1,721,008 research outputs found

    Gli aminoacidi nel trattamento delle ferite croniche dei piccoli animali

    No full text
    Il lavoro valuta gli effetti del VL su ferite traumatiche croniche del cane e del gatto. Il VL è un dressing a base di sodio ialuronato e dei quattro aminoacidi essenziali per la produzione di collagene (glicina, L-lisina, L-prolina e L-leucina) in determinati rapporti stechiometrici che stimola la chiusura delle ferite e induce la rigenerazione tissutale. Rispetto all’uso di un prodotto a base di acido ialuronico, l’uso del VL determina una più rapida riattivazione del processo di cicatrizzazioneThe effects of a new commercially available wound dressing called VL are investigated on chronic wounds in dogs and cats. It contain four essential aminoacids for collagen and elastin synthesis (glycine, L-lysine, L-proline and L-leucine) in an expressly calculated steichiometric ratio together with sodium ialuronate (Na-Ial) that induces wound closure and tissue regeneration. When compared with results from control group treated with ialuronic acid the use of VL seems to accelerate wound healing

    Due casi di infestazione da Rhinoestrus spp. nel cavallo

    No full text
    Gli Autori riferiscono sull’infestazione da larve di Rhinoestrus spp. in due cavalli sportivi affetti da ematoma progressivo dell’etmoide ed emiplegia laringea (I grado). Normalmente il riscontro della parassitosi avviene in sede autoptica mentre in questo caso è stata diagnosticata in vivo per mezzo di esame endoscopico. Il trattamento chemioterapico ha consentito la completa risoluzione della miasi. La parassitosi va annoverata tra le possibili diagnosi differenziali in caso di rumori respiratori, intolleranza all’esercizio e sintomatologia respiratoria del cavallo

    Lumbar interbody expanding cage: a preliminary study on an animal model

    No full text
    Interbody fusion devices are used in human medicine for treating degenerative diseases of the spine. Currently, there is not a universally accepted assessment tool for determining fusion, and the definitive criteria for diagnosing a successful interbody fusion remain controversial. The aim of this study was to describe microscopic and helical computed tomography (CT) imaging in the assessment of lumbar interbody fusion using cylindrical threaded titanium expanding cage in sheep. One cylindrical threaded expanding titanium cage (Proconcept – SA, Orange, France) was inserted through a transperitoneal approach after radical discectomy and packed with cancellous bone autograft in five adult sheep. The subjects were euthanatized after three, six, 12, 18 and 24 months. CT images revealed lumbar fusion at 12 months post operation, whereas microscopic evaluations indicated the presence of lumbar fusion at 18 months. CT and histological grades were the same in 65% of the cases observed. There were not a significant difference between CT, histological and micro radiographic grades. Helical CT scanning can be considered to be a suitable method for the monitoring of lumbar fusion as it enables observation of the deposition of bony bridging within the cage

    Repeated platelet concentrate injections enhance reparative response of microfractures in the treatment of chondral defects of the knee: an experimental study in an animal model

    No full text
    PURPOSE: To assess the histology and biomechanics of repair cartilage after microfractures with and without repeated local injections of platelet concentrate for the treatment of full-thickness focal chondral defects of the knee. METHODS: A full-thickness chondral lesion on the medial femoral condyle was created in 30 sheep and treated with microfractures. Animals were divided into 2 groups, according to postoperative treatment: in group 1 we performed 5 weekly injections of autologous conditioned plasma, whereas group 2 did not undergo further treatments. Animals were killed at 3, 6, and 12 months after treatment. Macroscopic, histologic, and biomechanical evaluations were performed. Differences between groups at each time interval and differences over time within groups were analyzed for each outcome. Significance was set at P < .05. RESULTS: Group 1 showed significantly better macroscopic, histologic, and biomechanical results than group 2 at each time interval. Analysis of time effect within groups showed that in group 1, quality of repair tissue significantly improved from 3 to 6 months after treatment and remained stable over time for all the outcomes; in group 2 a significant histologic and mechanical deterioration was observed between 6 and 12 months' follow-up. CONCLUSIONS: Five repeated local injections of autologous conditioned plasma after microfractures in the treatment of full-thickness cartilage injuries promoted a better and more durable reparative response than isolated microfractures, although they did not produce hyaline cartilage. CLINICAL RELEVANCE: Periodical intra-articular injections of platelet concentrate after microfractures may improve cartilage repair and prevent further degenerative changes
    corecore