1,720,981 research outputs found
Dexamethasone action in Ataxia-Telangiectasia: seeking the molecular mechanism of phenotype reversion
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Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Influence of host plant and different nutritional supplies on morphology and gene expression in Tuber borchii
No full textDispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Morphological and molecular modifications induced by different carbohydrate sources in Tuber borchii Vittad. mycelium
No full textDuring the different phases of mycorrhizal fungi life cycle,
several morphological, genetic and metabolic modifications
are induced for both symbiotic partners. These changes are
influenced by multiple environmental factors: light, gravity,
oxygen, temperature, soil typology, nutrient availability, root
exudates (that may content sugars) and the presence of particular
bacterial populations in the mycorrhizosphere.
Herein, in order to verify if nutritional supply leads to cell signaling
events and morpho-functional changes in Tuber borchii
pure culture, the expression level of genes involved in the
apical growth, was investigated using the array technique, on
mycelia grown on culture media containing different carbon
sources. Membranes were prepared using ESTs involved in
polarized growth, such as: S97, codifying the protein sec1, responsible
for binding Syntaxin and involved in vesicle membrane
fusion; S102, involved in apical growth, that codify a
1,3-beta-glucanosil transferase responsible for cell wall assembly
of fungi; S32, directly involved in cell nuclear migration
towards hyphae apical tips by cytoskeleton.
The results obtained by morphological analyses highlighted
an increased growth of T. borchii mycelium in the presence of
glucose, while the hyphae are thinner and less branched in the
presence of sucrose and maltose. These data were confirmed
by gene expression analyses: the genes involved in apical
grown and general metabolism are more expressed.
Since glucose is also present in root plant exudates, it can act
as a signal for the fungus to indicate the presence of the plant,
and to induce the complex symbiotic process. These mechanisms
can lead to morphological modifications, among which
an increase branching, necessary for the fungus to get closer
to the plant roots and establish a contact.
This study represents a starting point to identify
and characterise genes and proteins involved in
the complex morphological, genetic and metabolic
modifications that happens during Tuber life cycle
Binding force measurement of NF-kB-ODNs Interaction: an AFM based decoy and drug testing tool
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