11 research outputs found
QUARTER OF A CENTURY ON FROM THE SOVIET ERA: REFLECTIONS ON RUSSIAN DOCTRINAL RESPONSES TO THE ANNEXATION OF CRIMEA
No full text
Book review: Lauri Mälksoo, Russian Approaches to International Law, Oxford University Press, Oxford: 2015
No full textReview of a book: Lauri Mälksoo, Russian Approaches to International Law, Oxford University Press, Oxford: 201
Execução das decisões da Corte Europeia de Direitos Humanos na Rússia : avanços recentes e desafios atuais
Full text linkPublicado em português, espanhol e inglêsTítulo em espanhol: Ejecución de las sentencias del Tribunal Europeo de Derechos Humanos en Rusia: desarrollos recientes y desafíos actuales. -- Título em inglês: Enforcement of the judgments of the European Court of Human Rights in Russia: recent developments and current challengesApresenta uma breve visão geral da abordagem da Corte EDH aos remédios judiciais e da estrutura de supervisão da execução de suas decisões pelos Estados-Membros do Conselho Europeu. Examina os problemas específicos que a Rússia encara com respeito às execuções das decisões da Corte EDH tanto no que tangem às medidas individuais quanto às gerais, assim como as conquistas do país nesse sentido
The Case of Crimea in the Light of International Law: Its Nature and Implications
Full text linkIn March 2015, the Polish Academy of Science, the Institute of Law Studies, and the Centre for Polish-Russian Dialogue held a conference entitled The Case of Crimea in the Light of International Law: Its Nature and Implications. The conference took place against the backdrop of the first anniversary of Crimea’s ‘annexation’ / ‘reunification’2 by Russia, providing an opportunity for international legal scholars to discuss the legality of these events.Over two days, the conference saw around 35 presented papers on issues following five general themes: self-determination and secession; use of force, aggression and armed attack; the international community’s response to the situation in Crimea; non-recognition of unlawful situations; and international state and individual responsibility in the case of Crimea.The invited academics and practitioners who spoke at the conference came from Austria, Belarus, Bulgaria, France, Germany, Italy, Japan, Poland, Russia, Switzerland, The Netherlands, Ukraine, UK and USA.This review will explore selected presentations on the key issues of selfdetermination, secession, use of force and State responsibility
QUARTER OF A CENTURY ON FROM THE SOVIET ERA: REFLECTIONS ON RUSSIAN DOCTRINAL RESPONSES TO THE ANNEXATION OF CRIMEA
Full text linkThe article is intended to give a reader a broader view of the post-Crimean academic discussion within Russia. The justifications offered by Russia for its actions in Crimea in 2014 were met with scepticism by the international community and international lawyers across various jurisdictions. Among Russian international legal scholars there were almost no critical voices willing to assess Crimea’s annexation as at least questionable under international law. Rather, these scholars, in their overwhelming majority, spoke or wrote on the matter in feverish defence of Russia’s actions. Some international scholars who study “Russian” approaches to international law or come across them aspart of their research seem prepared to justify the striking unity of perspective among Russian academic international lawyers by reference to the historically authoritarian nature of the Russian state. This article counters arguments of such would-be deference, suggesting that Russian academia be looked at by reference to the emerging standard of international legal profession
Expression profiles of acute lymphoblastic and myeloblastic leukemias with ALL-1 rearrangements
Full text linkThe ALL-1 gene is directly involved in 5-10% of acute lymphoblastic leukemias (ALLs) and acute myeloid leukemias (AMLs) by fusion to other genes or through internal rearrangements. DNA microarrays were used to determine expression profiles of ALLs and AMLs with ALL-1 rearrangements. These profiles distinguish those tumors from other ALLs and AMLs. The expression patterns of ALL-1-associated tumors, in particular ALLs, involve oncogenes, tumor suppressors, antiapoptotic genes, drug-resistance genes, etc., and correlate with the aggressive nature of the tumors. The genes whose expression differentiates between ALLs with and without ALL-1 rearrangement were further divided into several groups, enabling separation of ALL-1-associated ALLs into two subclasses. One of the groups included 43 genes that exhibited expression profiles closely linked to ALLs with ALL-1 rearrangements. Further, there were evident differences between the expression profiles of AMLs in which ALL-1 had undergone fusion to other genes and AMLs with partial duplication of ALL-1. The extensive analysis described here pinpointed genes that might have a direct role in pathogenesis
Small molecule RITA binds to p53, blocks p53–HDM-2 interaction and activates p53 function in tumors
No full textБезнравственная правда против неправдивой морали? Попытки трактовать права и условные свободы сексуальной ориентации в свете международных обязательств России
No full textThe recently adopted Russian federal legislation provides for imposition of the so-called ‘administrative’ sanctions for dissemination of any information regarding issues related to ‘social equality’ of diverse sexual orientations or gender identities ‘among minors’ for certain purposes (listed in the relevant provision). Under the new laws, such conduct qualifies as an administrative offence. In parallel with the aforementioned amendments, Art. 127 of the Family Code of Russian Federation was modified to prohibit adoptions by married same-sex couples and unmarried citizens of any state where homosexual marriage is permitted.The present article is written in the attempt to explore whether the recent Russian legislation is compatible with international standards of human rights protection deriving from the International Covenant on Civil and Political Rights and the European Convention on Human Rights and the relevant jurisprudence of international bodies. Is there any possibility to justify the restrictive laws under international law, bearing in mind the support of this legislative trend by the majority of the Russian population?Недавно вступившее в силу российское федеральное законодательство предусматривает наложение так называемых «административных» санкций за распространение любой информации относительно «социального равенства» или нетрадиционной сексуальной ориентации или «полового самоопределения личности» среди меньшинств для определенных целей (перечислены в соответствующем Положении). В соответствии с новыми законами, такое поведение расценивается как административное правонарушение. Одновременно с вышеупомянутыми поправками, ст. 127 Семейного Кодекса Российской Федерации была изменена с целью запретить усыновление детей женатыми однополыми парами а так же не состоящими в браке гражданами любого государства, где однополые браки разрешены.В данной статье авторы пытаются исследовать совместимо ли недавнее русское законодательство с международными стандартами защиты прав человека, закрепленными в Международном Пактео Гражданских и Политических правах и Европейской конвенции о защите прав человека и основных свобод и соответствующими правовыми актами международных организаций. Есть ли возможность оправдать строгие законы в соответствии с международным правом, учитывая поддержку этой законодательной тенденции большинством российского населения
MRE11 facilitates the removal of human topoisomerase II complexes from genomic DNA
Full text linkTopoisomerase II creates a double-strand break intermediate with topoisomerase covalently coupled to the DNA via a 5'-phosphotyrosyl bond. These intermediate complexes can become cytotoxic protein-DNA adducts and DSB repair at these lesions requires removal of topoisomerase II. To analyse removal of topoisomerase II from genomic DNA we adapted the trapped in agarose DNA immunostaining assay. Recombinant MRE11 from 2 sources removed topoisomerase IIalpha from genomic DNA in vitro, as did MRE11 immunoprecipitates isolated from A-TLD or K562 cells. Basal topoisomerase II complex levels were very high in A-TLD cells lacking full-length wild type MRE11, suggesting that MRE11 facilitates the processing of topoisomerase complexes that arise as part of normal cellular metabolism. In K562 cells inhibition of MRE11, PARP or replication increased topoisomerase IIalpha and beta complex levels formed in the absence of an anti-topoisomerase II dru
