1,721,075 research outputs found

    Effects of adding Naloxone on in vitro survival of bovine embryos

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    IACONO E, MERLO B, DELL'AQUILA M.E., MARI G (2007). Effects of adding Naloxone on in vitro survival of bovine embryos. REPRODUCTION IN DOMESTIC ANIMALS, ISSN: 0936-6768 Proc. 11th Annual Meeting of the European Society of Domestic Animal Reproduction (ESDAR) Mariensee- Hannover - Celle Germany 20-22 September 2007. Poster N° 8

    Stem Cells in Domestic Animals: Applications in Health and Production

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    In the last decade, researchers described Mesenchymal Stem/stromal cells (MSCs) as a possible population of cells for cell-based therapies in regenerative medicine, both for humans and animals. The aim of this first article (and the aim of the next books in this collection) is to gather high-quality research and review articles that could broaden knowledge regarding the role of MSCs in domestic animals’ health and production

    Beyond Canine Adipose Tissue-Derived Mesenchymal Stem/Stromal Cells Transplantation: An Update on Their Secretome Characterization and Applications

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    : A dog is a valuable animal model and concomitantly a pet for which advanced therapies are increasingly in demand. The characteristics of mesenchymal stem/stromal cells (MSCs) have made cell therapy more clinically attractive. During the last decade, research on the MSC therapeutic effectiveness has demonstrated that tissue regeneration is primarily mediated by paracrine factors, which are included under the name of secretome. Secretome is a mixture of soluble factors and a variety of extracellular vesicles. The use of secretome for therapeutic purposes could have some advantages compared to cell-based therapies, such as lower immunogenicity and easy manufacturing, manipulation, and storage. The conditioned medium and extracellular vesicles derived from MSCs have the potential to be employed as new treatments in veterinary medicine. This review provides an update on the state-of-the-art characterization and applications of canine adipose tissue-derived MSC secretome

    Micro-nanoplastics pollution and mammalian fertility: A systematic review and meta-analysis

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    Micro: and nanoplastics (MNPs) are fragments derived from physical, chemical, or biological degradation of plastic items. MNPs are one of the main sources of both marine and terrestrial plastic pollution. This study systematically and meta-analytically assesses the reproductive toxicity in mammals of key plastic components found in MNPs, focusing on polystyrene (PS), polyethylene (PE), polypropylene (PP), polyethylene terephthalate (PET), and polyvinyl chloride (PVC). PubMed, Medline, and CAB Abstracts databases were used to identify the relevant scientific papers, and 79 articles were selected for the systematic review. Six articles included two different species, and 19 papers contained both in vivo and in vitro studies, resulting in a total of 102 experiments being considered and analysed in the meta-analysis. Interest in the reproductive toxicity of MNPs in mammals has increased, peaking in the last two years. Five species (rat, mouse, bovine, pig, and human) have been studied, with most experiments carried out in vivo in mice, focusing on male fertility. The most studied plastic polymer is PS, and both micro- and nanoparticles were tested at single or multiple concentrations. Toxic effects are documented across various species, particle size, and polymer type. A pronounced concentrationdependent toxicity has been observed, particularly at high concentrations/doses of MNPs. There is a gap in research on food-producing animals, which are both relevant models for human health and potential vectors for MNPs into the human food supply chain. Overall, these findings emphasizpe the importance of continued research to elucidate the pathways and mechanisms through which MNPs impact mammalian reproductive health, ultimately advancing our understanding of how these pervasive pollutants interact with biological systems across diverse species

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Author Index

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