4 research outputs found

    FAKTOR RISIKO KEJADIAN GAGAL GINJAL KRONIK DI RSUP. DR. M. DJAMIL PADANG TAHUN 2013

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    Tujuan Gagal ginjal kronik merupakan penyakit tidak menular yang perlu mendapatkan perhatian karena bersifat silent killer, dan menjadi penyebab kematian ke-delapan terbesar di dunia. Tujuan penelitian ini adalah untuk mengetahui faktor risiko yang paling berpengaruh terhadap kejadian gagal ginjal kronik (GGK) di RSUP Dr. M. Djamil Padang Tahun 2013. Metode Penelitian dilaksanakan pada bulan Mei hingga Juni 2015, menggunakan disain case-control dengan 138 responden. Pengambilan sampel dengan cara simple random sampling untuk kasus dan purposive sampling untuk kontrol. Pengumpulan data berdasarkan status rekam medis pasien Rawat Inap Penyakit Dalam RSUP Dr. M. Djamil Padang Tahun 2013. Hasil Hasil penelitian menunjukkan variabel yang berhubungan dengan kejadian GGK adalah hipertensi OR= 7,54(95% CI 2,85-19,92), diabetes mellitus OR=2,45 ( 95% CI 1,08-5,54), obesitas OR=0,34 (95% CI 0,13-0,86), dan hiperurisemia OR=14,45 (95% CI 4,37-47,79). Hasil analisis multivariat menunjukkan bahwa hiperurisemia paling berhubungan terhadap kejadian GGK. Hipertensi, diabetes mellitus dan obesitas merupakan variabel confounding terhadap hubungan hiperurisemia dengan GGK. Kesimpulan Berdasarkan hasil penelitian didapatkan bahwa hiperurisemia berisiko paling tinggi terhadap kejadian Gagal Ginjal Kronik (GGK) di RSUP Dr. M. Djamil Padang Tahun 2013. Sebaiknya instansi kesehatan melakukan upaya pencegahan dan mengontrol tekanan darah, kadar gula darah, dan kadar asam urat secara berkala terhadap pasien maupun masyarakat yang memiliki faktor risiko. Kata Kunci :hipertensi, hiperurisemia, diabetes mellitus, obesita

    Comparison of carboxymethyl cellulose (CMC) and microcrystalline cellulose (MCC) as filler for sago/citric based bioplastic by response surface methodology

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    Bioplastic material has emerged as one solution to the environmental problem caused by commercial plastic. Several raw materials have been used for bioplastic production, such as cassava, potato, and sago starch. This research focused on studying the effect of fillers and plasticizers variation to tensile strength and its morphology by using sago starch/citric acid-based bioplastic. The comparison of sorbitol and glycerol role as the plasticizer and microcrystalline cellulose and carboxymethyl cellulose as fillers were observed. This study was conducted by mixed and heated sago starch and fillers together. Then, citric acid and plasticizers were employed in the mixture solution. Next, the mixture was heated for 24 h then molded. The concentration of fillers, plasticizers, and citric acid were used as an independent variable which the interaction among them were investigated using response surface methodology (RSM) based on Central Composite Design (CCD). ASTM D822 evaluated tensile strength, and the morphological analysis was observed by using scanning electron microscopy (SEM). The results showed that the highest tensile strengths were 8.23 MPa for the glycerol and CMC process and 15.84 MPa for the sorbitol and MCC process. It was found that sorbitol and microcrystalline cellulose (MCC) increased the value of tensile strength twofold more than other fillers and plasticizers. As for the response surface method, the results describe the significant interaction between plasticizer and filler. It showed the tendency of increasing the concentration of fillers and citric acid decreased the tensile strength

    Comparison of Carboxymethyl Cellulose (CMC) and Microcrystalline Cellulose (MCC) as Filler for Sago/Citric Based Bioplastic by Response Surface Methodology

    No full text
    Bioplastic material has emerged as one solution to the environmental problem caused by commercial plastic. Several raw materials have been used for bioplastic production, such as cassava, potato, and sago starch.  This research focused on studying the effect of fillers and plasticizers variation to tensile strength and its morphology by using sago starch/citric acid-based bioplastic. The comparison of sorbitol and glycerol role as the plasticizer and microcrystalline cellulose and carboxymethyl cellulose as fillers were observed. This study was conducted by mixed and heated sago starch and fillers together. Then, citric acid and plasticizers were employed in the mixture solution. Next, the mixture was heated for 24 h then molded. The concentration of fillers, plasticizers, and citric acid were used as an independent variable which the interaction among them were investigated using response surface methodology (RSM) based on Central Composite Design (CCD). ASTM D822 evaluated tensile strength, and the morphological analysis was observed by using scanning electron microscopy (SEM). The results showed that the highest tensile strengths were 8.23 MPa for the glycerol and CMC process and 15.84 MPa for the sorbitol and MCC process. It was found that sorbitol and microcrystalline cellulose (MCC) increased the value of tensile strength twofold more than other fillers and plasticizers. As for the response surface method, the results describe the significant interaction between plasticizer and filler. It showed the tendency of increasing the concentration of fillers and citric acid decreased the tensile strength
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