2,328 research outputs found
On the Impact of Downlink Feedback on LoRa Performance
No full textRecently, the role of Low-Power Wide Area Networks (LPWANs) as enablers of the Internet of Things (IoT) is emerging. However, many concerns arise on the performance of LPWANs if higher Quality of Service (QoS) requirements are needed by certain classes of IoT services. In this work, we will focus on one of the most prominent of these technologies, i.e., Long-Range (LoRa). Our aim is to study to what extent a LoRa network is able to support uplink (UL) traffic that requires to be confirmed by the Network Server (NS). The simulation results show that the network performance is severely impacted by the downlink (DL) traffic generated by feedback packets
Activity of a peptide deformylase inhibitor LBM415 (NVP PDF-713) tested against recent clinical isolates from Japan
No full textCopyright © The British Society for Antimicrobial Chemotherapy 2005; all rights reserved.Jan M. Bell, John D. Turnidge, Matsuhisa Inoue, Shigeru Kohno, Yoichi Hirakata, Yasuo Ono and Ronald N. Jone
Kohno, M.
No full textPassport photo of older man. Negative scan.In 1922, Kinso Ninomiya opened the Ninomiya Studio in Little Tokyo, Los Angeles. Due to Executive Order 9066 in 1942, the studio was forced to close but was reopened by Kinso and his son, Elwin Ichiro, in 1949. The studio operated in Little Tokyo until its final closing in 1986. The Ninomiya Studio Collection captures slices of Japanese American life in Los Angeles from the 1950s through the 1980s. The collection contains formal portraiture and candid photography in black and white and color as well as commercial photography for local businesses and reproductions of older photographs. The negatives come in a variety of sizes, including 8 x 10 inch negatives and panoramic negatives on Cirkut film. Each negative scanned has been selected out of multiple negatives and prints from a set. The title of the negative scan reflects the purchaser’s name
Orbit configuration spaces associated to discrete subgroups of PSL(2,R)
No full textAbstractThe purpose of this article is to analyze several Lie algebras associated to “orbit configuration spaces” obtained from a group G acting freely, and properly discontinuously on the upper half-plane H2. The Lie algebra obtained from the descending central series for the associated fundamental group is shown to be isomorphic, up to a regrading, to 1.the Lie algebra obtained from the higher homotopy groups of analogous constructions associated to H2×Cq modulo torsion, as well as2.the Lie algebra obtained from horizontal chord diagrams for surfaces. The resulting Lie algebras are similar to those studied in [T. Kohno, Linear representations of braid groups and classical Yang-Baxter equations, Contemp. Math. 78 (1988) 339–363; T. Kohno, Vassiliev invariants and de Rham complex on the space of knots, Contemp. Math. 179 (1994) 123–138; T. Kohno, Elliptic KZ system, braid groups of the torus and Vassiliev invariants, Topology and its Applications 78 (1997) 79–94; D.C. Cohen, Monodromy of fiber-type arrangements and orbit configuration spaces, Forum Math. 13 (2001) 505–530; F.R. Cohen, M. Xicoténcatl, On orbit configuration spaces associated to the Gaussian integers: homology and homotopy groups, Topology Appl. 118 (2002) 17–29; E. Fadell and S. Husseini, The space of loops on configuration spaces and the Majer-Terracini index, Topol. Methods Nonlinear Anal. J. Julius Schauder Center 11 (1998), 249–271; E. Fadell and S. Husseini, Geometry and Topology of Configuration Spaces, in: Springer Monographs in Mathematics, Springer-Verlag, 2001; F.R. Cohen and T. Sato, On groups of morphisms of coalgebras, (submitted for publication)]. The structure of a related graded Poisson algebra defined below and obtained from an analogue of the infinitesimal braid relations parametrized by G is also addressed
Gas phase ion formation from a liquid beam of arginine in aqueous solution by IR multiphoton excitation
No full textJun-ya Kohno, Namiki Toyama, Mark A. Buntine, Fumitaka Mafuné and Tamotsu Kondowhttp://www.elsevier.com/wps/find/journaldescription.cws_home/505707/description#descriptio
Design of the Grand Roof at Tokyo Station
No full textp. 1242-1253This paper describes the design method of long and unique shape membrane structure in
capital Tokyo. The membrane structure, designed to create an impression of Japan's
traditional Washi paper, forms gentle curves of varying size and inclination, to become the
new face of the Yaesu side of the Tokyo Station. To achieve such a light membrane
structure in Japan where many natural disasters such as earthquakes and typhoons occur frequently, we adopted some ideas in order to solve technical problems.Sadamoto, M.; Yoshie, K.; Kohno, T.; Muraoka, T.; Takanashi, M. (2010). Design of the Grand Roof at Tokyo Station. Editorial Universitat Politècnica de València. https://riunet.upv.es/handle/10251/706
