1,721,028 research outputs found

    Diagnostic imaging and therapy in a case of myasthenia gravis associated with thymic hyperplasia

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    The diagnostic approach to a patient with myasthenia gravis to verify the presence of thymic hyperplasia/thymoma is presented. The study of the mediastinal region was necessary. Mediastinal MRI showed the presence of a mass. The differential diagnosis between a mediastinal and an extramediastinal lesion is possible with MRI for its high contrast resolution, good spatial resolution and multiplanarity that allow the detection, localization, evaluation of the extent and/or infiltration of adjacent tissues/organs based on the analysis of adipose cleavages and typing in the different pulse sequences of pathologic tissue with contrast enhancement. Definitive diagnosis of thymic hyperplasia was established. Therefore surgery should be essentially associated with the severity of the clinical presentation rather than with thymic hyperplasia

    Surgical treatment of dacryocystitis by using a venous catheter

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    Purpose: Aim of this work is to highlight the advantages of a new surgical technique performed over 15 patients affected dacryocystitis and treated by using a venous catheter. The arrangement of a 30 mm venous catheter used at the end of a dacryocystectomy (DCT) was performed in 15 patients with dacryocystitis. The venous catheter was removed at 30 days after the surgery. The use of the venous catheter allows washing the lacrimal drainage system, reducing the risk of postoperative infections and supports the recanalization of the lacrimal drainage system 30 days after surgery. The presented cases demonstrated how the technique is easy and it reduces the possibility of the post-operative infection. It could be performed under regional anesthesia. Furthermore, after the surgery the recanalization of the lacrimal drainage system with a significant reduction of the epiphora in 6 months after surgery has been observed

    Cardiac magnetic resonance in systemic sclerosis patients with cardiac symptoms.

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    OBJECTIVE: Systemic sclerosis (SSc) is characterized by widespread vascular lesions and skin and internal organs fibrosis, including the heart; all cardiac layers, endocardium, myocardium, and pericardium, may be involved. We report the relevance of cardiac MRI findings in scleroderma patients with cardiac symptoms. PATIENTS AND METHODS: 50 patients, all fulfilling the ACR SSc criteria (19 with limited and 31 with diffused skin involvement) were evaluated using a 1.5T MR scanner. Images were acquired before and after contrast medium administration; the exams were considered positive with one or more of these findings: enlarged volumes, reduced EF, regional kinetic anomalies, edema, DE or pericardial effusion. RESULTS: 40 patients (80%) had one or more cardiac abnormalities: 5 patients had myocardial edema; 2 an increased interventricular septum thickness; 22 dilated ventricles or reduced EF; 12 an abnormal regional ventricular motion (2 of these with akinetic segments); 17 a delayed enhancement with different patterns, all without coronary distribution; 22 a pericardial effusion CONCLUSIONS: Pathologic findings were documented in 80% of the cases confirming a high occurrence of abnormal MR data. Myocardial involvement in systemic sclerosis can be assumed by the presence of multiple pathologic MRI findings. CMR seems to be a valuable tool to identify and assess the presence of cardiac involvement

    Chemically-boosted corneal cross-linking for the treatment of keratoconus through a riboflavin 0.25% optimized solution with high superoxide anion release

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    The purpose of this study was to evaluate the effectiveness and safety of a novel buffered riboflavin solution approved for corneal cross-linking (CXL) in progressive keratoconus and sec-ondary corneal ectasia. Following the in vivo preclinical study performed on New Zealand rabbits comparing the novel 0.25% riboflavin solution (Safecross®) containing 1% hydroxypropyl methyl-cellulose (HPMC) with a 0.25% riboflavin solution containing 0.10% EDTA, accelerated epithelium-off CXL was performed on 10 patients (10 eyes treated, with the contralateral eye used as control) through UV-A at a power setting of 9 mW/cm2 with a total dose of 5.4 J/cm2. Re-epithelialization was evaluated in the postoperative 7 days by fluorescein dye test at biomicroscopy; endothelial cell count and morphology (ECD) were analyzed by specular microscopy at the 1st and 6th month of follow-up and demarcation line depth (DLD) measured by anterior segment optical coherence to-mography (AS-OCT) one month after the treatment. We observed complete re-epithelization in all eyes between 72 and 96 h after surgery (88 h on average). ECD and morphology remained un-changed in all eyes. DLD was detected at a mean depth of 362 ± 50 μm, 20% over solutions with equivalent dosage. SafeCross® riboflavin solution chemically-boosted corneal cross-linking seems to optimize CXL oxidative reaction by higher superoxide anion release, improving DLD by a factor of 20%, without adverse events for corneal endothelium

    DIAGNOSTIC IMAGING INFORMATION SYSTEMS: DREAM. REPORTING MANAGEMENT

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    From the clinical standpoint, the report represents the synthesis of the diagnostic process and it is the central activity of radiology. However, reporting cannot be separated from the entire organizational cycle inside the Diagnostic Imaging Department as well as within the structure as a whole. The effectiveness of the contribution an information system can give to the radiologist is related to the information and functional integration of the various applications operating in the hospital and over the territory. Based on these considerations, the main types of support the information tool can offer, are reported together with the primary objectives which were basic to the development of the reporting module within the DREAM system and the major solutions adopted to facilitate the attainment of these objectives
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