3,926 research outputs found
Necrophilus sichuanensis Nikolaev 2003
No full textNecrophilus sichuanensis Nikolaev, 2003 (Figs. 1, 25, 26) Necrophilus sichuanensis Nikolaev, 2003: 149. Necrophilus chinensis Zhou, 2005 in (ZHOU et al., 2005: 63), syn. nov. Type material examined. Necrophilus sichuanensis: HOLOTYPE J, PARATYPE ♀: ‘ 12.08.2002 S Sichuan / N of Eryizuxian, NW / of Mianning, 4000 m / I. Belousov I. Kabak [leg., collector’s names in Cyrillic, p, red label] // Holotypus [or Paratypus] / Necrophilus / sichunensis / Nikolajev 2003 [p, red label] // ZOOLOGICAL / INSTITUTE RAS / ST.PETERSBURG [p, light brown label]’ (ZMAS). Necrophilus chinensis: PARATYPES: 1 J 5 ♀♀, ‘[text in Chinese characters, p] // PARATYPE / Necrophilus / chinensis / Det. Zhou, H-Z 2002 [p, red label with black frame] // Necrophilus / chinensis Zhou / [chinese characters] Zhou HZ [hw] // CHINA: Sichuan, N Jiulong county, / 3825m, streamside Salix scrub. / 11-14. vii. 2001 Pitfall trap J21 / Leg. Yu Xiaodong + Zhou Hongzhang [p] // Received iii.2005 from Zhou / direct pinned and without / paratype designation (see / Coleopt. Bulletrin [sic!] 59(10:62-69). / remounted + labelled by J. Cooter [p]’ (4 ♀♀ JCHC, 1 J 1 ♀ JRPC). Additional material examined. CHINA: SICHUAN PROVINCE : Kanding county and Jiulong county border, Mugang Ling mts, the central part, 29°13–24′ N 101°39–45′ E, 4100–4800 m, 23.-30.vi.2001, L. & R. Businský leg., 1 ♀ (JSPC); same data, 1 ♀ (JRPC); Jiulong-Zhou Shan mts, pass N of Jiulong [ca. 29°16′ N 101°31′ E], 4400–4500 m, 13.–21.vi.2004, R. Fabbri leg., 1 J (JSPC); same locality, 3900 m, 3.-5.vii.2007, Heinz leg., 1 ♀ (JRPC); NNE Eryizuxiang, SW slope, 28°47.7′ N 101°58.6′ E, 3818 m, v.2004, M. Häckel & R. Sehnal leg., 3 JJ 1 ♀ (JSPC); Sanya (= Eryizuxian), 28°47.7′ N 101°58.6′ E, 3800 m, 10.vi.2005, R. Sehnal & M. Trýzna leg., 2 JJ (JSPC); Jinping Shan mts, W Mofanggou, 28°13′ N 101°43′ E, ca. 3600 m, 28.v.–4.vi.2005, R. Sehnal & M. Trýzna leg., pitfall traps, mixed mountain forest, 6 JJ 6 ♀♀ (JRPC); same data, 23 JJ 20 ♀♀ (JSPC); same data, 32 spec. (MTDC); W Zhier (= Zi’er), 28°20.886′ N 101°28.361′ E, 4241 m, 5.vi.2006, R. Sehnal & M. Trýzna leg., pitfall traps, small fragment of mixed mountain forest with dominant Abies in small valley, 18 JJ 3 ♀♀ (JRPC); same data, 76 spec. (MTDC); same data, 15 JJ 9 ♀♀ (JCHC); same data, 7 JJ 5 ♀♀ (JSPC); mts. 10 km NW Dongzi, 28°34′ N 100°46′ E, 4500 m, 21.