6 research outputs found
In silico determination, peptide engineering demonstration, and preliminary docking studies of potential antimicrobial peptides from cocosin-1 againts methcillin-resistant Staphylococcus aureus Muramyl E (MurE) Ligase
No full textThe alarming rise of antibiotic resistance triggered the search for antimicrobial alternatives such as plant-based antimicrobial peptides (AMPs) as they possess a wide range of bioactivities. The main objective of the study is to determine the in silico antimicrobial probability of peptides from enzyme-digested cocosin-1, improve the antimicrobial probability of selected peptides through engineering, and perform docking experiments analyze possible peptide-enzyme interactions. Cocosin-1 was separately digested using pepsin, trypsin, and chymotrypsin. The top three peptides with the highest antimicrobial probabilities produced per enzyme were subjected to site- specific amino acid (histidine) substitution while maintaining the conserved amino acids intact.
Then, the top five engineered peptides with the highest antimicrobial probabilities and probability improvements were selected and their physicochemical properties were assessed. Finally, the original and engineered AMPs with the highest antimicrobial probabilities were modelled using PEP-FOLD3 and docked to Staphylococcus aureus muramyl E (MurE) ligase, our sample bacterial enzyme, using ClusPro 2.0 to assess any significant binding interactions using using Pymol v2.1.0 and VMD (visual molecular dynamics) v1.9.3. In silico enzymatic digestion and AMP prediction yielded 9 AMPs (CAMPR3) and 25 AMPs (DeepAmPEP30). Upon performing location-specific triple amino acid substitution, the peptide 129QRSEREEGERHRW141 possessed the highest antimicrobial probability (82.45%) while 33QSPRRSVSSRNECRIERL50 exhibited the highest antimicrobial probability improvement (31.70%). Findings from the in silico peptide-MurE docking studies show salt bridge and hydrogen bonding interactions are present which could be essential during AMP-based enzyme inhibition. Results showed that site-specific changes in the amino acid composition may affect the antimicrobial probability of selected peptides
Topoclimatic conditions in summer seasons in the Kaffioyra region (NW Spitsbergen) in the years 2005-2009
No full textW artykule przedstawiono zróżnicowanie temperatury i wilgotności względnej powietrza oraz kierunku i prędkości wiatru w rejonie Kaffioyry (NW Spitsbergen) w sezonach letnich 2005-2009. Na podstawie pomiarów w 8 punktach stwierdzono znaczne różnice topoklimatyczne uwarunkowane rodzajem podłoża, wyso-kością nad poziom morza, odległością od morza, ekspozycją oraz lokalną cyrkulacją atmosferyczną. W rejonie Kaffioyry często występują sytuacje inwersyjne, związane nie tylko ze stratyfikacją termiczno-wilgotnościową napływających mas powietrza, ale również oddziaływaniem czynników lokalnych. Zróżnicowanie topoklima-tyczne zmienia się w zależności od stopnia zachmurzenia i pory doby oraz w czasie formowania się wiatrów lokalnych (wiatry lodowcowe i fenowe).The paper presents the spatial differentiation of the meteorological conditions in the summer seasons in the Kaffiřyra in the period 2005-2009. The meteorological measurement points (4 automatic weather stations and 4 electronic devices measuring temperature and humidity, 2 m a.g.l.) were located on the Kaffiřyra Plain (KH) on the Waldemar Glacier area (ATA, LW1, LW2) and on the mountains: Kuven (KU), Grĺfjellet (GF) and Prins Heinrichfjella (PH1, PH2). The analysed five seasons had changeable weather conditions dependent on types of synoptic situations. The highest air temperatures were recorded on the coast (KH 5.8°C) and on the marginal zone of the Waldemar Glacier (ATA 5.1°C). On the glaciated area air temperature is decreasing with the altitude (LW2 2.9°C). The largest temperature lapse-rate is recorded at the transitional area between the glacier and its marginal zone. Growing altitude lowers air temperature on the mountain ridges (GF 4.0°C, PH2 3.6°C), but temperature inversions are recorded quite frequently in the region. Relative air humidity is high due to low temperature and large frequency of occurrence of maritime air masses. The highest mean relative air humidity was recorded on the coast (KH 88%) and on the firn field of the Waldemar Glacier (LW2 84%) as well as on the mountain ridges (PH2 92%). The course of the relative humidity is significantly influenced by foehn winds. Wind directions and velocity in the study area are strongly dependent on the synoptic situation and influence of local factors, mainly orography (foehn winds). Wind regime in the Waldemar Glacier significantly differs from that observed in the Kaffiřyra (here the tunnel effect is observed as a consequence of the narrow Forlandsundet, presences to the abovementioned plain), mainly due to katabatic winds occurrence
Measurement of Spin Observables in the ~p ~d Breakup Reaction
No full textWe update our Letter-of-Intent 202 for Measurement of Spin Observables in the
~p ~d Breakup Reaction. An estimate of the overall beam time needed for completing
the measurements is specied and a timeline in view of the planned PAX experiments
is presented.
The proposal aims at a study of the three nucleon continuum in proton deuteron
breakup reactions, between 30 and 50 MeV proton beam energies, an energy range
where there have been few and limited measurements. The large coverage of the PAX
detection setup and the energy range chosen will provide essential new data intended
as a laboratory for chiral eective eld theory, the modern theory for nuclear forces
relevant at low and intermediate energies.
Vector and tensor analyzing powers and spin correlation coecients will be measured
and evaluated over large kinematical areas in the ve parameter phase space of
the nal state containing three nucleons. For the analysis the sampling method will
be used, a technique developed specically for the complex analysis of three particle
nal states, providing a direct comparison between experiment and theory
ViewScan_0000
No full textSite jailij falo g,Ito\
STAN'FORD UNIVERSITY. CAI... MONDAY. SKIT. 15, I'.arj.
8ESI0B OFFICER* CHOSEM
SUNDAY 8EBVICES BEOUN.
OBADUATE3 WILL TEACH
SCHEDULE It COMPLETED.