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Comment on “Theory of Current-Driven Domain Wall Motion: Spin Transfer versus Momentum Transfer”
No full textA Comment on the Letter by Gen Tatara and Hiroshi Kohno, Phys. Rev. Lett. 92 086601 (2004). The authors of the Letter offer a Reply.</p
p73 independent of c-Myc represses transcription of platelet-derived growth factor beta-receptor through interaction with NF-Y
No full textWe recently reported that c-Myc represses the transcription of platelet-derived growth factor (PDGF) beta-receptor (Izumi, H., Molander, C., Penn, L. Z., Ishisaki, A., Kohno, K., and Funa, K. (2001) J. Cell Sci. 114, 1533-1544). We demonstrate here that the p53 family protein p73alpha represses PDGF beta-receptor transcription essentially by the same mechanism. p73alpha but not p73beta or p53 represses the transcription in concordance with its ability to bind NF-YC and NF-YB. None of other p73 isoforms (i.e. p73beta, p73gamma, p73epsilon), C-terminal deletion mutants of p73alpha, and p53 is able to bind NF-Y with the exception of p63alpha. This finding suggests that the sterile alpha-motif domain present only in p73alpha and p63alpha is the interaction site. For the repression, the N-terminal transactivation domain of p73alpha is also indispensable, arguing for the importance of the activity of p73alpha in the mechanism. p73alpha binds the C-terminal HAP domain of NF-YC previously found to be the interaction site with c-Myc and TBP. Because c-Myc induces and activates p73alpha (Zaika, A., Irwin, M., Sansome, C., and Moll, U. M. (2001) J. Biol. Chem. 276, 11310-11316) and they bind each other (Uramoto, H., Izumi, H., Ise, T., Tada, M., Uchiumi, T., Kuwano, M., Yasumoto, K., Funa, K., and Kohno, K. (2002) J. Biol. Chem. 277, in press), we examined whether the repression by p73 is dependent on c-Myc. However, Myc-null rat fibroblasts are also susceptible to p73alpha-induced repression. Serum stimulation of NIH3T3 cells gradually decreased the amount of endogenous NF-Y binding to the PDGF beta-receptor promoter, whereas NF-YA expression in the nuclear extracts remains unchanged. Our results indicate that serum stimulation induces c-Myc and p73alpha, leading to the down-regulation of PDGF beta-receptor expression by repressing its transcription
Inhibition of the mitochondria-shaping protein Opa1 restores sensitivity to Gefitinib in a lung adenocarcinomaresistant cell line
No full textDrug resistance limits the efficacy of chemotherapy and targeted cancer treatments, calling for the identification of druggable targets to overcome it. Here we show that the mitochondria-shaping protein Opa1 participates in resistance against the tyrosine kinase inhibitor gefitinib in a lung adenocarcinoma cell line. Respiratory profiling revealed that oxidative metabolism was increased in this gefitinib-resistant lung cancer cell line. Accordingly, resistant cells depended on mitochondrial ATP generation, and their mitochondria were elongated with narrower cristae. In the resistant cells, levels of Opa1 were increased and its genetic or pharmacological inhibition reverted the mitochondrial morphology changes and sensitized them to gefitinib-induced cytochrome c release and apoptosis. In vivo, the size of gefitinib-resistant lung orthotopic tumors was reduced when gefitinib was combined with the specific Opa1 inhibitor MYLS22. The combo gefitinib-MYLS22 treatment increased tumor apoptosis and reduced its proliferation. Thus, the mitochondrial protein Opa1 participates in gefitinib resistance and can be targeted to overcome it
The preconditioned Gauss–Seidel method faster than the SOR method
No full textAbstractIn recent years, a number of preconditioners have been applied to linear systems [A.D. Gunawardena, S.K. Jain, L. Snyder, Modified iterative methods for consistent linear systems, Linear Algebra Appl. 154–156 (1991) 123–143; T. Kohno, H. Kotakemori, H. Niki, M. Usui, Improving modified Gauss–Seidel method for Z-matrices, Linear Algebra Appl. 267 (1997) 113–123; H. Kotakemori, K. Harada, M. Morimoto, H. Niki, A comparison theorem for the iterative method with the preconditioner (I+Smax), J. Comput. Appl. Math. 145 (2002) 373–378; H. Kotakemori, H. Niki, N. Okamoto, Accelerated iteration method for Z-matrices, J. Comput. Appl. Math. 75 (1996) 87–97; M. Usui, H. Niki, T.Kohno, Adaptive Gauss-Seidel method for linear systems, Internat. J. Comput. Math. 51(1994)119–125 [10]]. Since these preconditioners are constructed from the elements of the upper triangular part of the coefficient matrix, the preconditioning effect is not observed on the nth row of matrix A. In the present paper, in order to deal with this drawback, we propose a new preconditioner. In addition, the convergence and comparison theorems of the proposed method are established. Simple numerical examples are also given, and we show that the convergence rate of the proposed method is better than that of the optimum SOR
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