–24.vi.2006, J. Kaláb leg., alpine meadows, screes, 1 J 1 ♀ (JCHC), same data, 1 J 1 ♀ (JSPC). Taxonomic note. Necrophilus sichuanensis was described from two localities in the southern Sichuan province (N Eryizuxian, 4000–4300 m; NW Lajajia, 4200–4300 m) (NIKOLAEV 2003). Necrophilus chinensis was described from several places in the Sichuan province, Jiulong county, 29°17′ N 101°28′ E, 3735–4300 m (ZHOU et al. 2005). Both descriptions were written almost simultaneously: the paper of NIKOLAEV (2003) was published on 7 April 2003; the paper of ZHOU et al. (2005) was received by the editor on 15 August 2003 and published on 19 April 2005. Comparison of the holotype and one paratype of N. sichuanensis (from the environs of Eryizuxian) with a series of paratypes of N. chinensis showed no significant differences in external morphology. The only difference noted is a slightly different shape of the aedeagus, which is slightly more slender and elongated in the holotype of N. sichuanensis than in paratypes of N. chinensis and most of the additional specimens examined. In our opinion, this difference falls within an intraspecific variability. Consequently, N. chinensis is considered here as a junior subjective synonym of N. sichuanensis. Complementary description. Populations at different altitudes show continual and overlapping differences in TBL with TBL decreasing with altitude (samples from two populations with large series of specimens: Mofanggou, 3600 m: JJ 11.0– 11.5 mm, ♀♀ 11.5–12.0 mm; W of Zhier, 4241 m: JJ 9.5–10.5 mm, ♀♀ 10.5–11.5 mm). Female: sternum VIII weakly emarginate (or rarely truncate) posteriorly, spiculum ventrale short, stout, truncate anteriorly (Figs. 26). Ventro-medial sclerite of female genitalia unsclerotized medio-anteriorly and rounded, irregularly unsclerotized posteriorly (Fig. 25). Distribution. Endemic species, known only from China: Sichuan province (Fig. 27; NIKOLAEV 2003, ZHOU et al. 2005, this paper).Published as part of Růžička, Jan & Pütz, Andreas, 2009, New species and new records of Agyrtidae (Coleoptera) from China, India, Myanmar, Thailand and Vietnam, pp. 631-650 in Acta Entomologica Musei Nationalis Pragae 49 (2) on pages 636-639, DOI: 10.5281/zenodo.532190
A stable isotope investigation of fossil remains from archaeological excavations (methodological aspects)
No full textThanatophilus ferrugatus SOLSKY 1874
No full textThanatophilus ferrugatus SOLSKY, 1874 D i s t r i b u t i o n i n I r a n: Golestan, Guilan (SAKENIN et al. 2009), Khorasan (RUŽIČKA & SCHNEIDER 2002), Iran (no locality cited) (LÖBL & SMETANA 2004). G e n e r a l d i s t r i b u t i o n: Known from southern Russia, Kazakhstan, Kyrghyzstan, Tajikistan, Turkmenistan, Uzbekistan (SCHAWALLER 1982; NIKOLAEV & KOZMINYKH 2002; LÖBL & SMETANA 2004), Afghanistan (NIKOLAEV & KOZMINYKH 2002).Published as part of Ghahari, Hassan, Háva, Jiří, R, Aclypea, M, Dendroxena, L, Necrodes, F, Nicrophorus & L, Phosphuga, 2015, An annotated checklist of the Iranian carrion beetles (Coleoptera: Staphylinoidea: Silphidae), pp. 1501-1511 in Linzer biologische Beiträge 47 (2) on page 1507, DOI: 10.5281/zenodo.528250
Regulation of Constitutive GPR3 Signaling and Surface Localization by GRK2 and β-arrestin-2 Overexpression in HEK293 Cells.
