3,027 research outputs found
Corrigendum to ‘Toll-like receptors in immunity and inflammatory diseases: Past, present, and future’ [International Immunopharmacology 59 (2018) 391–412](S156757691830095X)(10.1016/j.intimp.2018.03.002)
No full textThe authors regret that the name of the author was mentioned incorrectly in the earlier version of the manuscript. It should be mentioned as Vijay Kumar. The authors would like to apologise for any inconvenience caused
Design and Analysis of Connecting Rod of Diesel Engine
No full textThe main objective of this study is to review the weight optimization and cost reduction of a connecting rod in a Diesel engine. To get the idea about designing the connecting rod, various stresses to be considered while designing the connecting rod .This has entailed performing a detailed load analysis. The most important factors that are concentrated are stress distribution and deflections. In this project the connecting rod is designed with respect to all the available constraints using advanced cad software CATIA. Later the product file is converted to .stp file format standard exchange of product file and imported to ANSYS workbench to find deformation and analytic valve with respect to the model or product definitions. A. Vijay Kumar | K. Mihir | M. Mrudul | P. Pavan Kumar "Design and Analysis of Connecting Rod of Diesel Engine" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-3 | Issue-3 , April 2019, URL: https://www.ijtsrd.com/papers/ijtsrd23182.pd
An Experimental Study of Wind Resistance and Power Consumption in MAVs with a Low-Speed Multi-Fan Wind System
No full textThis paper discusses a low-cost, open-source and open-hardware design and performance evaluation of a low-speed, multi-fan wind system dedicated to micro air vehicle (MAV) testing. In addition, a set of experiments with a flapping wing MAV and rotorcraft is presented, demonstrating the capabilities of the system and the properties of these different types of drones in response to various types of wind. We performed two sets of experiments where a MAV is flying into the wake of the fan system, gathering data about states, battery voltage and current. Firstly, we focus on steady wind conditions with wind speeds ranging from 0.5 m S-1 to 3.4 m S-1. During the second set of experiments, we introduce wind gusts, by periodically modulating the wind speed from 1.3 m S−1 to 3.4 m S−1 with wind gust oscillations of 0.5 Hz, 0.25 Hz and 0.125 Hz. The “Flapper” flapping wing MAV requires much larger pitch angles to counter wind than the “CrazyFlie” quadrotor. This is due to the Flapper's larger wing surface. In forward flight, its wings do provide extra lift, considerably reducing the power consumption. In contrast, the CrazyFlie's power consumption stays more constant for different wind speeds. The experiments with the varying wind show a quicker gust response by the CrazyFlie compared with the Flapper drone, but both their responses could be further improved. We expect that the proposed wind gust system will provide a useful tool to the community to achieve such improvements.Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Control & Simulatio
sj-docx-1-pie-10.1177_09544089221108680 - Supplemental material for Parameter optimization for enhancing tribological properties of sol–gel alumina and aluminum silicate-coated aluminum alloy: Grey–Taguchi method
No full textSupplemental material, sj-docx-1-pie-10.1177_09544089221108680 for Parameter optimization for enhancing tribological properties of sol–gel alumina and aluminum silicate-coated aluminum alloy: Grey–Taguchi method by Renjish Vijay, VN Aju Kumar, A Sadiq, Baiju Sasidharan, M Mohammed Arif and S Rani in Proceedings of the Institution of Mechanical Engineers, Part E: Journal of Process Mechanical Engineering</p
Fabrication of a Flexible UV Band-Pass Filter Using Surface Plasmon Metal-Polymer Nanocomposite Films for Promising Laser Applications
No full textWe introduce a strategy for the fabrication of silver/polycarbonate (Ag/PC) nanocomposite flexible films of (20 +/- 0.01) mu m thickness with different filling factor of surface plasmon metal using customized solution cast thermal evaporation method. Structural characterizations confirmed the good crystallinity with cubic phase of Ag nanoparticles in PC films. Moreover, the microstructural evolutions of nanocomposite films are investigated by transmission electron microscopy, which indicates that the metal fraction is in the form of fractals. Additionally, the surface plasmonic behavior of nanocomposite films has been explored in detail to examine the distribution of Ag nanoparticles in PC film by spectroscopic technique. Furthermore, the obtained transmittance spectral features of this nanocomposite film are suitable for the applications of band-pass filter at 320 nm UV range, which is highly desirable for a HeCd laser
