3 research outputs found
Genes in the <i>SREB</i> regulon involved with iron acquisition and homeostasis.
No full text<p><b>(A)</b> Heat map of genes in the <i>SREB</i> regulon involved with siderophore biosynthesis (orange text for the siderophore biosynthetic gene cluster and red text for ferricrocin biosynthetic genes), siderophore transport (green text), and ferric reduction (blue text). <b>(B)</b> Schematic of putative siderophore biosynthetic gene cluster. Locus number (BDBG #) for genes in the <i>Blastomyces</i> genome database at the Broad Institute (<a href="http://www.broadinstitute.org/" target="_blank">www.broadinstitute.org</a>) is listed below the coding region of each gene. <b>(C)</b> Quantitative real-time PCR analysis of yeast (37°C) for a subset of genes in the <i>SREB</i> regulon involved with iron acquisition and homeostasis. The results were averaged from 2 experiments. <b>(D)</b> Reverse-phase high-pressure liquid chromatography analysis for ferricrocin, an intracellular storage siderophore, in wild-type and <i>SREB</i>∆ yeast.</p
Chromatin immunoprecipitation with quantitative real-time PCR (ChIP-qPCR).
No full text<p><b>(A)</b> Enrichment for binding of SREB-3xHA to promoter regions containing GATA binding motifs in <i>B</i>. <i>dermatitidis</i> yeast at 37°C. <b>(B)</b> Enrichment binding of SREB-3xHA to promoter regions containing GATA binding motifs in <i>B</i>. <i>dermatitidis</i> cells at 48-hrs following a drop in temperature from 37°C to 22°C. ChIP-qPCR was performed using SREB that was engineered to contain a C-terminal 3x-hemagglutinin tag. Integration of gene expression microarray data with genome-wide GATA motif analysis was used to identify putative GATA transcription factor binding sites. All genes analyzed were differentially expressed and contained a GATA motif (ATC-w-gAta-a or A/T-GATA-A/G) in the upstream promoter. For <i>MIRB</i>, the upstream motif in strain 26199 was ATC-A-GATT-A, whereas in other strains including SLH14081, ER-3, and ATCC 18188, the motif was ATC-A-GATA-A. BDBG is the locus number for genes in the <i>B</i>. <i>dermatitidis</i> genome database at the Broad Institute (<a href="http://www.broadinstitute.org/" target="_blank">www.broadinstitute.org</a>).</p
Constraints on Models of the Higgs Boson with Exotic Spin and Parity using Decays to Bottom-Antibottom Quarks in the Full CDF Data Set
No full textCitation: Aaltonen, T., Amerio, S., Amidei, D., Anastassov, A., Annovi, A., Antos, J., . . . Collaboration, C. D. F. (2015). Constraints on Models of the Higgs Boson with Exotic Spin and Parity using Decays to Bottom-Antibottom Quarks in the Full CDF Data Set. Physical Review Letters, 114(14), 9. doi:10.1103/PhysRevLett.114.141802A search for particles with the same mass and couplings as those of the standard model Higgs boson but different spin and parity quantum numbers is presented. We test two specific alternative Higgs boson hypotheses: a pseudoscalar Higgs boson with spin-parity J(P) = 0(-) and a gravitonlike Higgs boson with J(P) = 2(+), assuming for both a mass of 125 GeV/c(2). We search for these exotic states produced in association with a vector boson and decaying into a bottom-antibottom quark pair. The vector boson is reconstructed through its decay into an electron or muon pair, or an electron or muon and a neutrino, or it is inferred from an imbalance in total transverse momentum. We use expected kinematic differences between events containing exotic Higgs bosons and those containing standard model Higgs bosons. The data were collected by the CDF experiment at the Tevatron proton-antiproton collider, operating at a center-of-mass energy of root s = 1.96 TeV, and correspond to an integrated luminosity of 9.45 fb(-1). We exclude deviations from the predictions of the standard model with a Higgs boson of mass 125 GeV/c(2) at the level of 5 standard deviations, assuming signal strengths for exotic boson production equal to the prediction for the standard model Higgs boson, and set upper limits of approximately 30% relative to the standard model rate on the possible rate of production of each exotic state.Additional Authors: Badgett, W.;Bae, T.;Barbaro-Galtieri, A.;Barnes, V. E.;Barnett, B. A.;Barria, P.;Bartos, P.;Bauce, M.;Bedeschi, F.;Behari, S.;Bellettini, G.;Bellinger, J.;Benjamin, D.;Beretvas, A.;Bhatti, A.;Bland, K. R.;Blumenfeld, B.;Bocci, A.;Bodek, A.;Bortoletto, D.;Boudreau, J.;Boveia, A.;Brigliadori, L.;Bromberg, C.;Brucken, E.;Budagov, J.;Budd, H. S.;Burkett, K.;Busetto, G.;Bussey, P.;Butti, P.;Buzatu, A.;Calamba, A.;Camarda, S.;Campanelli, M.;Canelli, F.;Carls, B.;Carlsmith, D.;Carosi, R.;Carrillo, S.;Casal, B.;Casarsa, M.;Castro, A.;Catastini, P.;Cauz, D.;Cavaliere, V.;Cerri, A.;Cerrito, L.;Chen, Y. C.;Chertok, M.;Chiarelli, G.;Chlachidze, G.;Cho, K.;Chokheli, D.;Clark, A.;Clarke, C.;Convery, M. E.;Conway, J.;Corbo, M.;Cordelli, M.;Cox, C. A.;Cox, D. J.;Cremonesi, M.;Cruz, D.;Cuevas, J.;Culbertson, R.;d'Ascenzo, N.;Datta, M.;de Barbaro, P.;Demortier, L.;Deninno, M.;D'Errico, M.;Devoto, F.;Di Canto, A.;Di Ruzza, B.;Dittmann, J. R.;Donati, S.;D'Onofrio, M.;Dorigo, M.;Driutti, A.;Ebina, K.;Edgar, R.;Elagin, A.;Erbacher, R.;Errede, S.;Esham, B.;Farrington, S.;Ramos, J. P. F.;Field, R.;Flanagan, G.;Forrest, R.;Franklin, M.;Freeman, J. C.;Frisch, H.;Funakoshi, Y.;Galloni, C.;Garfinkel, A. F.;Garosi, P.;Gerberich, H.;Gerchtein, E.;Giagu, S.;Giakoumopoulou, V.;Gibson, K.;Ginsburg, C. M.;Giokaris, N.;Giromini, P.;Glagolev, V.;Glenzinski, D.;Gold, M.;Goldin, D.;Golossanov, A.;Gomez, G.;Gomez-Ceballos, G.;Goncharov, M.;Lopez, O. G.;Gorelov, I.;Goshaw, A. T.;Goulianos, K.;Gramellini, E.;Grosso-Pilcher, C.;Group, R. C.;da