Claaa of 1SOS aTornioal** and Xlacla Dr. Murray D*li***-eThought'ul Ad- Msmbsrs ot 1B03 Who Have 8a- Busy Immd Abaad for Vartitjr and
a Ticket M TL.i dmaa in th* UoJTsrsily cured Poaition* for th* Frsahtu*--. Class Oame*
••uneler. Chsp*l. Tear. Arr*r,h--1
At« Meeting ol Ibe Senior Class| Thot-e who attended Ihe chapel Following!* a li*t of Stanford Tbe completed acbedule ol fool-
held in the ch.'-c! thi* afternoon (service yesterday morning had the gradual** "f 1902 who have seemed liall game* for llii* season i* unii*-
ofljeata for thiseetnaster were nom-; privilege of heating lira. A. IV. •iluation* MM teacher* tor Ihe com- ually full. It**idea Varsity ptiin
it.*led, and a* there wa* hut one Smith, after an abetnee of mora ing year. Thi* list aa* obtained with Nevsd*. ttcliat.ee, Athletic
noii.itirr for each |K«itinn the sre- tbsu tilieeii month- tr.ni. the Uni- al the office of ibe Education de- Club, and the Alumni team, I bete
retary was instructed to cs-l * solid vrrsity, sing **0 Ya That Lore llie partmenl, and i* hy iiome.n* com- area large number of Freshman
..allot for the ticket. Those iinmi- Lord,' Iran the ..talon" "lite plelr. I.ul contains only the name* matches in eight, L'titil the Interna led end elected ate a* follows: Lord is King," by Itarntey. Dor* ol those of whom knowledge ha* collegiate Freshman game mi th*
Pieeidei.t. It»y O. liadley. tiomi- in** lha ,..-t -roar Mt*, Sin till ha- cine lo the depnilmeiil. ISifa of Uct otter the young*ler* will
naled by P, 0. Harper; vic**-pre*i- hern smgii >■: ratArio* tn New Fern Aldailt, public eebool* of l-e kept raliriuely busy with prac-
dent, It. E. Warfield, tioii.inaied by York. Ariaona; Irmagarde Itichsnl*. puh- lice games. Their season is to If
C K. Siudley, secretary. Mis* The serin.n» veeierdsv, given in lie school- of Kern counlj. A. J. inaugurate*! al Itiirliugamr, where
Tbarsaa May Wilbur, hy A. P. thoughtful, aarncei, and direct C-pj.. Harvard Hoy*' School, Loa tbey play St. Mattben'e nest Sal-
Ilarri*; treasurer, H C UcComlafa, manner, a** by In A I Murray, Angeles; Annie llairell, I'alo Alto urdsy, and (mm that dale ihey
l.v K. E Kengle; aarasjanl-at-arma, wbos]tolieol worship and prayer, public school; Anna M. Laird, I- - will play nearly in., name* a arek
I,. C. Henley, by It. C. McCtm-l. and one'- altitude tt.aard God He Angeles public aehoole; Anna It. until llie day ol their big snuggle
Thia utianiitii.il* lelectlon does said that worship abould be waiting Aebenlelter, New Mciicn; Florence A moat liiUtaallng fealuie of Ilia
.way with tht-necessity of another Upon lbs Lord, or il i- in vain Hevao tl. Thobuiu School, I'alolteaaon la the revival ol claa. games.
mMting ol the cists, There air •■,-.•,..- who have iiosen-r Alto, K. II ll.rrn. Harvard BojT.* Tba Frcshii.cn meet the 8opho.
■toy (>. Hsdley, tbe new pre*i- ol God's nearness, and those wb.. School, t,»- Angelas; alary i re- on the .tOth of September,
dent.' irgisiers from Whatcom, find ihe thought ol tJods preMuci l<ockay, Haiti's School, Klltaheth and ihe Senior* play tbe Junioi*
Washington. He had Iteen assist- one ol di-i.iiri.iiic Such men ran Bai lay. Halloas high school; C M the 7lh ol Oatobar. The deciding
anl editor, associate editor, man- not worship and pray and he) thai lUtler, rHocklon high school; Ethel I Contest will U held on the |3tll.
■glng editor, and editor-in-chiei Qod bears, ll.r oransHa f lha McCJallan/ Sun ftauelacu public I he t plua schedule ol Varsity
re*|iectively of liir |iaii.vI'ai.o AlTo, view rinding the idea ol (loir- schools, France* Short, .-an Mateo and Fie*hinrn la glean la-low.
holding the Utter |-oa]Uon ir.e,c. presence one from which we would Uon'SobooI; Julius 11 Cohn, Itiv- s*pt. 20, Freshmen v». St. Mai*
ond aamaatar ol bis junior year llel flee, i* that of the higher sepira- eistde high school; .1 .,,..■■- Com.. Uw*1*, at lltuliugame.
laamemberol UieBuphronis I.il-jth f llie Jewish religion. Modesto high kIiooI; Lucy A Bapl, 24, Kraahu.en vs. I'alo Alto
erary Society and ol the Kappa Kewrerelatitmaare needed today Corker, Mendocino high school; II|gb School, cainpua.
Sigma fraternity. Hi* major Study that God i- not nn abstraction, that Helen Ftcke*. Santa Crur, enmity Sej.t. 37, Fm<*Iiiiipii v*. IUhiii.nl,
i* English, [walking with Hod i* nut a mere publii school*, Charlotte M. I.«ru, campii* (mniiiiiig).
Dshaian Kun-t oflenra echo from Old Trslauiet.l tbiiiking. ] a**i*l«nl Hi-lory de|.*rtii.eut.Si«n. ■ Hept. 27, Vanity vs. lUlia.nr,
Naeinri. and 1 bib lexiati liter-, .„ to ^k for c,>n,f„rtahIt. ^g,.; high echool; Henry W, Slsger, Sel- Se',,1. 80, Freshmen vs. BopllO-
ary Nwieiiea mat lor ihe firM """JJoy and peace; ilia lodo tbe right, ma U high ichwl■ Angui I. ■ mure*, cam .«..
which, however, secures joy stidiCsvaiiagh, .Marysvflle high sch'-ol. (>c|. 8, Freshmen v*. Ilerkeley
eace, "Tbey that wait ujKin the, Sherman Kimball, Napa high High School, campu*.
«rd "ball renew their strenj,ih." ;-.-h....!; Favette Itirlch, ltaker*llehl Ucl. •]. Alumni v*. Varsity, cam-
In the crUe* thai erne into .me'- litKh mIidoI; I'eU'iit Uonlgomtrr
this seineater Saturday night and
named tbe following officers:
I'hihdesian. I'residetil, C. K '
Siudley, '03; vire-ptesjtieiit, C. II.
