8,289 research outputs found
Dixit Dominus a M. Bolzon
No full textTitre uniforme : Bolzon (17..-17..). Compositeur présumé. [Dixit Dominus. Voix (4), choeur à 4 voix, orchestre (Psaume 109). Fa majeur]Titre propre pris au départ. - La mention "a M. Bolzon" semblerait plutôt indiquer l'ancien possesseur. - Voix solistes : Sol 2 (2), Ut 4, Fa 4. - Choeur : Sol 2, Ut 3, Ut 4, Fa 4. - Vl 2, vla, vlc, cb, fl, ob 2, cl 2, fag 2, cor 2. - Ne figure pas dans le Catalogue thématique du grand motet françaisPrésentation musicale : [Partition]Incipit : Dixit Dominus Domino meo sede a dextris meisAppartient à l’ensemble documentaire : RISM1Appartient à l’ensemble documentaire : RISMMssPsaumes (musique
Rising to the SDGs: how can Nepal make meaningful progress by 2030?
Get PDFNepal has committed to achieving the UN Sustainable Development Goals but this will be no easy task. Ashutosh M Dixit outlines how collaborative approaches which acknowledge the interlinkages between the SDGs and good monitoring and evaluation will be essential to achieving meaningful outcomes within the next decade and a half
Dixit Dominus. Antonio Soler
No full textEl documento contiene el salmo a ocho voces y acompañamiento del compositor Antonio Soler titulado Dixit Dominus, que se conserva en la Biblioteca de Catalunya bajo la signatura M. 97. Se ofrece el texto en latín con su traducción al español y la partitura con la transcripción musical a notación moderna.N
Pseudoceros stellans Dixit & Bayyana & Manjebrayakath & Saravanane & Sudhakar 2019, sp. nov.
No full textPseudoceros stellans sp. nov. Dixit (Figs. 6, 7 & 8) Material examined: Holotype: One specimen (13 × 9 mm) as serial sections (16 Slides), remainder of animal in 70% ethanol. Collected on 21.5.2018, 15 m depth, Agatti Island (10°52′28′′N 72°11′11′′E), Lakshadweep, India (Regn. no. IO /IT/POY/00006) Type locality: Agatti Island, Lakshadweep, India. Etymology: From the Latin stellans (adjective) — starry or star studded; for stars like appearance on dorsum Diagnosis: Background body colour brown with numerous small white to yellow microdots on dorsum. Different sized yellow blotches present on dorsum but most of the small white blotches are present on marginal area. Half of the median area is marbled with irregular white shading, thus appearing as depigmented area. A thick black marginal band run around whole body including pseudotentacles. This marginal band is studded with microdots and small yellow blotches. Pseudotentacles are simple folding of the anterior margin, black and spotted with white dots on dorsal side. Cerebral eye cluster horseshoe shaped. Description: Live. Body small, oval and margin without ruffles. Background body colour brown (Fig. 6a). Numerous small white to yellow microdots present all over dorsum. White dots are numerous near median area and gradually turns yellow towards margins. Many yellow blotches of different sizes on dorsum near margins (Fig. 6a). Anterior half of median area is marbled with irregular white shading. Marginal band thick and black with minute yellow microdots and small yellow blotches. Pseudotentacles are simple foldings of the anterior margin, black and spotted with white dots on dorsal side. Cerebral eye cluster horseshoe shaped (Fig. 6b), tentacular eyes hard to recognize due to black colour of pseudotentacles. Ventral surface light brownish in colour. Preserved. Specimen brown in colour after fixation (Fig. 6c). Ventrally dull whitish in colour. Male and female pore are 0.6 mm apart, while female pore and sucker are 2 mm apart (Fig. 6d). Mouth and male pore are 1.2 mm apart while mouth and sucker are 3.9 mm apart. Pharynx ruffled with eight to nine folds and male pore is situated between last pair of pharyngeal folds. Cerebral eye cluster with about 60 - 65 eyes. Reproductive system: Male copulatory apparatus consists of seminal vesicle, free prostatic vesicle (Fig. 7a), penis papilla, penis stylet housed in male atrium which open outside via male pore. An oval seminal vesicle (317 x 157 µm) is present (Fig. 7b). Its rounded part oriented towards prostatic vesicle while tapered part is oriented towards cement glands. A free, small, circular and thick walled prostatic vesicle (80 x 58 µm) is present anterior to seminal vesicle (Fig. 7 a, b). Thickness of prostatic vesicle’s wall varies from 15 to 20 