1,720,980 research outputs found
Autologous platelet concentrates for bisphosphonate-related osteonecrosis of the jaw treatment and prevention : a systematic review of the literature
No full textPurpose: Bisphosphonate related osteonecrosis of the jaw (BRONJ) is an adverse drug reaction consisting of progressive bone destruction in the maxillofacial region of patients under current or previous treatment with a bisphosphonate. Autologous platelet concentrates (APC) demonstrated to enhance bone and soft tissue healing in oral surgery procedures. The present systematic review aimed at evaluating if APC may improve treatment and prevention of BRONJ in patients under bisphosphonate therapy.
Methods: MEDLINE, Scopus and Cochrane databases were searched using terms like bisphosphonates, osteonecrosis, BRONJ, platelet concentrate, PRP, PRF, PRGF. No language, publication date and study design limitation was set. A hand search of the bibliographies of identified articles was also performed. The primary outcome was recurrence/onset of BRONJ after oral surgery procedures.
Results: Eighteen studies were included, reporting on 362 patients undergoing oral surgery in combination with APC. The adjunct of APC in BRONJ treatment significantly reduced osteonecrosis recurrence with respect to control. APC was associated with a lower BRONJ incidence after tooth extraction, though not significant. Heterogeneity was found regarding bisphosphonate type, clinical indication, treatment duration, triggering factors, study design, follow-up duration, type of APC, outcomes adopted to evaluate treatment success.
Conclusion: Though the results of this review must be cautiously interpreted, due to the low evidence level of the studies included, and the limited sample size, they are suggestive of possible benefits of APC when associated with surgical procedures for treatment or prevention of BRONJ. To confirm such indication, prospective comparative studies with a large sample size are urgently needed
Long-term (9-12 years) outcomes of titanium implants with an oxidized surface : a retrospective investigation on 209 implants
No full textTo retrospectively assess the long-term clinical and radiological results in a group of patients treated with Brånemark TiUnite implants supporting mostly single-tooth, and partial restorations.Material and Methods: The clinical records of 90 consecutive patients (mean age 55.9 years; range 21-82 years), treated with 209 Brånemark System MkIII or MkIV TiUnite® implants (72 maxillary/137 mandibular; 26 anterior inter-canine/183 posterior sites), were analyzed. Indication types were single tooth (n=21 implants), partial (n=180) and full arches (n=8). A delayed loading protocol was applied in 128 implants while 81 were immediately loaded. Cumulative survival rate and marginal bone remodeling were evaluated. Marginal bone level was evaluated by an independent radiologist from periapical radiographs taken at implant insertion and at long-term follow up. Plaque, probing pocket depth and peri-implant mucosa conditions were also assessed.Results: Mean follow up duration was 11.0 years (range 9.6-12.4 years): 181 implants (90.5%) reached at least ten years follow up, 100 implants eleven years, and 17 implants twelve years. Overall six implants failed in four patients (5 during the first year and 1 after two years) resulting in a 97.1% survival rate after 12 years. Mean bone levels at implant insertion and at the last follow up were -0.90±1.16 mm (mean±SD; n=169) and -1.49±0.95 mm (n=195), respectively. Mean marginal bone remodeling from implant insertion to the last follow up was -0.60±1.17 mm (n=168). At the last available follow up mean pocket depth was 1.65±0.84 mm. Peri-implant mucosa was normal for the majority (97%) of implants.Conclusion: This retrospective long-term study showed excellent survival rate of TiUnite® implants as well as favorable marginal bone response and soft tissue conditions
Behavior of aqueous-nanocrystalline-hydroxyapatite in oral bone regeneration
No full textABSTRACTPurpose: A skeletal segment consisting exclusively of bone is the target outcome of bone regeneration. Granular hydroxyapatitesform a hydroxyapatite-bone composite, unsuitable for effectively supporting implants, which may persist for manyyears. This work aimed to investigate the reasons for the bone replacement of Ostim®, a recently commercialized aqueousnanocrystalline hydroxyapatite.Methods: Histology, SEM and X-ray microanalysis were employed to analyze 6- to 9-month biopsies of post-extractive sitesor sinus floor lifts of the maxilla in 15 subjects.Results: The results highlight a great bone formation, Ostim® resorption with time by osteoclasts but also interstitial fluid propagationof Ostim® masses by percolation. A possible osteocyte protoplasmic involvement was also at work in concert to reach the target.Conclusions: The use of Ostim® as bone regenerating material leads to the formation of a highly suitable implant supportconsisting exclusively of bone in less than 12 months, i.e. in a remarkably short time
Armamenti, Conflitto, Decolonizzazione, Democrazia, Diritti Umani, Disarmo, Forze armate, Governo, Guerra, Guerra fredda, Ideologia, Imperialismo, Indipendenza, Internazionalismo, Nazionalismo, Nazione, Neocolonialismo, Organizzazioni Internazionali, Pace, Partito, Politica della sicurezza, Rivoluzione, Società civile, Stato, Sviluppo, Terrorismo, Terzo mondo, Umanitarismo
No full textBiomateriali come condizionanti la guarigione ossea nella profilassi strutturale
No full textCapitolo sulle caratteristiche dei biomateriali e sul loro utilizzo
Third-molar extraction with ultrasound bone surgery: a case-control study.
No full textThe aim of this case-control study was to evaluate the postoperative period and healing between 2 surgical methods (traditional and ultrasound bone surgery) that are used for mandibular third-molar extraction.Fifteen patients with impaction of both of the lower third molars and indications for their extractions were used in this study. Bilateral-mandibular third-molar extractions were performed at the same surgical time: traditional surgery with burrs was used on 1 side (control site), and ultrasound surgery was used on the other side (test [T] site). After surgery, the patients were examined at 7 and 14 days and at 1 and 3 months to evaluate tissue healing. The following was assessed at every follow-up: pain, trismus, swelling, and alveolar bone level.The study included 15 patients, and 30 mandibular third-molar extractions were performed. We found only 1 postoperative complication: 1 patient had alveolitis in the control site. Complete recoveries without any complications were reported in all of the patients at the T sites.Complete recoveries without any complication were reported in all patients at the T sites. The only disadvantage of the piezoelectric technique was the length of operation time, which was increased by approximately 8 minutes; however, this effect was offset by reducing the morbidity.Our preliminary study showed that Piezosurgery is an excellent tool for reducing the risk of complications and improving the postoperative period
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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