.lary, K. K
ler. 'Of; treasurer, M. A. Thomas, L-jriuii God Ths
'tM.sergeant-al-anu*, W W.Cnpp, om> lo do Oia duly
TO; rep resell tat ive- 111 the Inter- r., tti |^Br ,h(t „,
let'y I'ehating l^agu*. I.. K onon „. *,,, rr-i*t
of
:th to
idlev Imi
ngl
It It
Harter. *0I, I' Mariii
Knight. "03.
Naatorla. -President, R. W. Kv
eretl, Ul; vice-presideul, C. II.
Ilattori, TOj srcret.iry-treB.il rer,
I'rinl Swing. '11.1, sergeaiil-at-srin*,
J. II. I'sge, 03; representative, in
the Inlersociely Hchating LeagtM,
K. \V. Kice, 02. E. O. lti*le, TO,
A. Ci. Thompon, '03.
Ipscial Bats to San Jo**.
A apecial rale ol 70 cent* for thi
round trip to San Jnee will lie mad*
by :h* Southern Pacific Company
Tuesday.Seplt-u.Ur h'.lli.IOacOD0»
tn-Utr Iboee who w.-l. to see Buffalo Hill'* Wild We-t Show, Tick
el* will I e 1-... ,1 returning on the
1,1.- \|,
e.r- Hhool; I. I
that raauIschool; Fh
enptaUori Paul publk
Mo
tcliool; Sa
mi.in Vlaa
Spink.,
P.
high.
.0 hi
hi '.Junior* v*. Senior*, campu*.
1.1. 'J, Saula Clara v*. Freehliieu,
II, Varsity v*. Italian
diflicultie*.
to lin.l gri
pre.d.er
1-: 1'iirkei
ihoole; and Minn
Tlio*e who have alaber, Ball Francisco public u.'t. 1», Final Cla-* game.
re with li.-d have school-. , (i,t 111, Alumni v», Varslly,cam
■an mere help over Dorolliy ChsiS U with Ibe pub pui
bay have l raaonder liahlog Brm nl Gtnn & I'o.Sanl Oct. Iff, InUic.lUgiale Fieahman
tienc*.. whfchialbe Pre John J. MeManla holds *nmr. San Franoleeo.
■aVer. Prayer la not a Chic.-i,*.. fun er-ity fellowship. Oct, Sft, Vawily v*. Itellance,
ill ..I il.ei.-ird. hiit, campus,
ido Hi* will The Dr. JordeD Will Bp.ak. Sux I, Nevada v*. Varsity, cam-
icbce in vain if he President Jordan will deliver hi* una,
it easier lor men lo n lal lecture to fre-lin.en minor Nov. H, Intercollegiate Varsity
•ee with a *piritual eye. There ate ion ' Tuesday) evening in the A* game, San Francisco.
some wh« worship be-t In their ..an .etnl.lyfl.il Hi* aobjett la to ba ,
closet*, ton.e who worship be»t in "the Making of Stanford Men." BubeUta tine; root ball.
Iheir daily toil, following Ihe pall, st.d the lecture Is one of InUreall Tb<-*« .ludet.U who are -ul-li-
of duty. But tharebt acommunion not only t nasi atiidaota but to tuiing f.e,.tb*ll tor gymnasium work
in worship, an action and reaction lie elodenl body in genera) [„„ i^„ di.,,,,,^1 f,(,m »,„■, in-
,e another, a siimiilali.t.. __ '^,\^ Ttt„ Brei j. j, ||lllir„ut |,
auto- (o. th* L*be.ry. iil%]„ A ,j Chaaj^ W ||. Cltand*
e day in *«vet.. Fifteen marble Malue. arrived at it,,t y ,* Cbri.lv, I.. I.. Clarke, K.
irally from ih* Kolptor Cothran. w. Il.'|fc.u, A <i DudUy,
n privilege, boa A Fnlli ..f rlorence, and are being y A FUnder*. It l>. FristwIU.
ever, io draw i-tether once a week set upon lha |>edc*lal* of ibe I.i- )■. \\ Fruiell. A. A. Ilarwirk, J. II.
Albsruo* 8**ks tfi-istsismsal lo hear words ol prayer and lo sing hraryg.lleiyrjiliiigt.sday KUven J|„(,ki,l(i H. R Howard, 0. 0
Professor tlaorga C Edwards, .walaaa, to wail with other* upon a are while marfaea boeU about 1 wo Jacobs, k. V, Kehrl.in.J C. I.unl,
chaJmau of ibe Facnlty Athletic ■""" ; «' '«■• hightot- aHoalba -malUr \\- p Ummmm, A. A Mathewann, It.
Committee of the University of Cal — nadartale, and ia., ate life-aita Maihen*. I„ J. Mayiei., J A. M*r
iforuU still refuars u> change his racaity Field ciab Mees*. Hatuaaol Ibe tame itrtne to go on rllLO. H. Ifoora, 0. K HuniaMjr,
l-«iii.m regarding the rein.tate. The annual -p-Hy-up" nl the- >he two Urge p*de-l*l> in tbecenler \t JJ. Vorter, W. It. SchoSeld. J. J.
mrtit of Captain AIUri«.n All-it- Facullv Field (lul. n«, held at ihe -f lb* fr.mt and back railing. One sbeehy, ll. T. .-bine. A. It. Tooth*
•on however, h.. c.o.e out l-t elubbousc on Friday nigbl "f- hurt baa wot yet arrived. IdKar.C. H.Tucker, I. J. Webb, P.
practice.and. with Manager Her.. 1... Urer* were elected for the ensuing "•••* -***• ••*+*** Malue* repre- tVbllealda, F M. Wilbur, I). It.
haaapi*alrd I- Tr.-idei.t Wbeeler .ear a. followa: President. In—'"l l-em-lbene* atgl |..., mm., Wilaon.