µm. Male atrium conical (283 µm x 187 µm) housing conical penis papilla (170 µm) with a stylet (Fig. 7c). Female copulatory apparatus consists of vagina, cement pouch surrounded by dense cement glands and female atrium. The vagina opens to a short female atrium via cement pouch which receives secretion from cement glands (Fig. 7c). Taxonomic remarks: Presence of ruffled pharynx, male copulatory apparatus just behind pharyngeal cavity, free prostatic vesicle, marginal tentacles formed by upfolding of anterior margin, centrally located sucker behind female pore (Faubel 1984) places Pseudoceros stellans sp. nov. in the family Pseudocerotidae while presence of characters such as smooth dorsal surface, single male copulatory apparatus with seminal vesicle (Fig. 4a) and armed penis papilla, pseudotentacles as simple folds of anterior margin, female pore equidistant from male pore and sucker (Faubel 1984; Newman and Cannon 1998) place this newly described species in the genus Pseudoceros. All of the above mentioned characters can be recognised in the present species from Agatti Island. The newly described species differs from all other congeners on the basis of dorsal colour and spots. Although there are some species under the genus Pseudoceros with spots (Pseudoceros astrorum Bulnes and Torres, 2014 Pseudoceros heroensis Newman and Cannon, 1994; P. josei Newman and Cannon, 1998; P. kylie Newman and Cannon, 1998; P. laingensis Newman and Cannon, 1998; P. leptostictus Bock, 1913, P. lindae Newman and Cannon, 1994; P. nigropunctatus Dixit, Raghunathan and Chandra, 2017 and P. vishnui Dixit, Raghunathan and Chandra, 2017) but the colour, size, arrangement, density and distribution of spots varies from species to species and is used for species identification. Pseudoceros josei, in terms of background colour and spots size and arrangement shows some affinity with the presently described species but it doesn’t have black marginal band. The spots turn white towards the margin (Newman and Cannon, 2005) which is opposite in case of P. stellans sp. nov. where spots turns yellow towards margin. Pseudoceros astrorum is also characterised by dark brown background with spots but it has a white marginal rim which is not present in P. stellans sp. nov. Pseudoceros kylie also possess dark brown background with cream microdots but has bright orange broken band just before the rim while the marginal band is black and continuous in P. stellans sp. nov. Other species such as P. laingensis (purple spots), P. leptostictus (small black and orange spots), P. lindae (golden yellow spots), P nigropunctatus (black spots with cream halo) and P. vishnui (purple to violet spots) possess spots with different types of colours, distribution and different type of marginal bands. Thus, in the light of above mentioned characters and comparisons, P. stellans sp. nov. is reported as a new species to science.Published as part of Dixit, Sudhanshu, Bayyana, Sharad, Manjebrayakath, Hashim, Saravanane, N. & Sudhakar, M., 2019, Polyclad fauna of Agatti Island, Lakshadweep, India: new records and description of two new species, pp. 246-260 in Zootaxa 4657 (2) on page 255, DOI: 10.11646/zootaxa.4657.2.2, http://zenodo.org/record/376911
Direct association between the Ret receptor tyrosine kinase and the Src homology 2-containing adapter protein Grb7
No full textAdapter proteins containing Src homology 2 (SH2) domains link transmembrane receptor protein-tyrosine kinases to downstream signal transducing molecules. A family of SH2 containing adapter proteins including Grb7 and Grb10 has been recently identified. We had previously shown that Grb10 associates with Ret via its SH2 domain in an activation-dependent manner (Pandey, A., Duan, H., Di Fiore, P.P., and Dixit, V.M. (1995) J. Biol, Chem. 270, 21461-21463). We now demonstrate that the related adapter molecule Grb7 also associates with Ret in vitro and in vivo, and that the binding of the SH2 domain of Grb7 to Ret is direct. This binding is dependent upon Ret autophosphorylation since Grb7 is incapable of binding a kinase-defective mutant of Ret. Thus two members of the Grb family, Grb7 and Grb10, likely relay signals emanating from Ret to other, as yet, unidentified targets within the cell
Pseudoceros stellans Dixit & Bayyana & Manjebrayakath & Saravanane & Sudhakar 2019, sp. nov.
