1,720,959 research outputs found

    Surgical Outcomes for Patients with Turner Syndrome.

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    To the Editor, We read with great interest the report by Cramer et al. [3] on the spectrum of congenital heart disease (CHD) and outcomes after surgical repair in children with Turner syndrome (TS). In their retrospective single-center review, the authors showed that although patients with TS undergoing aortic arch repair have a longer operative and postoperative course, their outcomes appear similar to those of non-TS subjects. Recent papers [1, 8] have identified a vasculopathy in TS patients involving intimal and medial thickening of large arteries that can lead to progressive aortic dilation, dissection, and even rupture. These arterial characteristics can explain the friability of the aortic wall, with higher risk of hemorrhages at surgery [2, 9] and after stent implantation [4] as described in the literature. It is noteworthy that although these findings constitute a potential increased risk of surgical complications, no patients reported by Cramer et al. [3] died due to the intervention, and only one patient required early reintervention for recoarctation. In line with these results, we observed the same outcome in our small cohort of six TS patients who underwent surgical coarctation repair. No surgical mortality or morbidity occurred, and during the long-term follow-up period, none of the patients had a residual systolic pressure gradient higher than 10 mmHg detected by serial echocardiography. Currently, overall data [2, 3, 9] suggest that the association with TS is not a specific risk factor for mortality among patients who have undergone surgery for aortic coarctation. However, specific caution should be observed relative to the possibility of perioperative bleeding and “a more challenging early postoperative course” [3]. Moreover, as reported in our recent study [10], it is important to consider that these patients can have not only cardiovascular malformations but also an impaired cardiopulmonary response to exercise and impaired systolic and diastolic function of the left ventricle. These further findings can be considered a specific cardiac phenotype of TS subjects and may represent additional risk factors for perioperative complications or for postoperative morbidity. Studies increasingly report on perioperative outcomes for patients with CHD and genetic syndromes such as trisomy 21 and del 22q11.2 with the aim of detecting the impact not only of specific anatomic cardiac patterns but also of extracardiac anomalies on the intensive care unit stay and surgical results [6, 7]. We underscore the necessity of recognizing specific surgical risk factors for syndromic patients with CHD that can lead to the preparation of specific diagnostic and perioperative protocols to reduce operative mortality and morbidity. The stratification of risks based on genotyping is an encouraging perspective in cardiovascular medicine, and the shift from a genotype–phenotype correlation toward a genotype prognosis paradigm currently is available also in pediatric cardiology [5]

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Author Index

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    koamabayili/VECTRON-author-checklist: VECTRON author checklist

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    We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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