1,720,996 research outputs found

    Reductive ring opening of 2-azetidinones promoted by sodium borohydride

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    Variously substituted 2-azetidinones 3 and 4 were reacted with sodium borohydride in aqueous isopropanol giving 3-aminopropan-1,2-dioles 5 and 7. Reaction extent was dependent upon the substitution pattern in the 3- and 4-positions of the 2-azetidinone ring and revealed good correlation with carbonyl LUMO energies of starting 3. (c) 2006 Elsevier Ltd. All rights reserved

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Valorization of sea urchins waste for the development of composite biomaterials for regenerative medicine

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    Sea urchins possess peculiar anatomic/physiological adaptations in terms of specialized connective tissues (e.g. the Mutable Collagenous Tissues, MCT) and antioxidant compounds which can be exploited for biomedical applications through an eco-friendly approach. Indeed, the food waste deriving from processing of edible sea urchins (up to 90% of their mass) can still be a source of 1) MCT-derived native collagen, extracted from the peristomial membrane, which can be used to produce biomimetic collagen-made biomaterials, 2) polyhydroxynaphtoquinones (PHNQ) a class of polyphenolic with potent antioxidant properties that can be obtained by the test and the spines. By combining these molecules, we recently optimized a protocol to develop polyphenol-rich and collagen-based composite biomaterials for regenerative medicine applications, which retain both biomimetic and bioactive properties. In order to verify the suitability of the produced sea urchin-derived matrices for tissue regeneration purposes, in the present work, the composites were characterized in terms of ultrastructure (SEM), degradation kinetics (physiological and enzymatic conditions), swelling properties, water uptake, release kinetics of PHNQ and antioxidant activity (ABTS assay). Results showed that composites are ultrastructurally similar to the pure collagen-based counterpart, displaying an homogeneous porous structure without visible aggregates. Degradation kinetics and swelling test showed a significant improvement of the stability in the composites, compared to both simple collagen-based and UV-crosslinked biomaterials. Lastly, PHNQ remained absorbed to the collagen matrix where they fully retained their antioxidant activity, thus providing the biomaterial with a further functionality potentially useful in tissue repair. In conclusion, these findings show that sea urchins waste can be fully exploited to extract valuable molecules and develop innovative and multifunctional biomaterials, useful for tissue regeneration. As a future perspective, 3D bioprinting technology is under development to produce customized and green devices of marine origin

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Author Index

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    koamabayili/VECTRON-author-checklist: VECTRON author checklist

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    We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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