148 research outputs found
Quality of care indicators for head and neck cancers : the experience of the European project RARECAREnet
No full textBackground: Monitoring and improving quality of cancer care has become pivotal today. This is especially relevant for head and neck cancers since the disease is complex, it needs multi therapy, patients tend to be older, they tend to have comorbidities and limited social support. However, information on quality of care for head and neck cancers is scarce. In the context of the project "Information Network on Rare Cancers" we aimed to identify indicators of quality of care specific for the head and neck cancers management and to measure the quality of care for head and neck cancers in different EU Member States. Methods: We defined indicators of quality of care for head and neck cancers based on a multidisciplinary and expert-based consensus process at a European level. To test the proposed indicators, we performed an observational population-based retrospective study in four countries (Ireland, Italy, Netherlands, and Slovenia) in the years 2009-2011. Results: The main quality indicators identified are: availability of formalized multidisciplinary team, participation in clinical and translational research; timeliness of care, high quality of surgery and radiotherapy, and of pathological reporting. For head and neck cancers, the quality of care did not reach the optimal standards in most of the countries analyzed. A high proportion of patients was diagnosed at an advanced disease stage, showed delays in starting treatment (especially for radiotherapy), and there was only a very limited use of multi therapy. Conclusions: According to the achieved consensus, indicators of quality of care for head and neck cancers have to cover the patient journey (i.e., diagnosis and treatment). Our results, showed suboptimal quality of care across countries and call for solutions for ensuring good quality of care for head and neck cancer patients in all EU countries. One possible option might be to refer head and neck cancer patients to specialized centers or to networks including specialized centers
Osvežitev spomina na znamenite Slovence v Gradcu
No full textThe author of the article emphasizes the importance of refreshing the memory of famous Slovenes in Graz, e.g. Janez Nepomuk Primic, Gregor Krek and Karel Štrekelj.Avtor prispevka poudarja pomen osveževanja spomina na znamenite Slovence v Gradcu, npr. Janeza Nepomuka Primica, Gregorja Kreka in Karla Štreklja
Decreasing acidity in a series of aldose reductase inhibitors: 2-Fluoro-4-(1H-pyrrol-1-yl)phenol as a scaffold for improved membrane permeation
No full textTreatment of depression, anxiety and breast cancer in slovenian female patients
No full textIntroductionBeside psychological distress of breast cancer diagnosis and patophysiological characteristics of breast cancer it is also known that different treatments could have influence on mental well-being. The aim of this study was to investigate treatment of depression, anxiety and breast cancer in Slovenian female patients.ResultsIn the study were included 314 female patients with breast cancer treated at the Institute of Oncology Ljubljana between September 2004 and July 2005. Only 18 patients were not surgically treated. Majority (80%) of all patients were treated also with chemotherapy. In combination with chemotherapy 43% of all patients received also radiotherapy and 50% received also hormonal therapy. Altogether 72 (22,9%) patients expressed clinically important serious anxiety (Hospital Anxiety and Depression (HAD) score of 11 or more on anxiety subscale), 39 (12,4%) clinically significant serious depression (HAD score of 11 or more on depression subscale) and 51 (16,2%) clinically significant depression and anxiety combined (HAD score of 11 or more on both subscales). Among patients with clinically significant serious anxiety 19 (26,4%) patients were psychiatrically treated before inclusion into study. Among patients with clinically significant serious depression 13 (33,3%) patients were psychiatrically treated before inclusion into study and among patients with clinically significant serious anxiety and depression 24 (47,0%) patients were psychiatrically treated before inclusion into study.ConclusionsLess then half of patients with breast cancer with comorbid clinically significant expressed serious anxiety and/or depression has been psychiatrically treated before the inclusion in the study.</jats:sec
The association between induced and spontaneous abortion and risk of breast cancer in Slovenian women aged 25 to 54
No full textThe risk of breast cancer may be increased by induced or spontaneous abortion. The evidence for this association was evaluated in a population based case-control study in Slovenia, where 624 women aged 25-54 years with breast cancer diagnosed during 1988-1990 were matched for age and site of residence with controls randomly selected from the Slovenian Population Registry. Odds ratios (OR) and 95% confidence intervals (CI) were obtained by conditional logistic regression analyses. Spontaneous abortion was not associated with a significantly increased risk of breast cancer (nulliparous women: OR=1.41, 95% CI 0.22-9.01; uniparous women: OR=0.98, 95% CI 0.50-1.91; women with parity 2 or more: OR=1.40, 95% CI 0.91-2.15). Induced abortion was not associated with a statistically significant elevated risk. The risk of breast cancer was higher in nulliparous women (OR=2.49, 95% Cl 0.68-9.09), and was less among women who had more deliveries. In uniparous women, the risk of breast cancer appeared higher when the induced abortion took place before a first full-term pregnancy (OR=1.94, 95% CI 0.70-5.39) rather than after a first full-term pregnancy (OR=1.22, 95% CI 0.71-2.10) but neither of these odds ratios reached significance. We found no significant association between spontaneous abortion or induced abortion and breast cancer risk. This study found an elevated, but not statistically significant, risk associated with induced abortion among nulliparous women and among parous women when the induced abortion was before the first full-term pregnancy
P.2.a.020 Treatment of breast cancer patients with comorbid serious anxiety and depression
No full text123 P - Breast and colo-rectal cancer in Europe: problems related to collection and analysis of dietary data
No full text- …
