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Uterine tumors resembling ovarian sex cord tumors: a case report of conservative management in young women.
No full textInt J Gynecol Cancer. 2009 May;19(4):808-10.
Uterine tumors resembling ovarian sex cord tumors: a case report of conservative management in young women.
Berretta R, Patrelli TS, Fadda GM, Merisio C, Gramellini D, Nardelli GB.
SourceDepartment of Obstetrics and Gynecology, University of Parma, Parma, Italy. [email protected]
Abstract
Uterine tumors resembling ovarian sex cord tumors (UTROSCT) are distinguished into two separate groups: endometrial stromal tumors with sex cord-like elements (Group I), which have an unfavorable prognosis; and UTROSCT proper (group II), with more than 40% sex cord-like differentiation and less endometrial component, which are biologically less aggressive than the tumors of the other group. We report the case of a young woman with UTROSCT treated by minimally invasive hysteroscopic surgery. This is one of the few cases reported in the literature that have been managed conservatively
Randomised prospective study of abdominal wall closure in patients with gynaecological cancer.
No full textAust N Z J Obstet Gynaecol. 2010 Aug;50(4):391-6.
Randomised prospective study of abdominal wall closure in patients with gynaecological cancer.
Berretta R, Rolla M, Patrelli TS, Piantelli G, Merisio C, Melpignano M, Nardelli GB, Modena AB.
SourceDepartment of Obstetrics and Gynecology, University of Parma, Italy. [email protected]
Abstract
BACKGROUND: Median laparotomy is the most common approach to the abdominopelvic cavity in patients with gynaecological tumours.
AIMS: The primary endpoint of the study was to evaluate the onset of incisional hernia. The secondary endpoint was to evaluate the onset of infection, wound dehiscence, wound infection, and scar pain during the post-operative period.
METHODS: A total of 191 patients were eligible for the study. They were divided into three groups. Group A underwent en bloc closure of the peritoneum and fascia with Premilene suture, Group B en bloc closure of the peritoneum and fascia with Polydioxanone suture, and Group C separate closure of the peritoneum and fascia with single stitches of Ethibond suture. Statistical analysis was performed using the Statistical Software Package for Social Sciences 12.0.
RESULTS: Group A and Group B comprised 63 patients, and Group C included 65 patients. The three groups proved homogeneous on statistical analysis (P > 0.05). The statistical analysis did not reveal significant differences between the different suture types and techniques with respect to the incidence of incisional hernia (P > 0.05).
CONCLUSION: In our study, the incidence of incisional hernia was 8%. Randomised patients were homogeneous for sample size and risk factors. No significant differences were found between suture types or techniques. Currently, there is no suture material or technique that can be considered superior to others. When possible, we believe that the best way to prevent incisional hernia is to preserve the integrity of the abdominal wall using minimally invasive techniques
Vaginal versus abdominal hysterectomy in endometrial cancer: a retrospective study in a selective population
No full textInt J Gynecol Cancer. 2008 Jul-Aug;18(4):797-802. Epub 2007 Oct 18.
Vaginal versus abdominal hysterectomy in endometrial cancer: a retrospective study in a selective population.
Berretta R, Merisio C, Melpignano M, Rolla M, Ceccaroni M, DE Ioris A, Patrelli TS, Nardelli GB.
SourceDepartment of Gynecology, Obstetrics and Neonatology, University of Parma, Parma, Italy. [email protected]
Abstract
The purpose of this study was to analyze the outcome of vaginal and abdominal hysterectomy for the treatment of early-stage endometrial cancer in a selected group of elder patients. This retrospective study analyzed a total of 154 patients: 113 (group I) underwent vaginal surgery and 41 (group II) underwent laparotomy. In both groups, we investigated the following parameters: intra- and postoperative complications, mean operative time, mean hospital stay, disease-free survival (DFS), overall survival (OS), and time of local or retroperitoneal recurrence. Medically compromised patients were significantly more frequent in the vaginal surgery group (P = 0.005), and the operative duration in this group was significantly shorter (P = 0.01). Intra- and postoperative complications, along with local and distant recurrence, did not show a statistically significant difference in the two groups. Total survival in the two populations, 85% at 5 years, did not reach statistically significant difference either in terms of DFS or in terms of OS. Vaginal surgery compared to traditional abdominal approach is feasible also in patients with high surgical risk; it does not require general anesthesia, abolishes abdominal trauma correlated to laparotomy, and allows a quicker reprise of the bladder and rectal function; therefore, it achieves high eradication rates and low intra- and postoperative morbidity rates
Uterine smooth muscle tumor of uncertain malignant potential: a three-case report.
