1,720,981 research outputs found
HIGH PREVALENCE OF CELIAC DISEASE AND AUTOIMMUNE THYROIDITIS IN CHILDREN AND ADOLESCENTS WITH TYPE 1 DIABETES MELLITUS FROM NORTHERN SARDINIA
No full textPrevalence of subclinical neuropathy in Northern Sardinian adolescents with type 1 diabetes: results of an electrophysiological and clinical screening
No full textIntroduction. Diabetic neuropathy (DN) is a common complication of type 1 diabetes (T1DM). DN may affect both the peripheral and autonomic nervous system and is classified on the basis of the site of the lesion, type of nervous fibres involved, and presence of clinical signs and/or electrophysiological abnormalities. The pathogenesis of DN is still unclear, but several mechanisms are believed to play a role: ischemic damage, the metabolic effects of hyperglycemia, autoimmunity. Methods. In order to assess the prevalence of neuropathy we evaluated by means of clinical and electrophysiological examination 53 patients from Northern Sardinia, affected by T1DM. Results. Electrophysiological signs of neurological impairment were observed in 38 of them. A significant positive correlation between electrophysiological abnormalities, duration of diabetes and levels of glycated haemoglobin was found. Discussion. This preliminary study showed that subclinical neurological impairment is a common complication in patients with T1DM. The presence of autoantibodies to autonomic nervous tissue structures at the onset of the disease, their reduction along with a good metabolic control and their reappearance with the neurological involvement, support the hypothesis of an autoimmune condition. Investigations on the immunological patterns of our patients are scheduled to try to better assess the pathogenesis of DN
NEUROPATIA AUTONOMICA SUBCLINICA IN ADOLESCENTI CON DIABETE MELLITO TIPO 1: RISULTATI PRELIMINARI DI UNO SCREENING CONDOTTO CON UN RILEVATORE AUTOMATICO DELLA RISPOSTA RIFLESSA CARDIOVASCOLARE (CARDIONOMIC)
No full textPREVALENZA DELLA CELIACHIA E DELLA TIROIDITE AUTOIMMUNE IN BAMBINI ED ADOLESCENTI CON DIABETE DI TIPO 1 DELLA SARDEGNA SETTENTRIONALE
No full textCORSO DI VELA E CAMPO SCUOLA PER UN GRUPPO DI ADOLESCENTI DIABETICI E CELIACI: NUOVA ESPERIENZA EDUCATIVA
No full textPROGETTO DI EDUCAZIONE SANITARIA E FORMAZIONE:” IL BAMBINO DIABETICO E CELIACO A SCUOLA”
No full textHEALTH EDUCATION PROGRAMS FOR SCHOOLTEACHERS AND CATERERS: A NEW APPROACH AIMED TO REDUCE THE PSYCOSOCIAL BURDEN OF CELIAC DISEASE AND TYPE 1 DIABETES MELLITUS
No full textSeroprevalence of Helicobacter pylori in children with type 1 diabetes mellitus in Sardinia
No full textA few studies have reported an increased prevalence of Helicobacter pylori (HP) infection in diabetic subjects, which may be one of the causes of gastrointestinal symptoms and chronic atrophic gastritis frequently seen in diabetes of long duration. We determined the prevalence of HP infection in children and adolescents with Type 1 diabetes mellitus (T1DM) in the area of Sassari (northern Sardinia, Italy), which is characterized by an ethnically homogenous population at high risk of T1DM. HP IgG and IgA titres were measured in 138 patients with T1DM and 138 age-matched healthy controls. The percentage of infected subjects did not differ between T1DM patients (29.7%) and controls (32.6%). Globally, infected subjects were more than I yr older (13.0 +/- 2.7 yr) than non-infected ones (11.8 +/- 2.9 yr), independently of the presence of T1DM; in most HP-positive subjects infection was asymptomatic, and only 2 subjects in each group reported clinically relevant symptoms. HP-positive and HP-negative diabetic patients had the same duration of the disease (5.6 +/- 3.5 vs 5.5 +/- 3.6 yr) and received very similar doses of insulin (0.94 +/- 0.27 vs 0.96 +/- 0.4 IU/kg/d), whereas mean HbA(1c) was significantly lower in HP-positive patients (7.8 +/- 1.6 % vs 8.6 +/- 1.7 %, p=0.02). We conclude that the prevalence of HP infection is not higher in Sardinian children with T1DM as compared to controls of similar age, and the overall clinical impact of HP infection in terms of gastrointestinal symptoms and diabetic control seems to be low. (C) 2002, Editrice Kurtis. Z9 4A few studies have reported an increased prevalence of Helicobacter pylori (HP) infection in diabetic subjects, which may be one of the causes of gastrointestinal symptoms and chronic atrophic gastritis frequently seen in diabetes of long duration. We determined the prevalence of HP infection in children and adolescents with Type 1 diabetes mellitus (T1DM) in the area of Sassari (northern Sardinia, Italy), which is characterized by an ethnically homogenous population at high risk of T1DM. HP IgG and IgA titres were measured in 138 patients with T1DM and 138 age-matched healthy controls. The percentage of infected subjects did not differ between T1DM patients (29.7%) and controls (32.6%). Globally, infected subjects were more than 1 yr older (13.0 ± 2.7 yr) than non-infected ones (11.8 ± 2.9 yr), independently of the presence of T1DM; in most HP-positive subjects infection was asymptomatic, and only 2 subjects in each group reported clinically relevant symptoms. HP-positive and HP-negative diabetic patients had the same duration of the disease (5.6±3.5 vs 5.5±3.6 yr) and received very similar doses of insulin (0.94±0.27 vs 0.96±0.4 IU/kg/d), whereas mean HbA1c was significantly lower in HP-positive patients (7.8±1.6% vs 8.6±1.7%, p=0.02). We conclude that the prevalence of HP infection is not higher in Sardinian children with T1DM as compared to controls of similar age, and the overall clinical impact of HP infection in terms of gastrointestinal symptoms and diabetic control seems to be low
Parametri di crescita e stato di vitamina D in bambini affetti da Beta thalassemia major
No full text“IL BAMBINO DIABETICO E CELIACO A SCUOLA”: INTERVENTO FORMATIVO-INFORMATIVO
No full textConferenza Nazionale di Promozione ed Educazione alla Salute.- Gesamtstaatliche Tagung im Bereich der Gesundheitsforderung und –erziehung. Bolzano 3-5 Ottobre 2002. Abstract delle comunicazioni scientifiche
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