347 research outputs found

    Prandtl number effects on the decaying and the forced turbulence in stratified fluids

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    Effects of high-Prandtl number density-stratifying scalar, i.e., active scalar, on decaying and forced turbulence in stratified fluids are investigated by numerical simulations. In decaying turbulence, potential energy spectrum of the high-Prandtl number active scalar (Pr=6) agrees with the kinetic energy spectrum even at small scales. In forced steady turbulence, these two spectra again approach each other at small scales. These phenomena, which are in disagreement with the Batchelor scaling for a high-Schmidt number passive scalar, occur at scales even smaller than the Ozmidov scale, suggesting that these effects would not be negligible in general

    The Femme Fatale and the Exotic Queer within Shinya Tuskamoto\u27s Tetsuo: Gender as Narrative Tool within an Allegory for Post WWII Japan\u27s Industrialized Identity Crisis

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    Within Shinya Tsukamoto’s seminal independent horror masterpiece Tetsuo, the viewer’s perceptions of reality and the present are distorted within a temporally disjointed blend of horrific fantasy and banal existence; this instability reflects the vocal and subconscious critiques of historical ontological truths exhibited within the emergent transnational genres of Japanese cyberpunk and American Avant-pop ideologies of the late 1980’s. Author Takayuki Tatsumi uses Shinya Tsukamoto\u27s Tetsuo to illustrate the emergence of the Japanoid, a technologically driven fusion of American and Japanese post-war identity best understood as a manifestation of Donna Haraway\u27s socio-political cyborg. Tatsumi strongly advises avoiding interpretation through a queer lens, proposing that the use of “cyborg” and scrap iron serve as an analogy for the stratification and integration of disenfranchised post WWII Okinawan “scrap apaches.” However, Tetsuo’s prominent homoerotic elements cannot be ignored. Arguably, The film presents as blatantly non-heteronormative; to ignore queerness and instead focus solely on Tatsumi\u27s definition of identity ignores the meaning of masculinity in a patriarchal culture, rendering an incomplete (post)colonial reading. A queer reading clarifies Tsukamoto\u27s take on the contemporary disenfranchisement of the so-called Japanoid identity that Tatsumi embraces. Within Tetsuo, representation of woman as femme fatale and an overt queering of masculinity problematize the traditional heteronormative Japanese identity

    Was the 2012 Nobel Prize in medicine awarded for a Kuhnian paradigm shift? An author co-citation analysis perspective

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    Stem cell research has been a fast growing, highly successful, and at the same time highly controversial field in recent years. Using a highly optimized author co-citation analysis methodology to study the intellectual structure of this field over the time period 2004–2009, we find that the induced pluripotent stem cell breakthrough that earned Shinya Yamanaka the 2012 Nobel Prize in Medicine did indeed quickly redefine its entire research field, and thus might truly qualify as a “paradigm shift” in Kuhn’s sense

    Living cells and dynamic molecules observed with the polarized light microscope : the legacy of Shinya Inoué

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    Author Posting. © Marine Biological Laboratory, 2016. This article is posted here by permission of Marine Biological Laboratory for personal use, not for redistribution. The definitive version was published in Biological Bulletin 231 (2016): 85-95.In 1948, Shinya Inoué arrived in the United States for graduate studies at Princeton. A year later he came to Woods Hole, starting a long tradition of summer research at the Marine Biological Laboratory (MBL), which quickly became Inoué's scientific home. Primed by his Japanese mentor, Katsuma Dan, Inoué followed Dan's mantra to work with healthy, living cells, on a fundamental problem (mitosis), with a unique tool set that he refined for precise and quantitative observations (polarized light microscopy), and a fresh and brilliant mind that was unafraid of challenging current dogma. Building on this potent combination, Inoué contributed landmark observations and concepts in cell biology, including the notion that there are dynamic, fine structures inside living cells, in which molecular assemblies such as mitotic spindle fibers exist in delicate equilibrium with their molecular building blocks suspended in the cytoplasm. In the late 1970s and 1980s, Inoué and others at the MBL were instrumental in conceiving video microscopy, a groundbreaking technique which married light microscopy and electronic imaging, ushering in a revolution in how we know and what we know about living cells and the molecular mechanisms of life. Here, we recount some of Inoué's accomplishments and describe how his legacy has shaped current activities in polarized light imaging at the MBL.Preparation of this manuscript was supported by grants from the National Institutes of Health (no. GM100160 to TT; no. GM101701 to MS; and no. GM114274 to RO); and by the Marine Biological Laboratory start-up funds from the Inoue´ Family Endowment, to TT

