324,405 research outputs found
The effect of puberty on insulin resistance in obese children.
No full textJ Endocrinol Invest. 2009 May;32(5):401-5.
The effect of puberty on insulin resistance in obese children.
Pilia S, Casini MR, Foschini ML, Minerba L, Musiu MC, Marras V, Civolani P, Loche
S.
Pediatric Endocrinology Unit, Microcitemico Hospital, ASL Cagliari, Cagliari,
Italy.
OBJECTIVE: Insulin resistance (IR) increases during puberty in normal children.
IR is the first adverse metabolic event of obesity, and the marker of the
metabolic syndrome. We aimed to study the effect of puberty on IR in obese and
normal-weight children.
DESIGN: Cross-sectional evaluation of fasting glucose, insulin concentrations,
and homeostasis model assessment of IR (HOMA-IR) in obese and control children
throughout puberty.
PATIENTS AND METHODS: We recruited 424 obese children (207 pre-pubertal and 217
pubertal divided in Tanner stages 2-3, 4, and 5) and estimated IR using the
HOMA-IR index. Data were compared to those obtained in 123 healthy normal-weight
children (40 pre-pubertal and 83 pubertal divided in Tanner stages 2-3, 4, and
5).
RESULTS: In the obese children mean HOMA-IR increased progressively across Tanner
stages, and was significantly higher in all groups (pre-pubertal and Tanner
stages 2-3, 4, and 5) of obese than in control children. HOMA-IR was
significantly correlated with BMI.
CONCLUSIONS: HOMA-IR in obese children increases at puberty more than in
normal-weight children and does not return to pre-pubertal values at the end of
puberty.
PMID: 19794287 [PubMed - indexed for MEDLINE
A note on a class of 4th order hyperbolic problems with weak and strong damping and superlinear source term
No full textIn this paper we study a initial-boundary value problem for 4th order hyperbolic equations with weak and strong damping terms and superlinear source term. For blow-up solutions a lower bound of the blow-up time is derived. Then we extend the results to a class of equations where a positive power of gradient term is introduced
Decay in chemotaxis systems with a logistic term
No full textThis paper is concerned with a general fully parabolic Keller-Segel system, defined in a convex bounded and smooth domain Ω of RN , for N ∈ {2, 3}, with coefficients depending on the chemical concentration, perturbed by a logistic source and endowed with homogeneous Neumann boundary conditions. For each space dimension, once a suitable energy function in terms of the solution is defined, we impose proper assumptions on the data and an exponential decay of such energies is established
Treatment of Facet Joints
No full textLumbar zygapophysial joints are also called “facet joints” They are often cause of chronic back pain because of rich innervation of the articular structures. In 1933, Ghormley named the spectrum of symptoms arising from its pathological involvement as “facet joint syndrome” (FCS).FCS represents 15% of chronic pain in the lower back. It is characterized by joint pain which is usually insidious in its onset and which may derive from almost any structure in the zygapophysial joints (fibrous capsule, synovial membrane, hyaline cartilage, tendons, bone) due to mechanical or inflammatory stimulation of nociceptors. Standard treatments for pain in lumbar facet joints are mainly intra-articular injections of corticosteroids and radiofrequency denervation (RFD) of the medial branches which innervate the zygapophysial joint. We review here the anatomy and physiology of the lumbar zygapophysial joints as well as diagnostic tools and treatments
Lifespan for solutions to 4-th order hyperbolic systems with time dependent coefficients
No full textWe study blow-up solutions of a nonlinear hyperbolic system of fourth order with time dependent coefficients under Dirichlet or Navier boundary conditions. We prove that under some restrictions on the data there exists a safe interval of existence of the solution and a lower bound of the lifespan is derived. The results are extended to a more general class of systems, where powers of the gradient of the solution are introduced. The proofs are based on some inequalities and coupled estimates techniques
Blow-up time estimates in nonlocal reaction-diffusion systems under various boundary conditions
No full textThis paper deals with the question of blow-up of solutions to nonlocal reaction-diffusion systems under various boundary conditions. Specifically, conditions on data are introduced to avoid the blow-up of the solution, and when the blow-up occurs, explicit lower and upper bounds of blow-up time are derived
Nuovo Realismo / Postmodernismo. Dibattito aperto fra architettura e filosofia. Coordinamento e organizzazione scientifica del Convegno Nazionale, Roma 28-29 Ottobre 2014
No full textCon riferimento al dibattito aperto in campo architettonico dal nuovo realismo di Maurizio Ferraris, il convegno ha inteso proporre un confronto su alcuni dei presupposti che hanno indotto a pensare a "un punto di svolta". Oggi le necessità reali - scrive Ferraris - "non sopportano di essere ridotte a interpretazioni", a quelle traduzioni-tradimenti di cui il postmodernismo (anche architettonico) sarebbe manifestazione eloquente. Ma il postmodernismo può dirsi anti-realista? E l'architettura, in quanto "oggetto sociale" ed esito di un progetto in vista di un miglioramento delle condizioni esistenti, non è opera di una continua attività ermeneutica, piuttosto che semplice rispecchiamento estetico della realtà? Sono queste alcune delle molteplici questioni poste dal convegno, il cui confronto dell'architettura con la filosofia non attende risposte certe, piuttosto l'apertura di nuovi orizzonti epistemologici e operativi. Il convegno si è svolto a Roma presso l'Aula magna di Fontanella Borghese della Facoltà di Architettura Sapienza Università di Roma, nei giorni 28-29 Ottobre 2014. Vi hanno partecipato (nell'ordine delle relazioni): M. Ferraris, P. Belfiore, C. Sini, S. Malcovati, R. Causarano, R. Secchi, F. Purini, E. Rocca, G. Durbiano, R. Capozzi, H. Hohenegger, M. Dezzi Bardeschi, G. Scotto, G. Strappa, A. Saggio, R. Palaia, R. Pavia, P. Mascilli Migliorini. Responsabile scientifico: Paola Gregory; Coordinamento scientifico: Paola Gregory, Cristina Marras, Stefano Catucci; Segreteria organizzativa: Saverio Massaro; Postproduzione e montaggio video: LaMa_Laboratorio Multimediale DiAP. Annunciato sul "Corriere della Sera", Mercoledì 15 Ottobre 2014, p. 45 (cultura), il convegno ha avuto risonanza nazionale e alcune recensioni. In particolare: R. Capozzi, Nuovo Realismo/Postmodernismo, un dibattito aperto: architettura e filosofia, in "Ananke", n. 74, Gennaio 2015, pp. 152-154; A. Riciputo, L'architettura della verità tra realtà e interpretazione, in "L'industria delle costruzioni", n. 442, marzo-aprile 2015, pp. 106-107. Gi Atti del convegno sono stati pubblicati nel 2016 da Officina Edizioni (cfr. la scheda su IRIS: ID:114981)
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