WbelherP.e.identMteelrr-d.ee Fran* A ngell; secretary, l»i Una -hi,!. !-the llah.n name for Poly- ■■ ~—^
fll to reverse lbs dedaiou -f Pm* F.rr.t.d. traasurar. Profeswor C It bymuU, the rauaa ol tba loblime Mu» Ar* iuil B^vtrt-,...
fea-.r Kdwards i* the question •■! Wing. hvtiin atnl id the faeullie-nf Ieirn- Twenty new sin.lent* r*gi*l*rc<!
prom inane* just t...a acnes ihe bay
-lly hi
et-ecial tram leaving ihe Narrow 1, -,
i;uaged.(-.t.t 11 30p.ii. ...id .... ■T"w m
■ II regular tran - tl,* |7lb
-C. D. H'olrott. director of ihe P«
ITnlled Suiaa Geohifh Purray, waa -»
g and rcmeinUrini.. Ibe bust, lodajf, whiih bring* tba l"tal up 10
f.. ni School defeated ibe ar- -.1 lEapbael, Canora, Oatllao, 130", a* *g*in*t 1 NT on the same
yiecbnic High School team of Sewlnn, loonai Edlaoo, fjasienl date last year. The pii-*enl enroll*
1 |-i,t.(iM-.. >ai<.r.l.v at llel i.tani. ft.-iniel Wrl-ier, Ciceto. met.t eirerds that of the entile
nl hj tbe -i- re ol !'.• Sh*k*|-ere, Pope, and Longfellow, year preceding
3
No full text¥
FA_LO alto times.
PALO ALTO. CAL.
THURSDAY. DEC., 5. 1895*
Local Diie.a.
The Ladle* of the M. E. Cliurcb will
hold their baxaar on the ellrruoone an.1
evenlnge of I'riday and Bat unlay of next
week In Nortre* Hall.
Tha Sopenriaoie ol lbe county appointed B. ». SpauWiag poo_-lu_aaier
oi MaytUld township.
A blej-cle, betoaging lo a atodent ot
Want-mil* Hall preparatory school, aaa
rtuleu Irom in front of llanaon'a lumber
yard on Monday.
Aconr-t-t for tlie I .n.-iii ol the I'alo
Alto M. K. Cburcli elll I bi given in San
.'rauciaca. Priilav livening, Deoriiilier
20, at UieOentral Melliodlal i .i_r.li.
Tba regolar monthly buslnesa i„„. lin>:
nml a,n-iai ol the i.f>_„nii U-aguc will
be bet.! at the rraidenc* ol Bev. M. li.
Alexander. Friday waning, December fl.
Tbe signs moat go. so It would appear
from tbe aay iu which theae on poke
have disappeared daring the peel few
daya. Evidently Ibo new ordinance is
gsang Into effect.
Tbe annex of A. S. Ferguson's dry
ooods store has been |>laa_-re.l and will
Txt ready for occupancy In a short lime.
Mr. fl. W. Moalier liae cotuuienced work
on the store rUlnr**.
All Unitarians and all other* inler-
eeli-d Id lhat uhaau nf rellgiutia Ihnugbt
are invited to ni-ei al Mi. Klrlcher'a,
I'ajtillep Halt. . antlay ereninit, Drona*
ber 8th, halt paat seven o'clock.
Mr. Walt Heche*, a mieiay man,
wbo bat lately mored la Palo Alto. Is
(si.j.arinj a cahinel ol gold and ailrrr
ore _l,i,li Ire will loan lo tit* Unirer-
sity Mu--oin toll* lie put on exhibition.
Dunns the-jiaet week anulhrr robberv
occurred at Redwood City. Tlie work
waa nl n .-liitnav character and wat no
doubt accomplished by Irani)*, A few
daya afterwartls the man were caught in
MonnUin View.
Tha following is the mil of honor lor
ihoee neither absent nor tardy in the
primary department nf tlte pablk
a.1,,.1- Arthur Shernisn, Jnlin Caalicl,
Harry Wai.-. Tommy ami Hair. How-
man, l„ !■„■ Madigan, Ir. .n,- Witliaras,
llertran.1 Wells. Alice Taylor. Myrtle
Lewln, I-il; Hicltrna.
We are promised a treat In the in.r
future hy Mia* Little, ssslslr.1 bv Mist
(..Ichor, Mrs. Hiil,-liina.,n am) Ilr.
l.ittlB. who will tiler a sunn recital. It t.
understood thai tlio program wlll Im
tha in,,i- Interesting herauao la-galy
a,-i.-.-t.*. 1 from such bright, nualem.
American composer* es L> Kuven
Klbelbert. Serin awl Nsltllinger.
THE WATER WHB
Huv of Uii I'nsittit Citizens Till
011 Ihe Water Questiw.
TBE CiiSSESSIS OP OH POINTS THA
IIBIIIK MB.I TOWS WATER HIST
We bare been able lo gather together
the oplaionaof many oC the ouirne ol
tbe town u|.,n itae t)ueatioti of water
aorka. From tack ol Opportunity and
apace io the peper we hare not been
.hie lu approach a great many. Hie
opinion! point to a desire for water
worka but no definite plana have been
pnt forth, hut aa a wIkiIb their oplnlooa
wilt give manv a general insight Into
Ihe ijneatiiiii.
bonds are voted tl.i- lown haa the privll*
edge ol buying Uie ground. What thm,
on tliu oibsr hand, wlll become of it II
the water bond laeue la quashed? The
the town will have sunk one thousand
dollars without hope of return unless
they have the privilege ol buying tlie
ground wheihor lire homla aro voted or
not. But tl Una Is the eaae why did
they not sink ai.nn (300 more and own
tbe lot. It would bare been a good
investment uoder any circa nn lance.
Tbe UM-.!,- tlie Board took in lbe
first place larefereno* toJouea' aorks
• ■a, I ittii-k, unwarranted. Galea*
the/ Ami that the ahola plant ooukl he
Tbe New SiJ._-.l__
After a great amount Of mm v n( and
l-.'i|-.,1.,men I of a-ork, thr new n.l.-
ttalk is under way ol runs Iran ion.
It appear* thai the survey nd_|itrd hy
tit* Town Truslesa did nol uiret wilh
their apiiruvsl alter Um work of laying
tliu __!_.*> Iiad cummeticr.1. Under that
aurvey the aidewnlk otl University
Avenue between F.iiieraaii sml Itryaut
street* wuutd have beam sovrral leet
aliure the level Of th. road. Thi* wa
tint tilth t disBilTantageuUa and the Tow:
Kngirwer waa ioatruct__l to lay atakce
to roalorm to tlie old McMillan surrey
wblcb will leave the sidewalk wbeo
Ian-1 oa a mure desirable level with the
etreels. *
Before the Women's Club.
I'rofesaor Oriicga It .lured al lha ******
bvturlan Chureli Iwfore thu Woman's
_ .III, u! I'alo All,. .,-l.-li1;i. mi i 1.11,ilr I.