"PERFORMANCE ASSESSMENT OF WORK EFFICIENCY OF EASY TRANSPLANTER FOR REDUCING DRUDGERY AMONG FARM WOMEN WHILE TRANSPLANTING OF TOMATO SEEDLINGS"
No full text"M. Bhavya Manjari, RVT. Balazzii Naaiik, B.V. Rajkumar, M. Swetha, P. Vijay Kumar, M. Suresh, Maloth Mohan and C. Padmaveni
Protein phosphatase 2A inhibits interferon signaling through the Jak STAT pathway and promotes hepatitis C viral replication
No full textThe first part of the work demonstrate the role of PP2A in IFN-α induced Jak-STAT1 signaling and HCV replication. We show here that PP2Ac activity is not required for IFN-α induced tyrosine phosphorylation of Jak1/Tyk2 and STAT1. In response to IFN-α induction, PP2Ac associates with Jak1/Tyk2 and STAT1. This association modulates the Jak1/Tyk2 and STAT1 tyrosine phosphorylation. However, this study shows that PP2A activity is required for the HCV replication.
The selective behavior of PP2A for Jak-STAT1 signaling pathway inhibition and promotion of HCV replication could be due to the targeted substrate selection by PP2A holoenzyme complex. In the second part of this work, attempts were made to determine the specific regulatory B subunits involved in IFN-α induced Jak-STAT1 signaling inhibition and HCV replication. We observed the inter-regulatory behavior of PP2A subunits. During the course of this study, due to unavailability of specific antibodies for various isoforms of B subunit, the aim to determine specific holoenzyme complex involved in regulation of Jak-STAT1 signaling and HCV replication was not achieved.
Further studies are required to investigate the specific B subunits and thereby holoenzyme complex responsible for IFN-α induced Jak-STAT signaling inhibition and HCV replication by PP2A
Opening Up Education
No full textExperts discuss the potential for open education tools, resources, and knowledge to transform the economics and ecology of education.Given the abundance of open education initiatives that aim to make educational assets freely available online, the time seems ripe to explore the potential of open education to transform the economics and ecology of education. Despite the diversity of tools and resources already available—from well-packaged course materials to simple games, for students, self-learners, faculty, and educational institutions—we have yet to take full advantage of shared knowledge about how these are being used, what local innovations are emerging, and how to learn from and build on the experiences of others. Opening Up Education argues that we must develop not only the technical capability but also the intellectual capacity for transforming tacit pedagogical knowledge into commonly usable and visible knowledge: by providing incentives for faculty to use (and contribute to) open education goods, and by looking beyond institutional boundaries to connect a variety of settings and open source entrepreneurs. These essays by leaders in open education describe successes, challenges, and opportunies they have found in a range of open education initiatives. They approach—from both macro and micro perspectives—the central question of how open education tools, resources, and knowledge can improve the quality of education. The contributors (from leading foundations, academic institutions, associations, and projects) discuss the strategic underpinnings of their efforts first in terms of technology, then content, and finally knowledge. They also address the impact of their projects, and how close they come to achieving a vision of sustainable, transformative educational opportunities that amounts to much more than pervasive technology.Through the support of the Carnegie Foundation for the Advancement of Teaching, an electronic version of this book is openly available under a Creative Commons license at The MIT Press Web site, http://mitpress.mit.edu. ContributorsRichard Baraniuk, Randy Bass, Trent Batson, Dan Bernstein, John Seely Brown, Barbara Cambridge, Tom Carey, Catherine Casserly, Bernadine Chuck Fong, Ira Fuchs, Richard Gale, Mia Garlick, Gerard Hanley, Diane Harley, Mary Huber, Pat Hutchings, Toru Iiyoshi, David Kahle, M. S. Vijay Kumar, Andy Lane, Diana Laurillard, Stuart Lee, Steve Lerman, Marilyn Lombardi, Phil Long, Clifford Lynch, Christopher Mackie, Anne Margulies, Owen McGrath, Flora McMartin, Shigeru Miyagawa, Diana Oblinger, Neeru Paharia, Cheryl Richardson, Marshall Smith, Candace Thille, Edward Walker, David Wile
