19 research outputs found

    Is intrapartum fever associated with ST-waveform changes of the fetal electrocardiogram? A retrospective cohort study

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    ObjectiveTo investigate the association between maternal intrapartum fever and ST-waveform changes of the fetal electrocardiogram.DesignRetrospective cohort study.SettingThree academic and six non-academic teaching hospitals in the Netherlands.PopulationLabouring women with a high-risk singleton pregnancy in cephalic position beyond 36 weeks of gestation.MethodsWe studied 142 women with fever (≥38.0°C) during labour and 141 women with normal temperature who had been included in two previous studies. In both groups, we counted the number and type of ST-events and classified them as significant (intervention needed) or not significant, based on STAN(®) clinical guidelines.Main outcome measuresNumber and type of ST-events.ResultsBoth univariable and multivariable regression analysis showed no association between the presence of maternal intrapartum fever and the number or type of ST-events.ConclusionsMaternal intrapartum fever is not associated with ST-segment changes of the fetal electrocardiogram. Interpretation of ST-changes in labouring women with fever should therefore not differ from other situations.JH Becker, J van Rijswijk, B Versteijnen, ACC Evers, ESA van den Akker, E van Beek, AC Bolte, RJP Rijnders, BWJ Mol, KGM Moons, MM Porath, AP Drogtrop, NWE Schuitemaker, C Willekes, MEMH Westerhuis, GHA Visser, A Kwee

    Developers’ vertical price premium behavior in residential tall buildings: A study on vertical price premiums and their determinants for apartments in Rotterdam’s residential tall buildings

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    Even though both the number and the size of tall building developments are increasing, tall building economics remain understudied. The goal of the research is to study developer behavior regarding height premiums in residential tall buildings. Literature offers little knowledge on developers’ behavior when it comes to height premiums in the residential sector. Previous findings on the demand side of height premiums indicate that willingness to pay for height benefits depends user preferences, but all signal that higher floors offer characteristics that can be priced by developers. Contextually relevant height benefits in the residential sector are categorized as views and perception of social power. This research employs data from fifteen residential tall buildings in Rotterdam and analyzes the relation between developer unit prices, floor levels and height benefits. Results display a 0.5% increase in developer unit prices per floor level, ceteris paribus. However, a deeper analysis shows that height premiums display inter-building and intra-building differences, which is interpreted as evidence for heterogenous vertical price premium behavior amongst developers. The floor level premiums were found to be substantially impacted by height-induced view effects. The results further show that developers place a price on status aspects related to height. Penthouses premiums were found to be larger when placed on a greater vertical location and some developers seem to put a price label on the concept of being located on top of others. These novel insights can help various stakeholders to better understand developer vertical price premium behavior

    TURMAC Toegankelijk: Interventie in een voormalig sigarettenfabriek te Zevenaar

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    Interventie in een voormalige sigarettenfabriek te Zevenaar, hoe maak ke deze publiek toegankelijk zodat het karakter van het fabrieksterrein behouden blijft maar er ook een stap naar een nieuwe publieke functie wordt gemaakt. Dit heeft geleid tot een ontwerp voor een multifunctioneel centrum in de fabriekshal met onderandere een brede school.RMITArchitectur

    Strengthen the adaptability of the ERTMS implementation

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    The number of operational rail corridors equipped with ERTMS is increasing throughout Europe. The implementation of this critical safety system is planned to take several decades. However, ERTMS is a complex system that evolves continuously increasing the risk of using outdated parts and components. Therefore, adaptability is required for an efficient process. Adaptability is the ability of a system to meet technological or functional changes without requiring structural modifications or replacements. This paper identifies factors that influence adaptability and researches critical issues for future adaptability of ERTMS. With these factors and issues, solutions are proposed that are validated in a use case and integrated in a strategy that strengthens adaptability of ERTMS for future operational needs. The main takeaways of this strategy is the need for technical modularity and a balanced stakeholder involvement in the implementation process.Transport, Infrastructure and Logistic

    De oorspronkelijke gedaante van de geschilderde kamer in het Martenahuis te Franeker