Handel waa ,!■-• .t-.u-l as mil wanting in
will bul aa Sunderm] In acllon by hla
power of seeing all sldea ol svsrv mhiect
ami In-ti.-.- reaatina lor Inaction at any
given moment. Hia famoua S0III04UV:
"To b* or not to be," waa nol a tialanc-
mg ol tbe moons lor am. ,■!,■ lor liia__elf
■ ■ui aqacBtioa for all the world whether
life ia worth living.
Ti,. club will probably be .-Ll
The dramatic recital to ba glean tomorrow ._'. i.i:i> evening by Slias Ho-
b*rt, under theauapicea uf tlie Woman's
Glob will undoubtedly prove of much
intercut. Mire Hobarl la a graduate of
lb* Chicago Conecrvaiury and haa toon
moat appredativelv received in tbe
Kul, as well aa in California. To 4 note
from tht- Oakland Eat/uirrr, "Miaa Hobarl clam.a tin- all,11I1,,11 ami admira-
llon of her audience, no leaa by her'
charming pereonality and sweet voice,
than by the power and scope ol her
drsmstio art."
Mies Hobart-> programme lor tomorrow evening includes selections Irotu II.
C. Brenner, Austin Dobaon and Kuger
A Raid by Thieving Tramps.
Tur-Jay nigbt three masked men, ru-
dentiy trampe, visited a wayside boarding house kept by Billy htanton or
Searsvill-*road, about llvn tnllee from
I'alo Alto. At tbe point of a revolver
one of the ihlovea took tha nm ~J
,<•--.1 the door and lied bi
tbe tree were Bnasrrred by one ot lbe
inmates of the house, he too waa bound
band and foot, alter which the thieve*
enured tbe dwelling and relieved tboae
inside of all they could liaJ.
Uncla.meJ Lellsr List.
Donald, L Reynold*. Arron
lloiisewortli, Miss Piereon, Peter J.
Hollina, Ellon Btutth. M R
liamiii. Rev. C A Lendrum, Ben
Matilda V. Txxtx, P. M.
Lost.
Al tbe 7:30 a.m. train Wednesday, a
parse containing train, gold. Suitable
reward if lell at the Ti_n» office.
Did it ever occur to yon that many
people judge yoo by the kind aad <j-__l.
Uy ol stationery j im use? Any ono can
keep stationery for Bate hut not every
'on* la qnallQed to select stock for a
critical trad*.
Blmkina make* llils his htislneea and
whsn you leave your order with bim
you will be sure lhal Kyle, finality end
price wlll be tighL
If yoa treat anything not in stock
remember that Simkins haa a dty
t and alll get it for yoo. t
J. 9. M_Cmtel. Tailor,
This efficient workman. * ho baa Uca
located at Menlo park, haa opened up
bia shop next to Hall's drug store,
where tba pobllc can get tlielr clothing
■ slaies. .tylst at the lowssl prices.
lo tha li
giro
are perta ol Jonee' plant thai could b*
used in b town water worka and bought
from him aa chsatdy aa they coald he
constructed, why then from a huslntoB
standpoint Ihey should b* boogbL
Four inch pip* sboald b* need La tbe
diminution of a aster works lor tbe
lime. I'nleasthis _sdon«ldonotsee_iow
we can gel prujirr protection from Are.
I find tbat in tuy turn it-diaie nalgbboo
hood tbo cltirens an. all Billing to vote
(or water i 1«. provided that the issuu
mil l»- _11ttt.l1 in to Kuarantc* fire protection, not only (or Unite rally —
and Waverlr street but lor tht. ....
town. This can be dour I should tbiuk
on a bond Issue uf (60.000 or perbapa
Utile mure."
"Ofc.
tagrons for lb* lown to obtain Jc
Slam, if they find they can uee
i_l,-r.-nt i.nrla ul il. Tliey should not
pay Jons*' price, for 11 ia nut worth that
10 the lown and from a buainras stand-
Km! I do not ace whr tbia i]ue*tk>n o
ylng Jones' works sliould have taken
tlie fur in il has, II we build a plant ol
our own it nmy lie at some future date
we would llml Dial we woold hare to
bay Mr.Jnii.-a out and then i imagine
we could ■'•■*■ 1 at a much lower Optra
tban it ran now be obtaioed for."
"By alt means lbe lownjsbould own
tlteir own water supply. And when tbe
'• .'.nn Is planned it should h* complete
aa d Lias ihla. I for on., would rathe: vote
for a t-' -l.l-Hi bond iaauo than lor a .__,*
ix.iii.-n,-. Tliolncreaseoftaxeatothcin-
ilivldtial iiroiierty owner would be out-
wcijth-d hy tlin ail ran lagta accruing Irom
such a plant, file protection sbould
lie given to all the town regardleea ol
locality so far aa the thickness of reside ncea ami population would warrant,'
"II tbe bonds are voted Bad th*portion
of J ..ii. a' woska thai wlll be of nee to a
town plaat ran be bought at a price an
unprejudiced arbitrator would name, it
woald he well tor Ihe lown. Even iu
the n,tiler ol sprinkling the streets a
a lown water worka would be a great
thing. However In taking Jonee' works
in consideration Ihu other small plania
an,un,111,,' town should ho rouisiubered.
If a biit price ahould be given to Jone*
the uihur uwnera ol crueller plant*
would have aright losak tba town lo
I Units. Fl
tbe only way the water boada eaa be
buy thuir pump an
drift ol public o[.it
1 that
led la by ignoring lb* matter of
loam* plant or the matter ol any other
watcrsnpply now tn riistenre."
a. o. urxm.
el-ooid 11.ink that tbe Iowa of Palo
Alto In putting In watar worka would
do the right tiling in paying Mr. Jons*
lor hla water plant only auch a price as
would be justillahle both as lo the actual
cost ol tim plant and as to tbe actual or
practical na* 10 wblch hla system could
to used hy the aaid lown.
The towneould hardly be warranted
for
a' hi and proper that the town should
a lbe plant if a fair price can b* arranged. II there are porta of Joae*'
system that cannot he nlilised, reject
tbem by all means. Bal it woald »j-
Kr that t-vt-ii if tbe main juj .■ Is not
j* enough for fire pings, etc.. il oouhl
he usod In otber place* and then-lore it
would nol ho a lose to the town It Ihey
should tmy iu"
a, a. runtil-»ox.