Opening Up Education: The Collective Advancement of Education through Open Technology, Open Content, and Open Knowledge
No full textGiven the abundance of open education initiatives that aim to make educational assets freely available online, the time seems ripe to explore the potential of open education to transform the economics and ecology of education. Despite the diversity of tools and resources already available -- from well-packaged course materials to simple games, for students, self-learners, faculty, and educational institutions -- we have yet to take full advantage of shared knowledge about how these are being used, what local innovations are emerging, and how to learn from and build on the experiences of others. Opening Up Education argues that we must develop not only the technical capability but also the intellectual capacity for transforming tacit pedagogical knowledge into commonly usable and visible knowledge: by providing incentives for faculty to use (and contribute to) open education goods, and by looking beyond institutional boundaries to connect a variety of settings and open source entrepreneurs.These essays by leaders in open education describe successes, challenges, and opportunities they have found in a range of open education initiatives. They approach -- from both macro and micro perspectives -- the central question of how open education tools, resources, and knowledge can improve the quality of education. The contributors (from leading foundations, academic institutions, associations, and projects) discuss the strategic underpinnings of their efforts first in terms of technology, then content, and finally knowledge. They also address the impact of their projects, and how close they come to achieving a vision of sustainable, transformative educational opportunities that amounts to much more than pervasive technology.Contributors:Richard Baraniuk, Randy Bass, Trent Batson, Dan Bernstein, John Seely Brown, Barbara Cambridge, Tom Carey, Catherine Casserly, James Dalziel, Bernadine Chuck Fong, Richard Gale, Gerard Hanley, Diane Harley, Mary Huber, Pat Hutchings, Toru Iiyoshi, David Kahle, M. S. Vijay Kumar, Andy Lane, Diana Laurillard, Stuart Lee, Steve Lerman, Marilyn Lombardi, Phil Long, Clifford Lynch, Christopher Mackie, Anne Margulies, Owen McGrath, Flora McMartin, Shigeru Miyagawa, Diana Oblinger, Neeru Paharia, Cheryl Richardson, Marshall Smith, Candace Thille, Edward Walker, and David WileyAbout the Editors:Toru Iiyoshi is Senior Scholar and Director of the Knowledge Media Lab at the Carnegie Foundation.M. S. Vijay Kumar is Senior Associate Dean and Director of the Office of Educational Innovation and Technology at MIT
Where to Look Next: Learning Viewpoint Recommendations for Informative Trajectory Planning
No full textSearch missions require motion planning and navigation methods for information gathering that continuously replan based on new observations of the robot's surroundings. Current methods for information gathering, such as Monte Carlo Tree Search, are capable of reasoning over long horizons, but they are computationally expensive. An alternative for fast online execution is to train, offline, an information gathering policy, which indirectly reasons about the information value of new observations. However, these policies lack safety guarantees and do not account for the robot dynamics. To overcome these limitations we train an information-aware policy via deep reinforcement learning, that guides a receding-horizon trajectory optimization planner. In particular, the policy continuously recommends a reference viewpoint to the local planner, such that the resulting dynamically feasible and collision-free trajectories lead to observations that maximize the information gain and reduce the uncertainty about the environment. In simulation tests in previously unseen environments, our method consistently outperforms greedy next-best-view policies and achieves competitive performance compared to Monte Carlo Tree Search, in terms of information gains and coverage time, with a reduction in execution time by three orders of magnitude.Green Open Access added to TU Delft Institutional Repository 'You share, we take care!' - Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Learning & Autonomous Contro
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