188 research outputs found
Leonard M. Trawick Interview, 21 March 2014
No full textLeonard M. Trawick, a transplant from Alabama, describes living in Cleveland for over forty years. Trained to be an English professor, Trawick held positions at Columbia University before he came to Cleveland. He describes working at Columbia during the student unrest of the 1960s. In 1969, Trawick took a position at the newly created Cleveland State University. He relates the conditions of the school during those early years. He also has fond memories of the poetry programming that Cleveland State created in the 1970s and \u2780s. Apart from his work, Trawick mentions the various shopping areas in downtown Cleveland and closer to where he lived in Cleveland Heights. He notes the differences between Higbee\u27s and May Company by relating them to New York landmarks like Bloomingdale\u27s and Macy\u27s. He concludes by reiterating how vibrant the Cleveland literary scene was in the 1970s and \u2780s
Memo from Kerstin Ekfelt Trawick to Kathleen M. Carrick
No full textMemo from Kerstin Trawick, Director of Publications and External Affairs, to Kathleen Carrick, Director of the Law Library, regarding transcriptions of fourteen oral history interviews and accompanying materials
The Migration of African Americans to the Canadian Football League during the mid-20th Century: An Escape from Discrimination?
No full textThe institutional racial discrimination that existed in American professional team sports prior to World War II resulted in African American players effectively being barred from playing in the major professional leagues. Although the NFL color barrier did officially fall in 1946, to be quickly followed by the fall of the MLB color barrier one year later when Jackie Robinson made his debut for the Brooklyn Dodgers, these events were just the beginning of the struggles for African American athletes. Integration proceeded very slowly during the next two decades, and economists have shown that African Americans continued to suffer from a variety of forms of discriminatory treatment. However, it is the argument of this paper that the literature that examines discrimination during this era is incomplete, in that it ignores the experiences of a small, but relatively significant, group of African American football players who actually chose to leave their own country – and correspondingly leave the racially-charged environment of mid-20th century America – to head north to play professional football in the Canadian Football League (CFL). Beginning in 1946, a steady flow of African Americans began to migrate to the CFL which, at the time, was a legitimate competitor league to the NFL. This paper attempts to test a perception seemingly held by some that, by moving to Canada, African American football players were able to escape the racial injustices they often suffered in the US. This view appears to have its roots in the notion that Canada is a “gentler”, more tolerant society, without the divisive socio-political history that characterizes much of the race relations in the US. This paper tests these notions using a variety of empirical approaches. The results indicate that, while African Americans were better represented in the CFL relative to the NFL, African Americans still faced some level of entry discrimination in the CFL. In particular, African American players in the CFL outperformed their white counterparts on numerous performance dimensions, indicating the overall talent level in the CFL could have been further improved by employing an even greater number of African Americans. Additionally, the paper finds that those CFL teams that employed the highest percentage of African Americans were those teams that had the most on-field success. Finally, the paper analyzes prices of player trading cards from that era, and finds that cards of African Americans were undervalued, relative to white CFL players of equal talent.sports
Developing adaptive capacity within groundwater abstraction management systems
No full textGroundwater is a key resource for global agricultural production but is
vulnerable to a changing climate. Given significant uncertainty about future
impacts, bottom-up approaches for developing adaptive capacity are a more
appropriate paradigm than seeking optimal adaptation strategies that assume a
high ability to predict future risks or outcomes. This paper analyses the
groundwater management practices adopted at multiple scales in East Anglia, UK,
to identify wider lessons for developing adaptive capacity within groundwater
management. Key elements are (1) horizontal and vertical integration within
resource management; (2) making better use of water resources, at all scales,
which vary in space and time; (3) embedding adaptation at multiple scales (from
farm to national) within an adaptive management framework which allows
strategies and management decisions to be updated in the light of changing
understanding or conditions; (4) facilitating the ongoing formation through
collective action of local Water Abstractor Groups; (5) promoting efficient use
of scarce water resources by these groups, so as to increase their power to
negotiate over possible short-term license restrictions; (6) controlling
abstractions within a sustainable resource management framework, whether at
national (regulatory) or at local (Abstractor Group) scales, that takes account
of environmental water needs; and (7) reducing non-climate pressures which have
the potential to further reduce the availability of usable groundwater. (C) 2011
Elsevier Ltd. All rights reserved
Targeting cancer through inhibition of cathepsin B by non-peptidic small molecule thiosemicarbazones and disruption of pre-existing vasculature by colchicine-like benzosuberene analogues.