Full text linkInt J Gynecol Cancer. 2008 Sep-Oct;18(5):1121-6. Epub 2007 Nov 6.
Uterine smooth muscle tumor of uncertain malignant potential: a three-case report.
Berretta R, Rolla M, Merisio C, Giordano G, Nardelli GB.
SourceDepartment of Obstetrics and Gynecology, University of Parma, Parma, Italy. [email protected]
Abstract
Based on the degree of cytologic atypia, mitotic activity, and other features, uterine smooth muscle tumors have historically been grouped into two classes: benign leiomyomas and malignant leiomyosarcomas. However, this separation holds true more in principle than in practice because the tumor's biological potential may not always be determined with certainty, complicating diagnosis, and therapy. We report three cases of patients with uterine smooth muscle tumors of uncertain malignant potential. Surgery was radical in two and conservative in one. During the follow-up, one patient developed diffuse lung metastases. The two other patients have not shown any signs of relapse to date. Uterine smooth muscle tumors of uncertain malignant potential may have an unpredictable clinical course and may metastasize to seemingly low-grade neoplasms in distant sites even after several years and even in the absence of important negative prognostic predictors, such as coagulative tumor cell necrosis. At present, no final consensus has been reached on the choice of the best strategy for surgery and adjuvant therapy
Two cases of low-grade endomeriod carcinoma associated with undifferentiated carcinoma of the uterus (dedifferentiated carcinoma): A molecular study
No full textTWO CASES OF LOW-GRADE ENDOMETRIOD CARCINOMA ASSOCIATED WITH UNDIFFERETIATED CARCINOMA OF THE UTERUS (DEDIFFERENTIATED CARCINOMA): A MOLECULAR STUDY
No full textAdapting to Cancer with Body, Mind, and Heart: Psychological,Psychophysiological Assessment and Management in Sample of Ovarian Cancer Survivors
Full text linkObjective: Ovarian cancer survivors often develop severe
psychological disorders and impairments in social, familial, and
sexual functioning. They experience a withdrawal from intimate
relationship, fear and body shame, and a condition of unrelenting
distress. Heart rate variability (HRV) is a physiological parameter
that, when reduced, is index of higher distress. The quantitative
observational study aimed at understanding the relationship
between psychological adjustment, distress, and quality of life.
Methods: 44 women, consecutively recruited at the Oncological
service of the Gynecological Dept., filled questionnaires investigating
social support, body image, coping strategies and quality of life and
recorded short-term HRV.
Results: significant correlations appeared between: quality of life
functioning scales and body image, perceived social support and
coping strategies; perceived support from the significant other
and HRV (r=339 p <05), role functioning and HRV (r=479 p<001).
Simple regressions on HRV showed the effect of the significant
other’s support (F=4.27 p<05) and of role functioning (F=9.810
p<001), while body image showed its effect on quality of life (F=4.18
p<05). Multiple regression on HRV showed the effect of body image
(β=453), support from friends (β=-435) and avoidance (β=-391)
while fatalism showed an effect on quality of life (β=364, p<05).
Conclusion: Higher concerns on body image seem linked to a
worsened day-to-day life. Reporting these concerns contributes
to raise HRV, while better emotive disclosure reduces emotional
distress. Social support positively influences quality of life and HRV.
Fatalism facilitates cancer acceptance process. Proper emotive
disclosure may have a positive impact on life quality
Ruolo dell'HPV nello sviluppo delle neoplasie ovariche epiteliali maligne e a malignita' borderline
No full text- …