Costa, J. G.;Hahn, S. R.;Han, J. Y.;Happacher, F.;Hara, K.;Hare, M.;Harr, R. F.;Harrington-Taber, T.;Hatakeyama, K.;Hays, C.;Heinrich, J.;Herndon, M.;Hocker, A.;Hong, Z.;Hopkins, W.;Hou, S.;Hughes, R. E.;Husemann, U.;Hussein, M.;Huston, J.;Introzzi, G.;Iori, M.;Ivanov, A.;James, E.;Jang, D.;Jayatilaka, B.;Jeon, E. J.;Jindariani, S.;Jones, M.;Joo, K. K.;Jun, S. Y.;Junk, T. R.;Kambeitz, M.;Kamon, T.;Karchin, P. E.;Kasmi, A.;Kato, Y.;Ketchum, W.;Keung, J.;Kilminster, B.;Kim, D. H.;Kim, H. S.;Kim, J. E.;Kim, M. J.;Kim, S. H.;Kim, S. B.;Kim, Y. J.;Kim, Y. K.;Kimura, N.;Kirby, M.;Knoepfel, K.;Kondo, K.;Kong, D. J.;Konigsberg, J.;Kotwal, A. V.;Kreps, M.;Kroll, J.;Kruse, M.;Kuhr, T.;Kurata, M.;Laasanen, A. T.;Lammel, S.;Lancaster, M.;Lannon, K.;Latino, G.;Lee, H. S.;Lee, J. S.;Leo, S.;Leone, S.;Lewis, J. D.;Limosani, A.;Lipeles, E.;Lister, A.;Liu, H.;Liu, Q.;Liu, T.;Lockwitz, S.;Loginov, A.;Lucchesi, D.;Luca, A.;Lueck, J.;Lujan, P.;Lukens, P.;Lungu, G.;Lys, J.;Lysak, R.;Madrak, R.;Maestro, P.;Malik, S.;Manca, G.;Manousakis-Katsikakis, A.;Marchese, L.;Margaroli, F.;Marino, P.;Matera, K.;Mattson, M. E.;Mazzacane, A.;Mazzanti, P.;McNulty, R.;Mehta, A.;Mehtala, P.;Mesropian, C.;Miao, T.;Mietlicki, D.;Mitra, A.;Miyake, H.;Moed, S.;Moggi, N.;Moon, C. S.;Moore, R.;Morello, M. J.;Mukherjee, A.;Muller, T.;Murat, P.;Mussini, M.;Nachtman, J.;Nagai, Y.;Naganoma, J.;Nakano, I.;Napier, A.;Nett, J.;Neu, C.;Nigmanov, T.;Nodulman, L.;Noh, S. Y.;Norniella, O.;Oakes, L.;Oh, S. H.;Oh, Y. D.;Oksuzian, I.;Okusawa, T.;Orava, R.;Ortolan, L.;Pagliarone, C.;Palencia, E.;Palni, P.;Papadimitriou, V.;Parker, W.;Pauletta, G.;Paulini, M.;Paus, C.;Phillips, T. J.;Piacentino, G.;Pianori, E.;Pilot, J.;Pitts, K.;Plager, C.;Pondrom, L.;Poprocki, S.;Potamianos, K.;Pranko, A.;Prokoshin, F.;Ptohos, F.;Punzi, G.;Fernandez, I. R.;Renton, P.;Rescigno, M.;Rimondi, F.;Ristori, L.;Robson, A.;Rodriguez, T.;Rolli, S.;Ronzani, M.;Roser, R.;Rosner, J. L.;Ruffini, F.;Ruiz, A.;Russ, J.;Rusu, V.;Sakumoto, W. K.;Sakurai, Y.;Santi, L.;Sato, K.;Saveliev, V.;Savoy-Navarro, A.;Schlabach, P.;Schmidt, E. E.;Schwarz, T.;Scodellaro, L.;Scuri, F.;Seidel, A. S.;Seiya, Y.;Semenov, A.;Sforza, F.;Shalhout, S. Z.;Shears, T.;Shepard, P. F.;Shimojima, M.;Shochet, M.;Shreyber-Tecker, I.;Simonenko, A.;Sliwa, K.;Smith, J. R.;Snider, F. D.;Song, H.;Sorin, V.;St Denis, R.;Stancari, M.;Stentz, D.;Strologas, J.;Sudo, Y.;Sukhanov, A.;Suslov, I.;Takemasa, K.;Takeuchi, Y.;Tang, J.;Tecchio, M.;Teng, P. K.;Thom, J.;Thomson, E.;Thukral, V.;Toback, D.;Tokar, S.;Tollefson, K.;Tomura, T.;Tonelli, D.;Torre, S.;Torretta, D.;Totaro, P.;Trovato, M.;Ukegawa, F.;Uozumi, S.;Vazquez, F.;Velev, G.;Vellidis, C.;Vernieri, C.;Vidal, M.;Vilar, R.;Vizan, J.;Vogel, M.;Volpi, G.;Wagner, P.;Wallny, R.;Wang, S. M.;Waters, D.;Wester, W. C.;Whiteson, D.;Wicklund, A. B.;Wilbur, S.;Williams, H. H.;Wilson, J. S.;Wilson, P.;Winer, B. L.;Wittich, P.;Wolbers, S.;Wolfe, H.;Wright, T.;Wu, X.;Wu, Z.;Yamamoto, K.;Yamato, D.;Yang, T.;Yang, U. K.;Yang, Y. C.;Yao, W. M.;Yeh, G. P.;Yi, K.;Yoh, J.;Yorita, K.;Yoshida, T.;Yu, G. B.;Yu, I.;Zanetti, A. M.;Zeng, Y.;Zhou, C.;Zucchelli, S.;Collaboration, C. D. F
