1,720,984 research outputs found
DIABETE E OSTEOINTEGRAZIONE IMPLANTARE
No full textObiettiviIl presente articolo studia, attraverso l’analisi della letteratura, gli effetti del diabete sull’osteointegrazione implantare e sulla guarigione dei tessuti molli.Materiali e metodiNegli studi sperimentali si evince che nella patologia diabetica è presente un ridotto contatto fra osso e impianto. Rispetto alla popolazione non affetta da diabete si assiste a una percentuale maggiore di fallimento implantare. La maggior parte di questi fallimenti accade durante il primo anno di carico, attribuendo la causa a problematiche microvascolari.RisultatiSebbene ci sia un alto rischio di fallimento nei pazienti diabetici, studi sperimentali hanno dimostrato che un livello di glicemia controllato incrementa il grado di osteointegrazione implantare.ConclusioniL’incremento della patologia diabetica pone numerosi problemi alla chirurgia implantare, anche se non rappresenta una controindicazione. Le complicanze del diabete possono inficiare la guarigione dei tessuti molli: è necessario effettuare considerazioni preliminari in caso di soggetti diabetici. Un controllo della glicemia e di altri fattori (per esempio emoglobina glicata) può incrementare la percentuale di sopravvivenza implantare.AbstractObjectivesTo review the literature about the effects of diabetes on implant osseointegration and soft tissue healing.Material and methodsExperimental studies have shown a reduced contact area between bone and implant in diabetes. Compared with the general population, a higher rate of implant failure has been seen in diabetic patients. Most of these occur during the first year of functional loading, seemingly because of microvascular complications.ResultsAlthough there is a higher risk of failure in diabetic patients, experimental studies have shown that the degree of implant osseointegration improves with a good control of blood glucose levels.ConclusionsThe increasing prevalence of diabetes mellitus has become implant therapy problem but is not a contraindication. The diabetic complication compromise the healing of soft tissues: it is necessary to take certain special preliminary considerations into account for the placement of implants in diabetic patients. A good control of plasma glycaemia, together with other measures (for example glycosylated hemoglobin), has been shown to improve the percentages of implant survival in this patients
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
C1 INH concentrate in the therapy of hereditary angioedema
No full textTen acute attacks were managed in nine patients with hereditary angioedema by means of the infusion of a C1 INH concentrate produced on large scale. No side effects were observed
Cardiopulmonary by-pass in a patient with acquired C1 inhibitor deficiency
No full textC1 inhibitor (C1-INH) regulates, complement, contact system, coagulation and fibrinolysis. Bleeding complications during cardiopulmonary bypass (CPB) have been described in a deficient patient. We report a 72 year old man affected with acquired C1-INH deficiency who successfully underwent CPB
Systemic Capillary Leak Syndrome: Is Methylene Blue the Silver Bullet?
Full text linkBackground. Systemic capillary leak syndrome (SCLS) is a rare disorder characterized by unexplained, recurrent episodes of transient, abrupt increase in endothelial permeability, leading to severe hypotension, generalized edema, and hemoconcentration. Case Report. We report the case of a patient suffering from systemic capillary leak syndrome and present a possible interpretation of the pathophysiology of this condition. Besides the classical triad of hypotension, edema, and hemoconcentration, we recorded increased levels of methemoglobin, an index of NO overproduction. We present a possible interpretation of the pathophysiology of this condition based on the fast and complete reversal of symptoms after methylene blue administration (which opposes NO-induced effects) and speculate that increased NO levels could be implicated in the pathophysiology of the capillary leak phase.
Why should an emergency physician be aware of this? The safety of this treatment and its fluid- and cathecolamine-sparing effect deserve consideration and further research
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
The systemic capillary leak syndrome : appearance of interleukin-2-receptor-positivecells during attacks
No full textAppropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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