1,721,437 research outputs found
Optimized design and analysis of an FSK coherent optical transmission system by means of TOPSIM simulation package
No full text
Immunopathogenesis of psoriasis and psoriatic arthritis and pharmacological perspectives
No full textPolarisation independent detection by synchronous intra-bit polarisation switching in optical coherent systems
No full textHuman basophil releasability. VI. Changes in basophil releasability in patients with allergic rhinitis or bronchial asthma.
No full textDifferential roles for triglyceride and phospholipid pools of arachidonic acid in human lung macrophages.
No full textBEM and FEM approaches to the analysis of negative skin friction on piles
No full textNegative skin friction (NSF) may be a relevant problem in the design of piles in soft soils, when significant areas around the piles are loaded at the ground surface. The downdrag on piles is traditionally evaluated by reversing a part of the shaft resistance in an applied load and considering it in the evaluation of a safety factor against a bearing capacity failure. Such an approach is totally inadequate, because NSF is actually a problem of soil-pile interaction. Two methods of analysis of a pile subjected to both an external load and NSF are presented: Boundary Element Method (BEM) and Finite Element Method (FEM). The former method is based on a BEM approach and concentrates non-linearity effects at the pile-soil interface while the latter is a FEM approach using the package PLAXIS 2D. The accuracy of the methods is checked back analysing a well-documented case history of bored piles in soft soils
Cardiac Mast Cells: Underappreciated Immune Cells in Cardiovascular Homeostasis and Disease. (VARRICCHI PRIMO AUTORE E AUTORE CORRISPONDENTE)
No full textMast cells are multifarious immune cells with complex roles in tissue homeostasis and disease. They produce a plethora of mediators that play roles in inflammation, angiogenesis, lymphangiogenesis, and tissue remodeling. Recent insights into the heterogeneity of cardiac mast cell (CMC) subpopulations have renewed interest in their functional diversity in homeostasis and disease. They are located within the human heart in the myocardium, in atherosclerotic plaques, in the aortic valve, and in close proximity to nerves. Their plasticity enables different and even opposite functions in response to changing tissue contexts. These characteristics render CMCs intriguing, with a dichotomous role in protecting against, or accelerating, cardiovascular diseases. Future work should aim to identify CMC subsets, which could reveal novel therapeutic opportunities for cardiovascular disorders
- …