    Trends in antimicrobial consumption : long-term impact of the COVID-19 pandemic

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    Abstract: Objectives: The COVID-19 pandemic was associated with a global decrease in antimicrobial consumption (AMC) in 2020. However, the persistence of this downwards trend is not known at a global level. This study examined the global and longer-term trends in AMC after the emergence of COVID-19. Methods: The change rate of AMC was compared (a) 2020 over 2019, (b) 2021 over 2020, and (c) 2022 over 2021 using monthly sales volume data of antimicrobials in 69 countries obtained from the IQVIA MIDAS information service. Changepoints were detected using time-series data of global monthly antimicrobial sales from November 2016 to December 2023. We defined antimicrobials as oral and parenteral drugs classified as J1 by the Anatomical Therapeutic Chemical code. Antimicrobial sales were reported in standard units, as defined by IQVIA. We assessed the data using standard units per 1000 population per day, with populations based on World Population Prospects data issued by the United Nations. In addition, interrupted time-series analysis was used to examine the impact of movement restrictions in G7 countries. Results: In the IQVIA MIDAS data, 68 of the 69 countries had more than one changepoint between 2016 and 2023. Of these 68 countries, 61 experienced a decrease in AMC after the COVID-19 pandemic started. However, 53 of these 61 countries showed a reverse increasing trend in AMC in 2022. Interrupted timeseries analysis revealed that movement restrictions had a negative impact on AMC in all G7 countries. Discussion: The global decrease in AMC in 2020 might not have been because of COVID-19 itself but to non-pharmaceutical interventions such as movement restrictions. Human mobility could possibly be one of the key determinants of antimicrobial use at the population level. Shinya Tsuzuki, Clin Microbiol Infect 2025;31:594 (c) 2024 The Author(s). Published by Elsevier Ltd on behalf of European Society of Clinical Microbiology and Infectious Diseases. This is an open access article under the CC BY-NC-ND license (http:// creativecommons.org/licenses/by-nc-nd/4.0/)

    (Re) Building proun #5A in the metaverse

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    During the years of Suprematism, between 1919 and 1923 in Russia, one of the movement's most significant contributors, architect, artist and designer El Lissitzky developed a series of works which he entitled "Prouns," a name the exact meaning of which El Lissitzky never fully revealed, although he later described the purpose of his creations as interchange stations from painting to architecture, i.e., from two dimensional to three dimensional visuality. The author has re-created El Lissitzky's "Proun #5A" from 1919 in the metaverse, as an architecture for avatars. The process in which the translation from analogue drawing to three dimensional digital artifact was undertaken, the challenges encountered during its re-building; framed within a literature review that examines both El Lissitzky's influence on contemporary cyber-architecture, as well as the significance of his spatial investigations and his sources of inspiration during the early decades of the twentieth century will form the contents of this text

    Numerical enclosure for each eigenvalue in generalized eigenvalue problem

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    AbstractAn algorithm for enclosing all eigenvalues in generalized eigenvalue problem Ax=λBx is proposed. This algorithm is applicable even if A∈Cn×n is not Hermitian and/or B∈Cn×n is not Hermitian positive definite, and supplies n error bounds while the algorithm previously developed by the author supplies a single error bound. It is proved that the error bounds obtained by the proposed algorithm are equal or smaller than that by the previous algorithm. Computational cost for the proposed algorithm is similar to that for the previous algorithm. Numerical results show the property of the proposed algorithm
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