ASA) in patients after AVR with the St. Jude Epic porcine bioprosthesis (SJEP), and the feasibility of conducting a larger trial.
METHODS:
Patients undergoing isolated BAVR were allocated at random to two groups, each of which received different antithrombotic therapies: (i) warfarin (INR; range 2-3) for the first three months, followed by ASA (100 mg/day); or (ii) ASA alone (100 mg/day).
RESULTS:
During 2003 and 2004, a total of 75 patients underwent isolated BAVR with the SJEP. Six patients who developed postoperative de-novo atrial fibrillation that did not revert to sinus rhythm were excluded from the analysis, but included in the follow up. One postoperative cerebral ischemic event occurred in each group between 24 h and three months (2.8% versus 2.9%, p = NS). The rates of major bleeding, stroke-free survival and overall survival were similar in both groups.
CONCLUSION:
The early results of this WoA Epic pilot trial did not support the suggestion that patients receiving the SJEP, and tissue valves in general, should be administered warfarin to prevent valve thrombosis and peripheral arterial embolic phenomena
Video-assisted cardioscopy for removal of primary left ventricular myxoma.
Full text linkLeft ventricular myxoma is a rare benign cardiac tumor. Surgical excision is the treatment of choice and completeness of removal is
mandatory to avoid late recurrence. A case is presented in which aortic transvalvular video-assisted cardioscopy was used to facilitate
removal
The ability of Salmonella to drill holes in the aorta.
Full text linkA 56-year-old male with fever and enlarged mediastinum
underwent examinations for lymphoma. He had back pain
and hypotension. Computed tomography showed a false
aneurysm of the aortic arch (Fig. 1a). Pathological aorta
was excised. Reconstruction of the large hole on the aortic
arch (Fig. 1b) with oval patch tailored from cryopreserved
thoracic aorta was performed under hypothermic circulatory
arrest. Blood and aortic cultures grew Salmonella. The
patient had uneventful recovery. One year later is free
from infection
Heart fatty acid biding protein in the diagnosis of myocardial infarction: where do we stand today?
No full textThe grandparent and the grandchild separated by 50 years sharing the left ventricular outflow tract
No full text
Comparing warfarin to aspirin (WoA) after aortic valve replacement with the St. Jude Medical Epic heart valve bioprosthesis: results of the WoA Epic pilot trial.
No full textDegeneration of native and tissue prosthetic valve in aortic position: Do statins play an effective role in prevention?
No full text- …