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    The Martenahuis in Franeker contains a special room whose walls and ceiling are decorated with vast paintings on canvas. Such fully painted rooms were very popular in the northern Dutch provinces from the last quarter of the seventeenth century and were called ‘painted rooms’ or ‘rooms in the round’. Owing to later additions and alterations, the painted room in the Martenahuis presents a disjointed picture today. The room’s original appearance has been reconstructed with the help of material-technical, art-historical and archival research. It transpires that all the elements of the room were meticulously coordinated with one another, which provides insight into the intentions of the client and the artists involved.The now white-painted flat wooden architectural elements were originally painted with a reddish-brown trompe l’oeil representation which, together with the paintings inserted into them, created the illusion of a richly decorated classical pavilion overlooking Arcadian landscapes. Technical research revealed – in contrast to what the literature had previously suggested – that all the landscape hangings, as well as the central ceiling piece and the eight original wainscot paintings, were part of a single series made especially for this room. Archival research has shown that the room came into being in or shortly after 1701, following the departure in August 1701 of the young Frisian stadholder Johan Willem Friso (1687-1711), who had stayed there while studying at Franeker University. The construction of the room was part of a large-scale renovation commissioned by the wealthy regent Suffridus Westerhuis (1668-1731), who had acquired the building in 1694. Various prints by the French architect Daniel Marot (1661-1752) served as inspiration for the room’s design. Those designs were all published before 1703. There are no elements dating back to Marot’s inventions from or after 1703, such as those included in his collected edition of 1712, whereas this is regularly the case in Frisian buildings built after 1703. As such, the painted room in the Martenahuis is one of the earliest examples of the Marot style in an upper middle-class mansion. The ambitious Suffridus Westerhuis presented himself as a modern and wealthy man of standing by having his house renovated in line with the latest architectural and interior design ideas. What’s more, the painted room he created directly mirrored Marot’s designs for Willem III (1650-1702) and his inner circle. One of the artists Westerhuis chose to do the landscape paintings in his reception room was the painter Jan van Bunnik (1654-1733), who created decorations for the palaces of the stadholder-king and for the country houses of his entourage. In seeking to align himself with the Republic’s highest echelons, Westerhuis was presenting himself as an administrator of high standing. Westerhuis took a keen interest in gardening and the study of nature, a highly appropriate pastime for a prominent figure at that time. As such, his choice of landscape hangings as wall decoration was quite apt. The contemplation of such landscapes was viewed at the time as a form of relaxation after onerous administrative duties. Architecture, paintings and client turn out to be inextricably linked in the Martenahuis room – a connection which, after having been concealed for centuries, has been brought to light by this recent research project

    Discriminant Q2 (DQ2) for improved discrimination in PLSDA models

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    In this paper we introduce discriminant Q2 (DQ2) as an improvement for the Q2 value used in the validation of PLSDA models. DQ2 does not penalize class predictions beyond the class label value. With rigorous Monte Carlo simulations we show that when DQ2 is used, a smaller effect can be found statistically significant than when the standard Q2 is used. © The Author(s) 2008

    Big fish from little ponds: Solvay, Belgium, global markets, and family firms

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    We are accustomed to the idea that single families control a number of our largest firms. In Australia the Murdochs in media, the Lowys in retail and Gina Rinehart and her estranged children in the resources sector occupy us in the business, social, and occasionally the sports sections of our daily news. Beyond the enjoyment of reading and watching the activities of the extremely rich, family firms also raise serious questions, about entrepreneurship, about firm governance, about varieties of capitalist systems and about the functioning of markets. Four books give a fascinating insight as Ben Tipton\u27s lively review essay in the Australian Review of Public Affairs reveals.   Book Title: Solvay: History of a Multinational Family Firm Publisher: Cambridge University Press Date published: 2014 Authors: Kenneth Bertrams, Nicolas Coupain and Ernst Homburg Book Title: Family Multinationals: Entrepreneurship, Governance, and Pathways to Internationalization Publisher: Routledge Date published: 2013 Authors: Christina Lubinski, Jeffrey Fear and Paloma Fernández Pérez (eds) Book Title: The Power of Corporate Networks: A Comparative and Historical Perspective Publisher: Routledge Date published: 2014 Authors: Thomas David and Gerarda Westerhuis (eds) Book Title: Varieties of Capitalism and Business History: The Dutch Case Publisher: Routledge Date published: 2015 Author: Keetie E. Sluyterman (ed.

    Heart rate variability in hypertensive pregnancy disorders:a systematic review

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    \u3cp\u3eBACKGROUND: Hypertensive pregnancy disorders (HPD) are associated with dysfunction of the autonomic nervous system. Cardiac autonomic functions can be assessed by heart rate variability (HRV) measurements.\u3c/p\u3e\u3cp\u3eOBJECTIVE: To study whether HRV detects differences in the function of the autonomic nervous system between pregnant women with HPD compared to normotensive pregnant women and between women with a history of a pregnancy complicated by HPD compared to women with a history of an uncomplicated pregnancy.\u3c/p\u3e\u3cp\u3eMETHODS: A systematic search was performed in Medline, EMBASE, and CENTRAL to identify studies comparing HRV between pregnant women with HPD or women with a history of HPD to women with (a history of) normotensive pregnancies.\u3c/p\u3e\u3cp\u3eRESULTS: The search identified 523 articles of which 24 were included in this review, including 850 women with (a history of) HPD and 1205 normotensive controls. The included studies showed a large heterogenicity. A decrease in overall HRV was found in preeclampsia (PE), compared to normotensive pregnant controls. A trend is seen towards increased low frequency/high frequency-ratio in women with PE compared to normotensive pregnant controls.\u3c/p\u3e\u3cp\u3eCONCLUSION: Our systematic review supports the hypothesis a sympathetic overdrive is found in HPD which is associated with a parasympathetic withdrawal. However, the included studies in our review showed a large diversity in the methods applied and their results.\u3c/p\u3
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