62,462 research outputs found

    Theses ex l. 2. Rem maioris. C. de Rescind. vendit

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    Quas, Deo iuvante, ex decreto Amplissimi Collegii Antecessorum inclytae Basiliensis Academiae, ad obtinendum Docturae cingulum in utroque Iure, publice disputando tuebitur Matthias Indenius Marcoduranus[,] A.D. 7. Id. Augusti, hora septima, loco consuetoEnthält 29 ThesenDiss. iur. Basel, 158

    Deo Optimo Maximo Praeside, Consensu & Decreto Gratiosissimi Collegii Medici, In Inclyta Argentoratensium Universitate, Disputationem Inauguralem Medicam, De Aimoptysei seu Sputo Sanguinis ... ad diem [...] August. H. L. Q. C. Publico eruditorum examini sistit Andreas Matthias Volswets/ Clausthalensis

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    DEO OPTIMO MAXIMO PRAESIDE, CONSENSU & DECRETO GRATIOSISSIMI COLLEGII MEDICI, IN INCLYTA ARGENTORATENSIUM UNIVERSITATE, DISPUTATIONEM INAUGURALEM MEDICAM, DE AIMOPTYSEI SEU SPUTO SANGUINIS ... AD DIEM [...] AUGUST. H. L. Q. C. PUBLICO ERUDITORUM EXAMINI SISTIT ANDREAS MATTHIAS VOLSWETS/ CLAUSTHALENSIS Deo Optimo Maximo Praeside, Consensu & Decreto Gratiosissimi Collegii Medici, In Inclyta Argentoratensium Universitate, Disputationem Inauguralem Medicam, De Aimoptysei seu Sputo Sanguinis ... ad diem [...] August. H. L. Q. C. Publico eruditorum examini sistit Andreas Matthias Volswets/ Clausthalensis ( - ) Titelseite ( - ) Widmung ( - ) Prooemium (3) Caput I. - Caput VIII. (4) Beitrag von Georgius Franke (24

    Transport model of the human Na+-coupled L-ascorbic acid (vitamin C) transporter SVCT1

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    Vitamin C (L-ascorbic acid) is an essential micronutrient that serves as an antioxidant and as a cofactor in many enzymatic reactions. Intestinal absorption and renal reabsorption of the vitamin is mediated by the epithelial apical L-ascorbic acid cotransporter SVCT1 (SLC23A1). We explored the molecular mechanisms of SVCT1-mediated L-ascorbic acid transport using radiotracer and voltage-clamp techniques in RNA-injected Xenopus oocytes. L-ascorbic acid transport was saturable (K(0.5) approximately 70 microM), temperature dependent (Q(10) approximately 5), and energized by the Na(+) electrochemical potential gradient. We obtained a Na(+)-L-ascorbic acid coupling ratio of 2:1 from simultaneous measurement of currents and fluxes. L-ascorbic acid and Na(+) saturation kinetics as a function of cosubstrate concentrations revealed a simultaneous transport mechanism in which binding is ordered Na(+), L-ascorbic acid, Na(+). In the absence of L-ascorbic acid, SVCT1 mediated pre-steady-state currents that decayed with time constants 3-15 ms. Transients were described by single Boltzmann distributions. At 100 mM Na(+), maximal charge translocation (Q(max)) was approximately 25 nC, around a midpoint (V(0.5)) at -9 mV, and with apparent valence approximately -1. Q(max) was conserved upon progressive removal of Na(+), whereas V(0.5) shifted to more hyperpolarized potentials. Model simulation predicted that the pre-steady-state current predominantly results from an ion-well effect on binding of the first Na(+) partway within the membrane electric field. We present a transport model for SVCT1 that will provide a framework for investigating the impact of specific mutations and polymorphisms in SLC23A1 and help us better understand the contribution of SVCT1 to vitamin C metabolism in health and disease

    Bullingers Briefwechsel mit dem Elsässer Reformator Matthias Erb (1539-1571)

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    Betr. den in der Universitätsbibliothek Basel erhaltenen Briefnachlass von Matthias Er

    Erratum to: Effect of moderate red wine intake on cardiac prognosis after recent acute myocardial infarction of subjects with Type 2 diabetes mellitus (Diabetic Medicine, (2006), 23, 9, (974-981), 10.1111/j.1464-5491.2006.01886.x)

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    In an article by Marfella et al, the author name C. Saron is incorrect and should be listed as C. Sardu. Therefore the correct author list is: R. Marfella, F. Cacciapuoti, M. Siniscalchi, F. C. Sasso, F. Marchese, F. Cinone, E. Musacchio, M. A. Marfella, L. Ruggiero, G. Chiorazzo, D. Liberti, G. Chiorazzo, G. F. Nicoletti, C. Sardu, F. D'Andrea, C. Ammendola, M. Verza and L. Coppola.In an article by Marfella et al, the author name C. Saron is incorrect and should be listed as C. Sardu. Therefore the correct author list is: R. Marfella, F. Cacciapuoti, M. Siniscalchi, F. C. Sasso, F. Marchese, F. Cinone, E. Musacchio, M. A. Marfella, L. Ruggiero, G. Chiorazzo, D. Liberti, G. Chiorazzo, G. F. Nicoletti, C. Sardu, F. D'Andrea, C. Ammendola, M. Verza and L. Coppola

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    De Maiestate / Praeside M. Jacobo Thomasio, Moralis Philosoph. P. P., publice disputabit Johannes Dunte, R. L. Author & Respon: ad diem 9. Septembr. H L. Q. C.

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    DE MAIESTATE / PRAESIDE M. JACOBO THOMASIO, MORALIS PHILOSOPH. P. P., PUBLICE DISPUTABIT JOHANNES DUNTE, R. L. AUTHOR & RESPON: AD DIEM 9. SEPTEMBR. H L. Q. C. De Maiestate / Praeside M. Jacobo Thomasio, Moralis Philosoph. P. P., publice disputabit Johannes Dunte, R. L. Author & Respon: ad diem 9. Septembr. H L. Q. C. (1) Titelblatt (1) Widmung (2) Text (3) Beiträge (21
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