211 research outputs found
Global proteomics dataset of miR-126 overexpression in acute myeloid leukemia
No full textAbstractA deep proteomics analysis was conducted on a primary acute myeloid leukemia culture system to identify potential protein targets regulated by miR-126. Leukemia cells were transduced either with an empty control lentivirus or one containing the sequence for miR-126, and resulting cells were analyzed using ultra-high performance liquid chromatography (UHPLC) coupled with high resolution mass spectrometry. The mass spectrometry data have been deposited to the ProteomeXchange Consortium via the PRIDE partner repository with the dataset identifier PRIDE: PXD001994. The proteomics data and statistical analysis described in this article is associated with a research article, “miR-126 regulates distinct self-renewal outcomes in normal and malignant hematopoietic stem cells” (Lechman et al., 2016) [1], and serves as a resource for researchers working in the field of microRNAs and their regulation of protein levels
Catching-up and club convergence from cross-national perspective. A statistical study for the period 1980-2010.
No full textThe paper present the analysis outcomes on the catching-up process. Additionally it seeks for identifying the “convergence clubs” in cross-national section. It implements a traditional analysis of convergence tracking the catching-up process as well as the per capita income dynamics across time. The author finds no statistically significant relationship between average annual GDP PPP per capita growth rates (as exponential growth rate) and initial GDP PPP per capita (as natural logarithm) in a selected group of countries. The author also identifies the existence of “rich country cluster” and “poor country cluster” in the analyzed sample. The author applies for statistical analysis the country sample composed from 101 economies. All data concerning GDP PPP per capita are drawn from the IMF World Economic Outlook Database 2011. The time coverage is 1980-2010
Diagnostyka żelbetowej wieży antenowej o wysokości 60 m
No full textPrzedmiotem artykułu jest wieża antenowa o wysokości 60 m zaprojektowana w konstrukcji żelbetowej prefabrykowanej, składająca się z 5 segmentów rurowych wykonanych w technologii betonu wirowanego. Połączenia segmentów zaprojektowano w postaci specjalnych łączników, składających się z płyt stalowych skręcanych na śruby. W trakcie eksploatacji żelbetowy trzon wieży uległ
zarysowaniom i spękaniom o różnym charakterze, co stanowiło bezpośredni asumpt do zbadania przyczyn ich powstania oraz określenia sposobu naprawy. Celowi temu służyły przeprowadzone badania diagnostyczne oraz obliczenia statyczno-wytrzymałościowe konstrukcji wieży, z uwzględnieniem oddziaływania wiatru według Eurokodu 1 oraz nieliniowości fizycznej betonu i stali zbrojeniowej. Na podstawie otrzymanych wyników określono stan techniczny wieży oraz podano sposoby wyeliminowania występujących uszkodzeń i nieprawidłowości.The subject of this paper is a reinforced concrete (RC) antenna tower 60 m high consisted of 5 tubular segments made of spun
concrete. The connections between segments were designed in the form of special joints consisted of steel plates fixed by screws. The reason for undertaking this issue was the occurrence of cracks on the external surface of the tower shaft. For this purpose the relevant investigations and static analysis of the tower structure have been performed in accordance with Eurocode 1 and by taking into account the physical nonlinearity of concrete and reinforcing steel. Based on the obtained results the diagnosis of tower structure and recommendations for its repair and protection were made
Determination of stresses in RC eccentrically compressed members using optimization methods
No full textConcentration in ICTs sector – cross country analysis.
No full textIn the chapter below, the author presents inequalities in sector of new information and communication technologies. Having in mind inequalities we can also discuss concentration issues, and the concentration itself is a problem to which the author refers on first place. The paper is organized as following: first basic measures of concentration are defined, after we can read a discussion referring to concentration in ICTs sector when R&D expenditures are considered. Consequently the author analyzes basic concentration where use and application of ICTs goods and services are taken into account. To analyze the inequalities and concentration, traditional measures are applied, like: Gini coefficient, Hirschman-Herfindahl Index, and Concentration Ratio
Mobile Press-Register sleeve MP0075534
No full textGene Lechman Band performing / Grady and Betty Mathews fast dancing / Bettie Tanner and Buck Tillman dancing / Susie Buxton and M. C. Smith dancing / Mobile home / Bicycles and mobile home / Black ribbon on door of Mount Vernon seafood business / (Mount Vernon, Saraland
Catching-up and Club Convergence From Cross-National Perspective a Statistical Study for the Period 1980?201
No full textThe paper presents the analysis outcomes on the catching-up process. Additionally, it seeks to identify the ?convergence clubs? in cross-national section. It implements a traditional analysis of convergence, tracking the catching-up process as well as the per capita income dynamics across time. The author finds no statistically significant relationship between an average annual GDP PPP per capita growth rates (as exponential growth rate) and initial GDP PPP per capita (as natural logarithm) in a selected group of countries. The author also identifies the existence of ?rich country cluster? and ?poor country cluster? in the analyzed sample. For the statistical analysis the author applies the country sample composed of 101 economies. All data concerning GDP PPP per capita are drawn from the IMF World Economic Outlook Database 2011. The time coverage is 1980-2010
Okun`s and Barro`s Misery Index as an alternative poverty assessment tool. Recent estimations for European countries.