No full textG protein-coupled receptor 3 (GPR3) is a constitutively active receptor that maintains high 3'-5'-cyclic adenosine monophosphate (cAMP) levels required for meiotic arrest in oocytes and CNS function. Ligand-activated G protein-coupled receptors (GPCRs) signal at the cell surface and are silenced by phosphorylation and β-arrestin recruitment upon endocytosis. Some GPCRs can also signal from endosomes following internalization. Little is known about the localization, signaling, and regulation of constitutively active GPCRs. We demonstrate herein that exogenously-expressed GPR3 localizes to the cell membrane and undergoes internalization in HEK293 cells. Inhibition of endocytosis increased cell surface-localized GPR3 and cAMP levels while overexpression of GPCR-Kinase 2 (GRK2) and β-arrestin-2 decreased cell surface-localized GPR3 and cAMP levels. GRK2 by itself is sufficient to decrease cAMP production but both GRK2 and β-arrestin-2 are required to decrease cell surface GPR3. GRK2 regulates GPR3 independently of its kinase activity since a kinase inactive GRK2-K220R mutant significantly decreased cAMP levels. However, GRK2-K220R and β-arrestin-2 do not diminish cell surface GPR3, suggesting that phosphorylation is required to induce GPR3 internalization. To understand which residues are targeted for desensitization, we mutated potential phosphorylation sites in the third intracellular loop and C-terminus and examined the effect on cAMP and receptor surface localization. Mutation of residues in the third intracellular loop dramatically increased cAMP levels whereas mutation of residues in the C-terminus produced cAMP levels comparable to GPR3 wild type. Interestingly, both mutations significantly reduced cell surface expression of GPR3. These results demonstrate that GPR3 signals at the plasma membrane and can be silenced by GRK2/β-arrestin overexpression. These results also strongly implicate the serine and/or threonine residues in the third intracellular loop in the regulation of GPR3 activity
In vivo imaging of colitis and colon cancer development in mice using high resolution chromoendoscopy
No full textBackground: Mouse models of colitis and cancer are indispensable for our understanding of the pathogenesis of these diseases. In the past, mice had to be sacrificed in order to analyse colitis activity and tumour development. We have developed a safe method for high resolution endoscopic monitoring of living mice. Methods: Mice developing colitis or colonic tumours were anaesthetised using avertine and repeatedly examined by endoscopy. A novel miniendoscope (1.9 mm outer diameter), denoted Coloview, was introduced via the anus and the colon was carefully insufflated with an air pump before analysis of the colonic mucosa. An extra working channel allowed the introduction of biopsy forceps or injection needles as well as surface staining with methylene blue in order to visualise the surface of the crypts and the pit pattern architecture. Results: Endoscopic pictures obtained were of high quality and allowed monitoring and grading of disease. Scoring of colitis activity as well as tumour size and growth was possible. In addition, pit pattern analysis using chromoendoscopy permitted discrimination between inflammatory and neoplastic changes. Biopsies yielded enough tissue for molecular and histopathological analyses. Conclusions: In summary, chromoendoscopy in mice allows monitoring of the development of colitis and colon cancer with high resolution. Manipulations such as local injection of reagents or taking biopsies can be performed easily