No full textCancer is a leading cause of death in men and women under in the United States and is characterized by uncontrolled cellular proliferation and migration (metastasis) which can impinge on surrounding organs, modify ordinary biological functions, and lead to death. This study focuses on two strategies for cancer therapy: targeting cathepsin B, an enzyme linked to tumor metastasis and progression, and the disruption of pre-existing tumor vasculature as a means to starve tumors of oxygen and nutrients. Cathepsin B is a cysteine protease involved in intra- and extracellular degradation of proteins. Increased expression of cathepsin B has been documented in a number of different cancers and is associated with a poor disease prognosis, and increased tumor vascularization, degradation of the extracellular matrix, invasion, and metastasis. Inhibition of cathepsin B has the potential to arrest cancer cell invasion and metastasis. In a collaborative project between the Trawick and Pinney laboratories at Baylor University, a focused synthetic library of non-peptidic, small molecule thiosemicarbazone derivatives was screened for their ability to inhibit cathepsin B activity as monitored by a fluorogenic enzyme assay. Five compounds were found to be effective inhibitors of cathepsin B in the low micromolar range, and the best four were characterized for their mode of inhibition. Kinetic analysis revealed that two of the active thiosemicarbazone compounds were time dependent, competitive, tight binding, slowly reversible inhibitors of cathepsin B. The other compounds analyzed were rapidly reversible, competitive inhibitors with KI values in the low micromolar range. Vascular disrupting agents (VDAs) are a promising class of anticancer drugs that selectively disrupt tumor vasculature. Tubulin-binding VDAs disrupt microtubule dynamics of endothelial cells lining tumor vasculature. A lead benzosuberene analogue exhibited extreme cytotoxicity against a panel of human cancer cell lines. The lead compound and several of its analogues were investigated for their ability to inhibit tubulin polymerization, bind to the colchicine binding site of tubulin as determined by a competitive radiometric binding assay and arrest human breast cancer cells in the G2/M phase of the cell cycle as indicated by flow cytometry. The results support the mechanism of action of the lead benzosuberene analogues as VDAs
A comparative study of the vocabularies of ten four year old boys and girls, and ten three and one-half year old boys and girls in the nursery school of Spelman College, Atlanta, Georgia, 1935
No full textTrawick, F. D. M.
No full textSee entry in Dale County, volume 1, page 53: https://digital.archives.alabama.gov/digital/collection/voter1867/id/134
Trawick, J. M.
No full textSee entry in Dale County, volume 1, page 35: https://digital.archives.alabama.gov/digital/collection/voter1867/id/132
Pattern coarsening in a 2D hexagonal system
No full textWe have studied the ordering dynamics of a two-dimensional system which consists of a single layer of spherical block copolymer microdomains in a thin film. We follow the annealing process after a quench from the disordered state by electron microscopy and time-lapse atomic force microscopy. At late times the orientational correlation length ξ 6 of the microdomain lattice exhibits a t 1/4 temporal power law. We compare the time evolution of the densities of dislocations, disclinations and the dislocation orientational correlation function. While most disclinations condense into dislocations and most dislocations condense into "grain boundaries", the dynamics appear to involve the interplay of disclinations and lines of dislocations. Rather than isolated grains shrinking, the most frequently observed process is the collapse of a smaller grain which resides on the boundary of two larger grains.Fil: Harrison, C.. University of Princeton; Estados UnidosFil: Angelescu, D. E.. University of Princeton; Estados UnidosFil: Trawick, M.. University of Princeton; Estados UnidosFil: Cheng, Z.. University of Princeton; Estados UnidosFil: Huse, D. A.. University of Princeton; Estados UnidosFil: Chaikin, P. M.. University of Princeton; Estados UnidosFil: Vega, Daniel Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca; Argentina. University of Princeton; Estados UnidosFil: Sebastian, J. M.. University of Princeton; Estados UnidosFil: Register, R. A.. University of Princeton; Estados UnidosFil: Adamson, D. H.. University of Princeton; Estados Unido
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