1,720,979 research outputs found
Pharmacist-led patient education improves medication self-management and adherence in chronic hepatitis D virus patients: insights from the EXPLAIN project
No full textTaking care of caregivers: enhancing proper medication management for palliative care children with polypharmacy
Full text linkNo abstract availabl
Efficacy and safety of antiviral treatments for symptomatic COVID-19 outpatients: network meta-analysis and budget impact analysis
Full text linkHeterogeneity of the Italian residency training in hospital pharmacy: a pilot study from students’ perspective
Full text linkHeterogeneity of the Italian residency training in hospital pharmacy: a pilot study from students’ perspectiv
Preparation of intravenous chemotherapy bags: evaluation of a dose banding approach in an Italian oncology hospital
Full text linkIntroduction: Dose banding is an original approach that manages intravenous (IV) chemotherapy preparation by
generating on a weekly basis a series of bags containing scaled dosages of the active agent. These predetermined,
fixed dosage bags are intended to replace the traditional bags prepared daily that contain fully individualized dosages.
Methods: Three different scenarios were examined: (1) the current method of daily preparation of individualized
bags at the hospital pharmacy; (2) the weekly preparation at the hospital pharmacy of non-individualized bags
containing discrete, predefined doses covering an adequate range of doses (dose banding); (3) the use of commercial
ready-to-use bags based on the same approach of dose banding. The objective of this study was to compare
these three different approaches in terms of cost per patient. We considered five cancer drugs (gemcitabine,
oxaliplatin, paclitaxel, trastuzumab and 5-fluorouracil) that were suitable for the dose ranging approach. Appropriate
dose bands for these five agents were identified. Costs were estimated for each of the three approaches.
Results: A total of 13,490 fully individualized bags were studied, which corresponded to the real bags prepared
at our institution for these five agents in 2018. Dose banding was predicted to determine savings ranging from
€10,998 (−0.84%) for trastuzumab to €169,429.60 (−8.39%) for paclitaxel.
Conclusion: The introduction of dose banding can determine economic savings along with other advantages,
such as improved work conditions, management reorganization and containment of waste. The pharmaceutical
industry can hopefully support these experiences by producing ready-to-use bags in predetermined dosages
Long-Term Macrolides in Chronic Respiratory Diseases: Dusk or a New Dawn? A Narrative Review
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Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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