Ths town should own Ita ban walur
works. Private individual* hare fslled
to give ua sufficient water to protect ua
- >ul fire. Tbo town should ptir-
of tlie dialing water concern al a
Blnatioa ao much of Ibeir plant
id bs need in the mntlractioa and
of the new *y atriii."'
The town water worka is Bbsolulclr
asciaaary, without audi we can not look
foe any material growth. Am tu WMf
ol issuing bonds tu tin extent nl t'-i.-
QpO. The town, tan afford to Leaiiu asltl
bonds without any incrcaM. ol tax .tlon.
This would give Ihu to mu ol I'slo Alto a
good water system and iir.i-.l_a> lire
protection. Aa to tbe purchasing ol
any water works noWtn eiislem-u. sat
in favor of purchasing any or all rsiat-
ing plants al a fair price tliat could b*
used m connect-on wilh a town system."
■ Ol.ll.- UlllBI
Ma. Eoivoa: Following Is the atate-
iiimi which came too lata to he read al
special Trustee meeting of Will MP bat
S3rd, and wsa pix-jmn.t Iur the pur|mso
ul making clear lo thu Board the esact
amount ol money invested In the aaid
waler plant:
Ta (As _/_ .or..--- Board ef TrotUtt
■ t I'u ru. -.. lYf.,;, .!,■;■.
Oeatkaare la teplr to t_v* •***< "'.***
laa iba aaaa aa aaoataa lbe l_.loa.a« aaawaaia
rraMi IBS soarm mrciiisr..
) K reikfaia-a plant Janr tto -...-Jl.tJ.
Kpleai Baak alvca lai balance |>ai-
ehaae ptite .1 faiklaaou i.lael - . I^aa
CaaBtK,li«iac-ll<ioaah]oa llutihlaaat
. aa_ lut aal. -.ik'.i in'__."." a,I.. l_iiy "iful - '«"
Cat* It.-a aale nt la. lola la I'al.. All,.. r*»
f.,,1, iwtiowpj Ira*
.-I-,.1- r'._»e«_-J
Manhaltaa Sajg Pood tnehae hena lay.
Never be without it If yo-.lesire healthy
foBia. Ban Bbu. Potltbt I_.rnoir will
poaitiTcly core Koap, I'auker. DipL.-
tberia. eorc Kjc*. awellrd Ht*l and
gape. B. P. Manhope scent at Palo
Alto.
and throat, looludlag the fitting ul
MM. All examination* free. Hoom*
Earle A Suiter's grocery. Hoars
frum I u, 8 p. ni.
Piano br __*e.
A Bcatty'a best Piano direct from Ibe
factory tor sal,- lor 11 •*> cash. Too par
Ihr iii-mlii. Instrument guarantR-d.
Call or addreae, Tihrb oflloe, Palo Allot
Atitnilon.
Tbo local lour hundred shave and bare
iin-ir hair i.iiiiim-.l In thn fashi.mshie
slid most improved style* at Ufani'*
tihaviug Parlor. Uiv* u« a trial. Two
couipcteni workmen In constant atten-
daace. Nest to Parklnaoa'a.
Town Lots lor gale.
Bakereficld, Cal., ova-
Laundry Wotk.
The Stanford Univsrslly gleam Laundry liaa cbangMl hands and is now
ready for bus 1 area. All kind* ol work
done at greatly reduced price*. Laundry called for or may b* left at Mmth
ft l.y man'* trait store. First class work
guarantacd. t
.__■_.
ftiat'.-i-iacaialiiiaa. and ....
a.Ml1l»aalec|.eadllafc IBUIt 1»]_r. Sit iJaaa.
tt. . ailt^uaei tally all^bt .<*_. ul 1-al.i ah-
^"1
ipptyot
■I'll- 1 - .- -. ni-,-.: ol i - . - I.., 1.
realty ia Ihr jSaat.
TBe l....|.> ..1 rale Alio I. . 11 aa
...o-US.
a-wauaalt,.i>> i«, -'i
■nllli'i (mainly a.iukl
I t.niU Wima,
anl i_,-. (u.i a. 1 r-i.r banlS aollaa
taaaafOM IBS flam 1. t_ij-ln» ,al .,<at ua (He
hmUmLj MsUneata my pnptstnulM *t *
talauaa uui> Bate ptHT.g, by |Hi,aal*r ul aiaal.
— iBaoaMlr. 1 a*>
ot I via- of »f.
atieralti-T "1
. ,|.al ,. ■ ,| 'III,.,:, Tb.t
«.-_..
*******
** T^u't'-il.'i't. aa-i
xttfjtm
r.jaai
1 bava base aakeil by s*Teral prouil-
neiii men In lown to make a stateiiirnl
throu||li the columns nf the Tihbs, aa lo
lust what I can do nitont lire-protection.
In reply Bill _1iv, llinrr'am ready* ami
willing tu lay tha proper sired pipea
with tlio latest improved fire plugs loca-
II yoa with lo ore yotit bora* pick up
in flcth BO 1 working |-«cr, letd Manhattan lied Ball Brim) .lock Food. It
is also excellent for ixiaa, making more
and richer milk. B. P. btanholio, I'alo
Alio.
Rooms to Unit.
Itoom* asd Board.
At The Bryant Table hoard a
specialty.
Immense
Display
of Holiday Goods
FERGUSON'S
HOLIDAYS
IN ORDER TO MAKE ROOU FOR SOME
' NEW STOCK
At 50% Reduction
You will need sonic for your fancy work.
B, F, Hall's, PALO ALT&
MMB-SEl
HIT,' GRAIN MD MIUSTUFFS
WOOD ■*■ COAL
Delivered at Lowest Market Rates
General Expreia work
■ nd Hauling lollalted
Pacific Coast Agents Magee Fufnace Co.
TISN1N0
PLUMB1NU
JOBBING
SLATISO
OALVANIEBD
IRON AND
-COPPER WORK
E le Ctrl o n I work
by Competent
workmen.
MANGRUM & OTTER,
SAN JOSK ASD PALO ALTO
Grand Displays
HOLIDAY
THE PIONEERS OF PAIO A ITO.
