1,721,209 research outputs found

    Solid-supported chloro-(1,3,5)-triazine. A versatile new synthetic auxiliary for the synthesis of amide libraries

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    [GRAPHICS] 2,4,6-Trichloro[1,3,5]triazine was loaded on different types of NH2-functional resins to give a new supported reagent. The best results, in term of yields products, were obtained using the chlorotriazine linked to a polystyrene-poly(ethylene glycol) resin. This reagent was employed for the solution-phase synthesis of different amides and dipeptides

    Lo sfruttamento dei molluschi marini in Sardegna

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    Esame dei ritrovamenti di conchiglie di molluschi in siti archeologici della Sardegna e valutazione del loro significato

    Solid phase synthesis of aziridine 2-carboxylates

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    Several oligopeptides and amino acids containing an aziridine 2-carboxylate group were prepared using a solid phase version of the Gabriel-Cromwell reaction. Wang resin loaded with different Fmoc amino acids was employed as the substrates and two different strategies were explored. Aziridine oligopeptides were prepared by addition of resin containing NH2 groups to alpha-bromoacrylates and alpha-acrylamides or by addition of different primary amines to bromoacrylates loaded on the resin. (C) 1999 Elsevier Science Ltd. All rights reserved
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