No full textPseudoceros stellans sp. nov. Dixit (Figs. 6, 7 & 8) Material examined: Holotype: One specimen (13 × 9 mm) as serial sections (16 Slides), remainder of animal in 70% ethanol. Collected on 21.5.2018, 15 m depth, Agatti Island (10°52′28′′N 72°11′11′′E), Lakshadweep, India (Regn. no. IO /IT/POY/00006) Type locality: Agatti Island, Lakshadweep, India. Etymology: From the Latin stellans (adjective) — starry or star studded; for stars like appearance on dorsum Diagnosis: Background body colour brown with numerous small white to yellow microdots on dorsum. Different sized yellow blotches present on dorsum but most of the small white blotches are present on marginal area. Half of the median area is marbled with irregular white shading, thus appearing as depigmented area. A thick black marginal band run around whole body including pseudotentacles. This marginal band is studded with microdots and small yellow blotches. Pseudotentacles are simple folding of the anterior margin, black and spotted with white dots on dorsal side. Cerebral eye cluster horseshoe shaped. Description: Live. Body small, oval and margin without ruffles. Background body colour brown (Fig. 6a). Numerous small white to yellow microdots present all over dorsum. White dots are numerous near median area and gradually turns yellow towards margins. Many yellow blotches of different sizes on dorsum near margins (Fig. 6a). Anterior half of median area is marbled with irregular white shading. Marginal band thick and black with minute yellow microdots and small yellow blotches. Pseudotentacles are simple foldings of the anterior margin, black and spotted with white dots on dorsal side. Cerebral eye cluster horseshoe shaped (Fig. 6b), tentacular eyes hard to recognize due to black colour of pseudotentacles. Ventral surface light brownish in colour. Preserved. Specimen brown in colour after fixation (Fig. 6c). Ventrally dull whitish in colour. Male and female pore are 0.6 mm apart, while female pore and sucker are 2 mm apart (Fig. 6d). Mouth and male pore are 1.2 mm apart while mouth and sucker are 3.9 mm apart. Pharynx ruffled with eight to nine folds and male pore is situated between last pair of pharyngeal folds. Cerebral eye cluster with about 60 - 65 eyes. Reproductive system: Male copulatory apparatus consists of seminal vesicle, free prostatic vesicle (Fig. 7a), penis papilla, penis stylet housed in male atrium which open outside via male pore. An oval seminal vesicle (317 x 157 µm) is present (Fig. 7b). Its rounded part oriented towards prostatic vesicle while tapered part is oriented towards cement glands. A free, small, circular and thick walled prostatic vesicle (80 x 58 µm) is present anterior to seminal vesicle (Fig. 7 a, b). Thickness of prostatic vesicle’s wall varies from 15 to 20 µm. Male atrium conical (283 µm x 187 µm) housing conical penis papilla (170 µm) with a stylet (Fig. 7c). Female copulatory apparatus consists of vagina, cement pouch surrounded by dense cement glands and female atrium. The vagina opens to a short female atrium via cement pouch which receives secretion from cement glands (Fig. 7c). Taxonomic remarks: Presence of ruffled pharynx, male copulatory apparatus just behind pharyngeal cavity, free prostatic vesicle, marginal tentacles formed by upfolding of anterior margin, centrally located sucker behind female pore (Faubel 1984) places Pseudoceros stellans sp. nov. in the family Pseudocerotidae while presence of characters such as smooth dorsal surface, single male copulatory apparatus with seminal vesicle (Fig. 4a) and armed penis papilla, pseudotentacles as simple folds of anterior margin, female pore equidistant from male pore and sucker (Faubel 1984; Newman and Cannon 1998) place this newly described species in the genus Pseudoceros. All of the above mentioned characters can be recognised in the present species from Agatti Island. The newly described species differs from all other congeners on the basis of dorsal colour and spots. Although there are some species under the genus Pseudoceros with spots (Pseudoceros astrorum Bulnes and Torres, 2014 Pseudoceros heroensis Newman and Cannon, 1994; P. josei Newman and Cannon, 1998; P. kylie Newman and Cannon, 1998; P. laingensis Newman and Cannon, 