(SQODS
Mrs. Ostrander's
CALL AND SEE
FOR YOURSELVES
Latest in Every Kind of
NOVELTIES
TruiLxa o(th« Tuwa ol Palo Alia ,,r■!•
ao laid, oa tha aaaal aad <i*aioinar*r
urr«ui*al ts-ulc bdwten a loan ol tb»!
claaa and a awtcr ,i.,_|.int. I oak I
&oU_iD( anuraai or aartoaonatilr. I
will im I.-**- tbe raj.jitv of watof 1-v
alnklnc toon Bells aa tlia paatli ol tt.o
town deman-la and niaintain auiple
|iii-m.i- id all pipca.
fil-BlW. tillllv.
_ C. W.JoNU.
'/•„ i_. Palo Al,o Timet.
Tba tol lowing
ia iHiyinj _ooi___Id_: ol aaybodr
which ttoy couU bam 00 pracucai
No doaU a xnxt ami a\ Mr
Stat caald ba aasd by thn aaid lown
l tiBtdl)- in lia praarnt _oc___ion and
tba town abould eooaidcr tba ooat of
Ur. Junt-a' plant and tba coat ol t _uj_ v-
ing tbn aaid plaitl tu audi a placa wbcrv
tim town ..niU mi«.__ practical oae of
bis watar works ejrstatn. I aboald to
beartlljr In favor ol bonding tbe Tows
of Palo Alto for * watar worka 1yat.n1
and aucb a aratam tbat will not only
•tin us good watar but alao ampla Br*
pro Uk tlon.
Ilwaaipacl our town to grow and
advancB a* ninal glio tbe pcopU wbo
itimt hrtr toot* Indacaaitcnia, aod tberr
ara no nort i_Ju,..n„t: to a town
ibsn to bBTe good water, pla&ty of 11;
aewna and a good Ilia protection."
I bava beau considerably disappointed
by tba way In wblch tba water works
question hss- been dealt with. Soma
timt) ago a uelltlun waa brought tome,
therceultol ______ I _ipoct__t would b*
a diacuaaion not a doing away witb dls-
-imaiuii of the .aier works. I ii.i not
think adviubto any action by the Town
Board In expanding large tuan of
biiiuv 111 «i triii pti Oi to aotabliah a
■j-atrtn toton Oral sulicsilltci tt to tba
********; bK_u.ee M-MIOMtet sction,
appareotly to lore* tfiopeopie in lavor
oIb aysum aboat abicli-ibey bare not
been oonenltad, la llablb lo crt-»i. a
ir.jn.lir. Id tin*ir n_lnda And so defeat
be very olijrot lor- wltioii tbe question
ru flrat brought forward—name Ir, the
telatilliliwent of public water worn. I
think tbe Aral tiling tbat sboald now be
doae * on W I- to bring the ni*:i_r before the people tor public d___ujnlon.
a. 1. ts .KE.
"Tha town thou Id by all taesns have a
waUr wotkaol tbara owe. Bat when
Lbe people rams lo vote lor bonds ll.e;
aboald know e_e_tly how mnch mottey
~re*nmry. An nnder t_aoe ar an
laaoeof booda aboald be avoided.
Tbe pricea given by Ibe tbree arbltra*
ton la Ute matter ot tba Jonee' water
plant appeared either to be unfair
- Jonas or to the town, It it
civliltetl world respects. »ill.I am sure,
ba more Intaraaung lo yonr m.lrra
than anytliing tbe Political Equality
C'lnbol PbIo Alto ia able to aay In *• -
aj.ii.i. u. yoor kioJ intimatioa of »,1.-
ingnMB to give Ue _<■ nun,t-i.t- publicity
I go fur all aharing the privllegea of
the Ko.rriiiuent who aaeial in beannit
Its uurdem, by no means excluding
woDieO,—Abraham Lirteoln.
In thV-vrogms ol civilltallon, woman
auffrage is sure to come.—Chatlet Hunt-
Juatica iaon the side ot woman suf-
engB.—H'ilfuiM //. Srwtatd.
I think there will to no end to tha
good tbat will -■,___ by woman aoSrag*.
oa tlte elected, 00 electkins. on—*o*rra-
until, and on woman banall — _'*_-/•
Juitire Chart.
aufferaga la _tuli.iiMi-.lly
ol good
.C.ltfl U ... Ill 1,1.
In llie adi
When your ccw'e milk la ruaninir
■hurt »ii,i tin n, il.iift forget that Han*,
hattan Food. Red lull lirand. will in-
.:•■ ! enrkb it, Tlita foo4 prevents
irea milk lever, bloody milk.
"'■iii.sii,.-'.,-. B. P. btanbop., agent
for I'alo Alto. t
PkRKINSON LUMBER & HARDWARE CO.
Builders material uf every description.
Mixed Paints, Oils, Brushes, etc.
.A.T LOWU3T 3MAJ_I____T PEIOES
MERGUIRE * BROS.
BOOKS, and FANCY d00DS
A FULL SUPPLY OF SCHOOL BOOKS
__=__g. .ertrrrs for s. _p. nATr.-sr p____?Ei_a
USIVERSITV AVKNUE,
.i|.ju. -in- Paiklnsons Hnrdwarr Store, Palo Alto.
Dally Mesalnger Sarvloa to San Franotaoo. Orsfara Imtt
at tha store will Raoelva Prompt Attention
ATTENTION L
organs:;.-.
1. »•_•_:_ .< .1 H|
» **~
Aj,,*,,
Palo lo Hotel
Pleasant suits, with Sun _H._^y
suitable for professor and wife.
Rooms of all kinds for young
ladies and gentlemen students.
Hot and Cold oatites ou each floor.
Plnno for the use of guests.
Table Board of tha beat.
ARCHITECTS & BUILDERS.
The Santa Clara Valley Mill and Lumber
Co., corner 4th and San Fernando streets,
San Jose, is the oldest and most reliable firm
in this county. Gives estimates on all descriptions of mill work includidg tanks, etc.
For quality of our work we refer yon to Halt of Records—State Ituaoe
Asylum at AfBCWf—Hotel Vcndotnv—Cky Hall—New Pcatofficc,
Dr. Decker's home in Palo Alto, and numerous private residence*.
ellow.
list-ration ol a Slate,
in as a woman nor a
an bas any •jk-cIb) funi.tl.n_.
THORS
PHOTOGRAPHER
UCRANT AVEKUE.
SAN FRANCISCO, CAL.
D.anch Studio, Unlveralty avenue,
Palo Alio.
Open Wednesday and Saturday
aasas.
