21 research outputs found
Colligères
No full textpar E. Mulsant et CL. ReyHandschriftliches Geschenkexlibris: "A M. Heer souvenir affectueux de..." Exemplar der ETH-BIBExlibrisstempel: "Entomologische Sammlung der eidgen. techn. Hochschule Zürich" Exemplar der ETH-BI
Dagny : tidning för svenska kvinnorörelsen / (Årg. 6, N:r 1/2)
No full textEsselde, En blick på Fredrika Bremer och hennes lifsgärning 5
Selma Lagerlöf, Mamsell Fredrika. En julhistoria 28
K. A. Melin, Nyåret 1866. Ett kvartsekelsminne. Poem 36
Charlotte Lindholm, Ur dikten "Veronica" 39
Ellen Fries, En moder till sin son. Bref från 1500-talet 43
Cecilia Wærn, Stockholm som storstad 52
Litteratur: L. N., Under tallar och pinier af Alfhild Agrell. - L. D-n., Dikt och verklighet af Helena Nyblom. - S. D., Från Medelhafvets skönaste ö af M. Anholm 58
Meddelanden från Fredrika-Bremer-Förbundet 62
Hvarjehanda i kvinnofrågan 6
Features of Business Models of International Events in The Field of Sports: The Example of The Formula 1 World Circuit Racing Championship
No full textВопросы устойчивости становятся краеугольными в условиях кризисов и внешних шоков. Цель исследования — представить особенности бизнес-моделей международных мероприятий в области профессионального спорта на примере чемпионата «Формула-1» для выявления возможностей устойчивости в условиях внешних шоков. Теоретическую основу исследования составил подход к анализу бизнес-модели А. Остервальда и И. Пинье, теория конкуренции М. Портера. Опираясь на данные анализа, а также предыдущие исследования в данной области, выделены общие черты международных спортивных мероприятий, присущие Формуле-1, определены основные особенности бизнес-модели чемпионата и выявлены направления дальнейшего развития. Данное исследование призвано восполнить недостаток работ по развитию и устойчивости бизнес-моделей спортивных событий с целью сохранения конкурентоспособности мега-ивентов в условиях внешних потрясений. Акцент в исследовании уникальных особенностей сделан на такие элементы, как взаимодействие с потребителем через киберспортивные дисциплины, продукция, ключевые партнеры и ключевые ресурсы. Результаты исследования могут быть использованы организаторами международных спортивных мероприятий при формировании конкурентной стратегии и стратегии развития.Sustainability issues become the cornerstone in the context of crises and external shocks. The purpose of the study is to present the features of business models of international events in the field of professional sports using the example of the Formula 1 championship to identify the possibilities of sustainability in the face of external shocks. The theoretical basis of the study was the approach to the analysis of the a business model. Osterwald and I. Pinier, M. Porter's theory of competition. Based on the analysis data, as well as previous research in this area, the common features of international sports events inherent in Formula 1 are highlighted, the main features of the championship business model are identified and directions for further development are identified. This study aims to fill in the lack of work on the development and sustainability of business models of sports events in order to maintain the competitiveness of mega-events in the face of external shocks. The emphasis in the study of unique features is placed on such elements as interaction with consumers through esports disciplines, products, key partners and key resources. The results of the study can be used by the organizers of international sports events in the formation of a competitive strategy and development strategy
The effect of functionalizing lipid nanocapsules with NFL-TBS.40-63 peptide on their uptake by glioblastoma cells.
No full textWe previously described a neurofilament derived cell-penetrating peptide, NFL-TBS.40-63, that specifically enters in glioblastoma cells where it disturbs the microtubule network both in vitro and in vivo. The aim of this study is to test whether this peptide can increase the targeted uptake by glioblastoma cells of lipid nanocapsules filled with Paclitaxel, and thus can increase their anti-proliferation in vitro and in vivo. Here, using the drop tensiometry we show that approximately 60 NFL-TBS.40-63 peptides can bind to one 50 nm lipid nanocapsule. When nanocapsules are filled with a far-red fluorochrome (DiD) and Paclitaxel, the presence of the NFL-TBS.40-63 peptide increases their uptake by glioblastoma cells in culture as evaluated by FACS analysis, and thus reduces their proliferation. Finally, when such nanocapsules were injected in mice bearing a glioma tumour, they are preferentially targeted to the tumour and reduce its progression. These results show that nanocapsules functionalized with the NFL-TBS.40-63 peptide represent a powerful drug-carrier system for glioma targeted treatment
Axonal regeneration is compromised in NFH-LacZ transgenic mice but not in NFH-GFP mice
No full textTo investigate neurofilament (NF) dynamics during the cytoskeleton reorganization in regenerating axons, and their electrophysiological and histological consequences, we used two transgenic lines of mice: neurofilament high (NFH)-LacZ and NFH-green fluorescent protein (GFP). In NFH-LacZ mice, NFs are retained in cell bodies and deficient in axons (Eyer and Peterson, 1994), while in NFH-GFP mice the fluorescent fusion protein is normally transported along axons (Letournel et al., 2006). Following a crush of the sciatic nerve, conduction recovery in NFH-GFP mice is similar to wild-type (wt) mice, but it is reduced in NFH-LacZ mice. Moreover, changes of axonal calibres following regeneration are similar between NFH-GFP and wt mice, but they are systematically reduced in NFH-LacZ mice. Finally, the axonal transport of NFH-GFP fusion protein and NFs is re-initiated after the crush as evidenced by the fluorescent and immunolabelling of axons distal from the crushed point, but NFs and the fusion protein are not transported along axons during regeneration in NFH-LacZ mice. Together, these results argue that the absence of axonal NFs in NFH-LacZ mice compromises the axonal regeneration, and that the NFH-GFP reporter fusion protein represents an efficient model to evaluate the NF dynamics during axonal regeneration
Insects trapped in the two plots.
No full text<p>Insects were trapped in the two periods (P1 and P2) with the net (bumblebees) or with the pan trap (wild bees and other hymenoptera) in <i>Montagne</i> (M) and <i>La Prade</i> (LP) plots. Data are the represented means of nine counts (3 days × 3 exclosures).</p><p>Insects trapped in the two plots.</p
Low-Dimensional Tools for Closed-Loop Flow-Control in High Reynolds Number Turbulent Flows
No full textMean GC-MS peak areas of the VOCs adsorbed on carboxen-PDMS-DVB SPME fibers exposed in the two grasslands.
No full text<p>Mean areas are indicated in percentage of the total area. Fibers were exposed in <i>Montagne</i> (M) and <i>La Prade</i> (LP) grasslands at the beginning (P1) and after (P2) cows grazing. Significance of the effects of the grassland (G), the period (P) and their interaction (G × P)</p><p>***p<0.001</p><p>**p<0.01</p><p>*p<0.05.</p><p>IQ: identification quality</p><p>a MS and RI in accordance with published databases and with the laboratory database</p><p>b: MS and LRI in accordance with published databases and c: MS in accordance with published databases, RI not available. Groups in the same row sharing the same superscript do not differ significantly according to Fisher Least Square Difference (LSD) analysis (<i>p</i> < 0.05).</p><p>Mean GC-MS peak areas of the VOCs adsorbed on carboxen-PDMS-DVB SPME fibers exposed in the two grasslands.</p
