1,723,215 research outputs found
Pedro Laín Entralgo. Il medico e il malato
L’edizione italiana de Il medico e il malato di Perdo Laín Entralgo consente di analizzare con cura il pensiero del medico e filosofo spagnolo del Novecento, aprendo spaccati nuovi di riflessione e ponendo questioni urgenti che riguardano la complessa visione etica e bioetica dell’uomo nel contesto odiern
Comunicare tra medico e malato: aspettative e realtà
Il Convegno ha evidenziato il ruolo della comunicazione medico-malato ai fini di un corretto metodo di cura. In particolare è stato ribadito il significato della medicina di relazione e l'importanza del dialogo interdisciplinare e inter-professionale
Il supporto medico e sociale della Pet Therapy
Il supporto medico e sociale della Pet Therap
Il ruolo dei familiari nella relazione tra medico e paziente
Il ruolo dei familiari nella relazione tra medico e pazient
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
“Medico e Bambino” on Facebook
Anche Medico e Bambino ha deciso di creare una sua pagina
su Facebook (http://www.facebook.com/medicoebambino),
in una prospettiva ancora tutta da definire, ma che è già attraente
per la possibilità di rendere disponibili in pochi secondi
molti dei contenuti della rivista che sono già on-line
(www.medicoebambino.com), ma anche per annunciare eventi
e notizie utili che provengono dal mondo pediatrico nazionale
e internazionale e per stimolare dibattiti
Machine learning for RNA sequencing-based intrinsic subtyping of breast cancer
Stratification of breast cancer (BC) into molecular subtypes by multigene expression assays is of demonstrated clinical utility. In principle, global RNA-sequencing (RNA-seq) should enable reconstructing existing transcriptional classifications of BC samples. Yet, it is not clear whether adaptation to RNA-seq of classifiers originally developed using PCR or microarrays, or reconstruction through machine learning (ML) is preferable. Hence, we focused on robustness and portability of PAM50, a nearest-centroid classifier developed on microarray data to identify five BC “intrinsic subtypes”. We found that standard PAM50 is profoundly affected by the composition of the sample cohort used for reference construction, and we propose a strategy, named AWCA, to mitigate this issue, improving classification robustness, with over 90% of concordance, and prognostic ability; we also show that AWCA-based PAM50 can even be applied as single-sample method. Furthermore, we explored five supervised learners to build robust, single-sample intrinsic subtype callers via RNA-seq. From our ML-based survey, regularized multiclass logistic regression (mLR) displayed the best performance, further increased by ad-hoc gene selection on the global transcriptome. On external test sets, mLR classifications reached 90% concordance with PAM50-based calls, without need of reference sample; mLR proven robustness and prognostic ability make it an equally valuable single-sample method to strengthen BC subtyping
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