1998; P. leptostictus Bock, 1913, P. lindae Newman and Cannon, 1994; P. nigropunctatus Dixit, Raghunathan and Chandra, 2017 and P. vishnui Dixit, Raghunathan and Chandra, 2017) but the colour, size, arrangement, density and distribution of spots varies from species to species and is used for species identification. Pseudoceros josei, in terms of background colour and spots size and arrangement shows some affinity with the presently described species but it doesn’t have black marginal band. The spots turn white towards the margin (Newman and Cannon, 2005) which is opposite in case of P. stellans sp. nov. where spots turns yellow towards margin. Pseudoceros astrorum is also characterised by dark brown background with spots but it has a white marginal rim which is not present in P. stellans sp. nov. Pseudoceros kylie also possess dark brown background with cream microdots but has bright orange broken band just before the rim while the marginal band is black and continuous in P. stellans sp. nov. Other species such as P. laingensis (purple spots), P. leptostictus (small black and orange spots), P. lindae (golden yellow spots), P nigropunctatus (black spots with cream halo) and P. vishnui (purple to violet spots) possess spots with different types of colours, distribution and different type of marginal bands. Thus, in the light of above mentioned characters and comparisons, P. stellans sp. nov. is reported as a new species to science.Published as part of Dixit, Sudhanshu, Bayyana, Sharad, Manjebrayakath, Hashim, Saravanane, N. & Sudhakar, M., 2019, Polyclad fauna of Agatti Island, Lakshadweep, India: new records and description of two new species, pp. 246-260 in Zootaxa 4657 (2) on page 255, DOI: 10.11646/zootaxa.4657.2.2, http://zenodo.org/record/376911
Polyclad fauna of Agatti Island, Lakshadweep, India: new records and description of two new species
No full textDixit, Sudhanshu, Bayyana, Sharad, Manjebrayakath, Hashim, Saravanane, N., Sudhakar, M. (2019): Polyclad fauna of Agatti Island, Lakshadweep, India: new records and description of two new species. Zootaxa 4657 (2): 246-260, DOI: 10.11646/zootaxa.4657.2.
Interaction of probiotic bacteria with commensal bacteria : an overview
No full textThe gastrointestinal tract of humans and animals is divided into sections that have different functions (Figure 3.1). The different regions of the gastrointestinal tract represent very different environments for the bacteria inhabiting the gut. These different regions are characterized by differences in pH, secretion of enzymes, moisture, temperature and presence or absence of villi on the intestinal surface. It is now known that different species of bacteria reside in different regions of the gut, and a species occupies a particular region in order to meet its nutritional and environmental requirements (Ewing and Cole, 1994). The bacterial flora of the GIT represents an ecosystem of high complexity, the understanding of which is very limited (Berg, 1996)
The Ret receptor protein tyrosine kinase associates with the SH2-containing adapter protein Grb10
No full textRet is a receptor protein tyrosine kinase that has been implicated in the development of the enteric nervous, endocrine, and renal systems. Mutations associated with multiple endocrine neoplasia types 2A and 2B (MEN 2A and 2B) have been shown to activate the intrinsic kinase and transforming ability of ret (Santoro, M., Carlomagno, F., Romano, A., Bottaro, D. P., Dathan, N. A., Grieco, M., Fusco, A., Vecchio, G., Matoskova, B., Kraus, M. H., and Paolo DiFiore, P. (1995) Science 267, 381-383). Using the cytoplasmic domain of Ret as bait in a yeast two-hybrid screen of a mouse embryonic library, it was discovered that the src homology 2 (SH2) domain containing protein Grb10 bound Ret. Grb10 belongs to an emerging family of SH2 containing adapter proteins, the prototypical member being Grb7. Using glutathione S-transferase fusion proteins, it was demonstrated that the SH2 domain of Grb10 specifically interacted with Ret. Additionally, using an EGFR/Ret chimera, it was shown that Grb10 bound Ret in an activation dependent manner in vivo. This is the first description of a receptor protein tyrosine kinase that utilizes Grb10 as a signaling intermediate
- …
