1,721,264 research outputs found
Current drug treatment of patients with bulimia nervosa and binge eating disorder: selective serotonin reuptake inhibitors versus mood stabilizers.
No full textOur aim was to review and compare findings from controlled trials and previous reviews concerning current drug treatment of patients suffering from Bulimia Nervosa (BN) and Binge Eating Disorder (BED). Thus we selected published articles quoted over the last ten years in the databases of Medline and Cochrane Library.
The combination of pharmacological and psychological treatments is superior to the single psychotherapeutic approach, which in turns is superior to the single drug treatment (just superior to placebo). Among drug treatments, SSRIs are the first line choice treatments, especially in primary care. They are more acceptable and tolerated by the patients, moreover effective even if investigations on long terms outcomes are lacking.
A number of patients, however, do not respond to these drugs. For them it is necessary to find new therapeutic strategies. Mood stabilizers are promising in this regard. In particular, topiramate seems to allow reduction of binge eating and weight in SSRI non-responder patients
Topological analysis of the electron density of the clinopyroxene structure by the maximum entropy method : an exploratory study
No full textIn the framework of a series of methodological studies to test the reliability of the reconstruction of the electron density distribution (EDD) by the maximum entropy method (MEM), we have attempted to check the possibilities of getting further information about the structural changes as a function of the chemical composition occurring in low-Ca clinopyroxenes by the analysis of the topology of the MEM EDD. The results of this study show that the topological analysis of MEM EDD yields results comparable to the bond critical points characteristics obtained in ground state EDD in minerals. Notable differences related to solid solutions have been found only at the M2 site of clinopyroxene structure. An attempt to describe the bond character at this site in the presence of significant solid solutions has shown differences related to chemical substitution that can be described in terms of variable ionicity. This result could be ultimately related to the different thermodynamic behaviour of the P21/c ↔ C2/c phase transitions shown by chemically different clinopyroxenes. Since MEM can deal with experimental data on solid solutions, which cannot be treated with other available methods to reconstruct the experimental electron density, this approach opens new possibilities for the study of changes in the EDD topology of minerals with complex chemical substitutions
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Study of the electron density in MgO, (Mg,Fe)O and Cu2O by Maximum Entropy Method and Multipole Refinements: comparison between methods
No full textThe electron densities determined by the maximum entropy method and by the multipole refinement approach are compared with each other, in terms of some topological properties according to the Bader formalism (Laplacian and eigenvalues of the Hessian matrix of the electron density at the critical points). The cases of MgO, (Mg,Fe)O and Cu2O are examined. The best agreement is observed for the critical points along the Mg-O, (Mg,Fe)-O and Cu-O directions, whereas larger discrepancies occur at the other critical points. Plots of the electron densities generated by the maximum entropy method and the multipole formalism along the most representative crystallographic directions contribute to elucidating the comparison between approaches
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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