You aak ay raaaoaa lor b.U.v_inj
in wotnan'a aattmp;. It sc*tta lo it,» I
almoat •*!.-* .-ieiii, axiom, that srTr***'
booaa bolder aad Lai*>**ar«r tiu^tit
bav* a voir* In tbe expenditura ol t
money w* pay, tnclndinit, aa it doaa,
Intertata tt,.- moat vital lo a human be-
n«— Floret** .Stfhtrnatslt. | Having derided to discontitlttc
..,r.__\;J™'°aaj;'.™"ta';i.«,_- >»»-«»«-i« *j«" u»-. »■- _«_
a .ajlcal ralona, an allininallon ol the njarke. the prices very low.
:SiiK';.i_:in:sr,.r&_''„nlri';^.'h«v» .«,.«.,., r.?uo_.
mast) ol lha corruption inpolltk* tbat \ from S4.BO to S3 30.
%.pf^t-_'_J,.S_U'r»*,;.. ICh™tm»l_C«ln«
aceapt th- Inaaoalltj ol tha salts as
Oaa ol naiarc'a Immutable lawa; call it
a (act tbat women are interior lo men
tn mind, morala and phjaiqae. Why
ahonld ii.i- aetlla or melerially . .. .'i
lh. subject ol so-called .Yi.n<„_'.
BlghUT Would not tbia vtry inlrru.t-
Uy ba a reason wlur every ulr*. t_g_ jduitry" »_cii.l»lnt_l by ltac.,11. tiiiitiini
ahmilil to giv.ntoiho weaker m_, not >■ follow*' "The ohj-.it ol itiial^aeu<
only lor iu own good, but (or Uio liljtli- ihall Iw to pioloal Ami'tlran labor b. *
est drnlcjHimeni ot tho race l-ltttnty. tar IR un Imporu, wblcb ahall ....
Id View ot the terrible corrutHlun ol uuately aecun. Aniarlcati iiuluairial j.ro-
ottr polllic_, ucople ask, can we msln-jtlticta-_ipiinatlbecc.mp«lltlon of foreign
tain u_iv.r_.i- luflrattaT I aay no, not i labor." There an nopv-aonal or private
wiiliuni the aid of womct.—Bit_op •:•>■ i prodla Id cunnection with lha or*aniu.-
i-rl Haten. lion and ll _ftoeUi_m! bv mrm_rrat,ip«.
Tie _______ principal 1. lhat w«__*n >■ coatribat-onaand tto ,|,itnl_iiion of iu
are nol ooly jnatitlrd, bot eihlUl tl_. poblicatiooa. Fiiat, Uorraapoodenee i*
moat exalted virlure. when Ihejr enter i aolkited regarding "Member-hip" and
on Iba eonoerna of their country, ul "Official CormpondenU." Saeond. We
isrzi Closing Out
'_•■ Athletic Goods
A. C. Pillsbur)' - Co,
Tbe Am._r_.mr, Prottttivt Tai-ff L-ȣUc
liutiiinitv. and of tbelr i.i-L- J-',i
Vutncy .. ilnt.i
P.I._l_,D«,.».W.IUW,C,""l6.M.
"Otficial CorretpondenU." Saoond. We
need and welcome oontrl button ,w lie I ber
auiall or large, to our cauae. Third, We
[mbllah a larts line of docuavauU eoear-
ng all phsatt of tha Tarlfl question.
Live Oak Stables
'. _B. Dalay
PHOPRIITOa
atat-H t'■>■"
Kf____B.Ak__&_OMa
.O^ALTO^O
■ - -. I', m. aubtt
•--— ;^^i'u.i,_...r.Vr.,vr.,,,;M,i.;.--i,,A1i;..., H<'.iur_r_rr
Parti ea oan toko the Train at
Cuidado espiritual en estudiantes de enfermería: estudio cualitativo
No full textIntroduction. Attention to the spiritual dimension of patients and families is fundamental as part of the active role of nursing professionals in satisfying the spiritual needs of patients. Objective. To understand the attitudes towards spiritual care of nursing professionals in training. Methodology. Qualitative study with content analysis, with a population of 20 higher education Nursing students, with convenience sampling. Semi-structured interviews and two focus groups were held to explore spiritual self-knowledge and the conceptions of spiritual care, using the theoretical concepts proposed by McSherry as a reference. Data was initially analyzed inductively, with help from the Iramuteq software. Results. Spirituality is considered an intrapersonal dimension in which the need to explore one’s own spirituality in recognized, in order to approach the spiritual perception of the patient. Learning about crises for the development of a personal spirituality and finding oneself through nature were part of the observed categories. Discussion. The conception of spiritual care as an intrapersonal dimension helps students differentiate between spirituality and religion. This aspect has been observable during educational practice, since there were some very religious people and others who were not. Conclusions. Reference is made to the relationship between that which is spiritual and corporeal, and though there is a difference between spirituality and religion, both concepts must be assessed personally.Introducción. La atención de la dimensión espiritual en pacientes y familias es fundamental como parte del papel activo de los profesionales de enfermería en la satisfacción de las necesidades espirituales de los pacientes. Objetivo. Comprender las actitudes frente al cuidado espiritual de los profesionales de enfermería en formación. Metodología. Estudio de abordaje cualitativo, con análisis de contenido, con población de 20 estudiantes de educación superior de Enfermería, con un muestreo por conveniencia. Se realizaron entrevistas semiestructuradas y dos grupos focales para indagar sobre el autoconocimiento espiritual y las concepciones del cuidado espiritual, tomando como referencia los conceptos teóricos propuestos por McSherry. El análisis de los datos inicialmente se hizo de forma inductiva, con ayuda del software Iramuteq. Resultados. La espiritualidad se considera una dimensión intrapersonal donde se reconoce la necesidad de explorar su propia espiritualidad para acercarse a la percepción espiritual del paciente. Aprender de las crisis para el desarrollo de la espiritualidad personal y encontrarse desde la naturaleza fueron parte de las categorías encontradas. Discusión. La concepción del cuidado espiritual para los estudiantes como dimensión intrapersonal, les permite distinguir entre la espiritualidad y la religiosidad. Este es un aspecto que se ha podido ver durante el desarrollo de las prácticas formativas, ya que se han encontrado personas muy religiosas, así como otras que no lo son. Conclusiones. Se hace referencia a la relación entre lo espiritual y lo corpóreo y aunque existe una diferencia entre religión y espiritualidad, los dos conceptos deben ser valorados a nivel personal
