1,721,255 research outputs found
Effectiveness of Benralizumab in severe eosinophilic asthma: Distinct sub‐phenotypes of response identified by cluster analysis by Di Bona et al.
No full textNasal nitric oxide as biomarker in the evaluation and management of chronic rhino-sinusitis with nasal polyposis
No full textOsservazioni fitosociologiche su aspetti di vegetazione a Quercus ilex di Monte Sparagio (Trapani)
No full textPhytosociological observation on some aspect of Quercus ilex vegetation located on the Monte Sparagio (Trapani- N-NW Sicily) – The study of some Quercus ilex residual formations occurring on the Monte Sparagio in the Trapani district (NW Sicily) is presented here. These formations testify that in the past thermophilous Quercus ilex woods were widespread along the littoral mountains facing to Tyrrhenian sea. They are assigned to the Rhamno alaterni-Quercetum ilicis pistacietosum terebinthi
Exhaled nitric oxide after inhalation of isotonic and hypotonic solutions
No full textUp to few years ago nitric oxide (NO), produced by several cells in the respiratory tract, was considered only a noxious gaseous component of environmental pollution it is involved in important biological roles including the regulation of blood flow, platelet function, neurotransmission and immunity. NO measurement from exhaled air has been suggested as a useful tool in monitoring inflammatory diseases in the human airways. NO detected in the airways may be influenced by several direct and indirect challenges, such as inhalation of solutions at different osmolarity. After a short review of NO chemical-physical property, production and physiology, the potential role of modifications of airway environment (osmolarity, pH, active and passive smoke) on mechanisms of NO synthesis and the relative physiopathological implications will be discussed
Clinical and Inflammatory Phenotyping: Can Electronic Nose and NMR-based Metabolomics Work at the Bedside?
No full textElectronic nose (eNose) and nuclear magnetic resonance (NMR)-based metabolomics seem to be able to identify metabolic and inflammatory profiles in patients with chronic obstructive diseases. The hypothesis arises from three recent studies using two different methods in patients with asthma and chronic obstructive pulmonary diseases (COPD), opening promising diagnostic perspectives. The possibility that the use of eNose and NMR-based metabolomics might provide clinical/inflammatory characteristics is intriguing. This might classify specific phenotypes of chronic airway disease regardless of the diagnosis asthma or COPD, therefore suggesting therapeutical targets for a personalized respiratory medicine through more efficient “tailored” strategies
Metabolomics of chronic obstructive pulmonary disease and obstructive sleep apnea syndrome: a comment
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