Thanatophilus porrectus
No full textThanatophilus porrectus (SEMENOV, 1891) M a t e r i a l e x a m i n e d: Khorasan province, Taybad, 786 m, 34°48′N 60°40′E, 13, 1♀, June 2010. New record for Iran. G e n e r a l d i s t r i b u t i o n: Widely distributed from Armenia to northern and western part of Central Asia (including Pamir mts and Karakorum mts), western China and Far East of Russia (SCHAWALLER 1982; RŮŽIČKA & SCHNEIDER 1996; NIKOLAEV & KOZMINYKH 2002), Afghanistan, Pakistan (RUŽIČKA & SCHNEIDER 2002; LÖBL & SMETANA 2004).Published as part of Ghahari, Hassan, Háva, Jiří, R, Aclypea, M, Dendroxena, L, Necrodes, F, Nicrophorus & L, Phosphuga, 2015, An annotated checklist of the Iranian carrion beetles (Coleoptera: Staphylinoidea: Silphidae), pp. 1501-1511 in Linzer biologische Beiträge 47 (2) on page 1507, DOI: 10.5281/zenodo.528250
Aclypea turkestanica
No full text<i>Aclypea turkestanica</i> (BALLION, 1871) <p>D i s t r i b u t i o n i n I r a n: Khorasan, Mazandaran (RUŽIČKA & SCHNEIDER 2002), North and northeastern Iran (MODARRES AWAL 1997), Iran (no locality cited) (LÖBL & SMETANA 2004).</p> <p>G e n e r a l d i s t r i b u t i o n: Widely distributed in Middle Asia, reaching as far as Kashmir and China (NIKOLAEV 1990; SCHAWALLER 1996; RŮŽIČKA et al. 2002), Afghanistan (NIKOLAEV & KOZMINYKH 2002), Pakistan (SCHAWALLER 1996), Kazakhstan, Kyrgyzstan, Tadzhikistan, Turkmenistan, Uzbekistan (LÖBL & SMETANA 2004).</p>Published as part of <i>Ghahari, Hassan, Háva, Jiří, R, Aclypea, M, Dendroxena, L, Necrodes, F, Nicrophorus & L, Phosphuga, 2015, An annotated checklist of the Iranian carrion beetles (Coleoptera: Staphylinoidea: Silphidae), pp. 1501-1511 in Linzer biologische Beiträge 47 (2)</i> on page 1505, DOI: <a href="http://zenodo.org/record/5282501">10.5281/zenodo.5282501</a>
Silpha tristis ILLIGER 1798
No full textSilpha tristis ILLIGER, 1798 D i s t r i b u t i o n i n I r a n: Guilan, Mazandaran (RUŽIČKA & SCHNEIDER 2002), Iran (no locality cited) (PORTEVIN 1906), Iran (no locality cited) (LÖBL & SMETANA 2004). G e n e r a l d i s t r i b u t i o n: European species, known also from western Caucasus and northeastern Turkey (ZAITZEV 1914; PORTEVIN 1926; HATCH 1928; HÁVA et al. 1998; NIKOLAEV & KOZMINYKH 2002; LÖBL & SMETANA 2004).Published as part of Ghahari, Hassan, Háva, Jiří, R, Aclypea, M, Dendroxena, L, Necrodes, F, Nicrophorus & L, Phosphuga, 2015, An annotated checklist of the Iranian carrion beetles (Coleoptera: Staphylinoidea: Silphidae), pp. 1501-1511 in Linzer biologische Beiträge 47 (2) on page 1507, DOI: 10.5281/zenodo.528250
IMAGING REGIONAL DIFFERENCES IN BETA-2 ADRENERGIC RECEPTOR FUNCTION AT THE CELLULAR LEVEL
No full textThanatophilus terminatus
No full textThanatophilus terminatus (HUMMEL, 1825) D i s t r i b u t i o n i n I r a n: East Azarbaijan, Khorasan, West Azarbaijan (RUŽIČKA & SCHNEIDER 2002), Iran (no locality cited) (SCHAWALLER 1982; LÖBL & SMETANA 2004). G e n e r a l d i s t r i b u t i o n: Known from southern Ukraine (Crimea), Romania, southern Russia and Turkey to Central Asia, reaching south-western Siberia and western China in the east (SCHAWALLER 1982; NIKOLAEV & KOZMINYKH 2002; LÖBL & SMETANA 2004).Published as part of Ghahari, Hassan, Háva, Jiří, R, Aclypea, M, Dendroxena, L, Necrodes, F, Nicrophorus & L, Phosphuga, 2015, An annotated checklist of the Iranian carrion beetles (Coleoptera: Staphylinoidea: Silphidae), pp. 1501-1511 in Linzer biologische Beiträge 47 (2) on page 1508, DOI: 10.5281/zenodo.528250
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