No full textThe paper discusses an alternative measure for poverty assessment - the Misery Index. An author develops an extended version of the index. The calculations are run for European countries, based on Eurostat datas
Resistance of Reinforced Concrete Columns Subjected to Axial Force and Bending
No full textAbstractThe paper presents a method for determining the resistance of cross-sections of reinforced concrete (RC) columns subjected to the axial force and bending. It takes account of the effect of concrete softening in plastic range and the mean compressive strength of concrete fcm. Such members are frequently encountered in engineering practice (pillars, bridges, viaducts). The stress-strain relationship for concrete in compression for short term uniaxial loading is assumed according to Eurocode 2 for nonlinear analysis. This stress-strain relation adequately represents the behaviour of the concrete by introducing four parameters. For reinforcing steel characterized by yield stress fyk, linear-elastic model with hardening in plastic range is applied. In the derivation of the resistance of the cross-sections of columns under consideration the following assumptions are introduced:•plane cross-sections remain plane•elasto-plastic stress/strain relationships for concrete and reinforcing steel are used•the tensile strength of concrete is ignored•the ultimate strains for concrete and reinforcing steel are determined a priori.The resistance of the RC cross-section is reached when either ultimate compressive strain in concrete or ultimate tensile strain in steel is reached anywhere in that section. The analytical formulae for the resistance NRm relating to the axial force and MRm relating to the bending moment are derived by integrating the equilibrium equations of the cross-section, taking account of physical and geometrical relationships as well as the condition of the ultimate limit state. On the basis of a combinatorial approach, twelve possible forms of the stress distribution in the section are considered. Using the derived formulae the interaction curves with the values of the normalized, cross-sectional forces nRm = NRm /(b t fcm) and mRm = MRm /(b t2 fcm) for the rectangular cross-section have been obtained (b, t – dimensions of the rectangle). The obtained formulae describe the cross-section under consideration in the phase of failure. Replacing the mean values fcm and fyk by the corresponding design values fcd and fyd one obtains formulae determining the design values of the normalized cross-sectional forces nR = NR /(b t fcd) and mR = NR /(b t2 fcd). For presentation of the proposed deformation model numerical calculations have been performed. They are presented in the form of interaction diagrams for rectangular cross-sections. Each curve refers to the corresponding value of the reinforcement ratio. The maximum compressive strain in concrete is calculated at the extreme fibre in the compression zone of the section. The points located on the nRm axis are related to pure compression, while on the mRm axis – to pure bending. The occurrence of the tensile strains in the cross-section leads to the crack formation in the concrete. Moreover, these solutions have been compared with those based on the parabolic-rectangular diagram for concrete under compression and with those obtained experimentally by other authors. In a similar way one may obtain interaction diagrams for ring cross-sections. Based on this analysis conclusions are drawn concerning application possibilities of the proposed approach
Digital divide – inequalities in level of implementation of new information and telecommunication technologies. Cross country study.
No full textIn the paper presented, the author considers few aspects of the so-called “digital divide”. It is easily noticeable worldwide, that new information and communication technologies (ICTs) “possess” a great ability to spread, at high pace, among countries from all around the world. At the same time, we can see that ICTs are being implemented at different pace in difference economies. Different pace of ICTs implementation generates significant inequalities in level of usage and application of these technologies in different countries.
The main purpose of the paper is to assess magnitude of existing digital divides among countries, which can partly explain existing inequalities in use and application of ICTs.
The author will apply relevant methodology – taken from basic taxonomy methodology – to measure the digital divides among economies.
All countries where necessary data is available and reliable will be included in the study
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