423 research outputs found
Chronique Jurisprudence administrative française intéressant le droit de l'UE - Le juge administratif applique les réserves à un traité international sans pouvoir en examiner la validité
No full textInternational audience(CE, ass., 12 oct. 2018, n° 408567, Sarl Super Coiffeur, Lebon avec les conclusions ; AJDA 2018. 1991 ; ibid. 2390, chron. C. Nicolas et Y. Faure ; D. 2019. 678, obs. J.-M. Pastor, note E. Belliard et M. Grange ; ibid. 347, obs. O. Boskovic, S. Corneloup, F. Jault-Seseke, N. Joubert et K. Parrot ; RFDA 2018. 1161, concl. C. Touboul ; Constitutions 2018. 554, chron. L. Domingo
Chronique Jurisprudence administrative française intéressant le droit de l'UE - Le juge administratif applique les réserves à un traité international sans pouvoir en examiner la validité
No full textInternational audience(CE, ass., 12 oct. 2018, n° 408567, Sarl Super Coiffeur, Lebon avec les conclusions ; AJDA 2018. 1991 ; ibid. 2390, chron. C. Nicolas et Y. Faure ; D. 2019. 678, obs. J.-M. Pastor, note E. Belliard et M. Grange ; ibid. 347, obs. O. Boskovic, S. Corneloup, F. Jault-Seseke, N. Joubert et K. Parrot ; RFDA 2018. 1161, concl. C. Touboul ; Constitutions 2018. 554, chron. L. Domingo
Charm hadron properties in 360 GeV/c π-p interactions
No full textA study of the properties of charm particles produced in 360 GeV/c D ,F, Lambda c ,D, correlations between charm particles) are given
Overlap of diseases underlying ischemic stroke - The ASCOD phenotyping.
No full textBACKGROUND AND PURPOSE:
ASCOD phenotyping (A, atherosclerosis; S, small vessel disease; C, cardiac pathology; O, other causes; and D, dissection) assigns a degree of likelihood to every potential cause (1 for potentially causal, 2 for causality is uncertain, 3 for unlikely causal but disease is present, 0 for absence of disease, and 9 for insufficient workup to rule out the disease) commonly encountered in ischemic stroke. We used ASCOD to investigate the overlap of underlying vascular diseases and their prognostic implication.
METHODS:
A single rater applied ASCOD in 405 patients enrolled in the Asymptomatic Myocardial Ischemia in Stroke and Atherosclerotic Disease study.
RESULTS:
A was present in 90% of patients (A1=43% and A2=15%), C in 52% (C1=23% and C2=14%), and S in 66% (S1=11% and S2=2%). On the basis of grades 1 and 2, 25% of patients had multiple underlying diseases, and 80% when all 3 grades were considered. The main overlap was found between A and C; among C1 patients, A was present in 92% of cases (A1=28%, A2=20%, and A3=44%). Conversely, among A1 patients, C was present in 47% of cases (C1=15%, C2=15%, and C3=17%). Grades for C were associated with gradual increase in the 3-year risk of vascular events, whereas risks were similar across A grades, meaning that the mere presence of atherosclerotic disease qualifies for high risk, regardless the degree of likelihood for A.
CONCLUSIONS:
ASCOD phenotyping shows that the large overlap among the 3 main diseases, and the high prevalence of any form of atherosclerotic disease, reinforces the need to systematically control atherosclerotic risk factors in all ischemic strokes
Etude comparative des interactions de mesons pi- de 9 GeV/c sur deuton et neutron avec production de quatre particles chargées
No full textProposed noncryogenic, nondrag-free test of the equivalence principle in space
No full textEver since Galileo scientists have known that all bodies fall with the same acceleration regardless of their mass and composition. Known as the Universality of Free Fall, this is the most direct experimental evidence of the Weak Equivalence Principle, a founding pillar of General Relativity according to which the gravitational (passive) mass m(g) and the inertial mass m(i) are always in the same positive ratio in all test bodies. A space experiment offers two main advantages: a signal about a factor of a thousand bigger than on Earth and the absence of weight. A new space mission named GALILEO GALILEI (GG) has been proposed (Nobili et al., 1995 [J. Astronautical Sciences, 43, 219]; GALILEO GALILEI (GG), PRE PHASE A REPORT, ASI (Agenzia Spaziale Italiana), September 1996) aimed at testing the weak Equivalence Principle (EP) to 1 part in 10(17) in a rapidly spinning (5 Hz) drag-free spacecraft at room temperature, the most recent ground experiments having reached the level of 10(-12) (Adelberger et al., 1990 [PhRvD, 42, 3267]; Su et al., 1994 [PhRvD, 50, 3614]). Here we present a nondrag-free version of GG which could reach a sensitivity of 1 part in 10(16). The main feature of GG is that, similarly to the most recent ground experiments, the expected (low frequency) signal is modulated at higher frequency by spinning the system, in this case by rotating the test bodies (in the shape of hollow cylinders) around their symmetry axes, the signal being in the perpendicular plane. They are mechanically suspended inside the spacecraft and have very low frequencies of natural oscillation (due to the weakness of the springs that can be used because of weightlessness) so as to allow self-centering of the axes; vibrational noise around the spin/signal frequency is attenuated by means of mechanical suspensions. The signal of an EP violation would appear at the spin frequency as a relative (differential) displacement of the test masses perpendicularly to the spin axis, and be detected by capacitance sensors; thermal stability across the test masses and for the required integration time is obtained passively thanks to both the fast spin and the cylindrical symmetry. In the nondrag-free version the entire effect of atmospheric drag is retained, but a very accurate balancing of the test bodies must be ensured (through a coupled suspension) so as to reach a high level of Common Mode Rejection and reduce the differential effects of drag below the target sensitivity. In so doing the complexities of a drag-free spacecraft are avoided by putting more stringent requirements on the experiment. The spacecraft must have a high area-to-mass ratio in order to reduce the effects of nongravitational forces; it is therefore a natural choice to have three pairs of test masses (in three experimental chambers) rather than one as by Nobili et al. (1995) [J. Astronautical Sciences, 43, 219] and the mission called GALILEO GALILEI [PRE PHASE A REPORT, ASI (Agenzia Spaziale Italiana), September 1996]. The GG setup is specifically designed for space; however, a significant EP test on the ground is possible-because the signal is in the transverse plane-by exploiting the horizontal component of the gravitational and the centrifugal field of the Earth. This ground test is underway. (C) 1998 Elsevier Science B. V
Atherogenic Dyslipidemia in Patients With Transient Ischemic Attack
No full textBackground and Purpose-There is mounting evidence that atherogenic dyslipidemia (ie, low high-density lipoprotein cholesterol combined with high triglyceride concentrations) is an independent predictor of high cardiovascular risk and possibly of stroke. Methods-All patients included in the SOS-TIA cohort underwent an initial standardized evaluation, including medical history, physical examination, routine blood biochemistry, and diagnostic testing, and were followed for 1 year. Lipid profile was evaluated under fasting conditions. Atherogenic dyslipidemia was defined as high-density lipoprotein cholesterol blood concentration = 150 mg/dL. Results-Among 1471 consecutive patients with transient ischemic attack (TIA) or minor stroke, overall prevalence of atherogenic dyslipidemia was 5.8%, but varied from 4.6% to 11.1%, depending on final diagnosis (possible TIA or TIA with a cerebral ischemic lesion, respectively). Prevalence of atherogenic dyslipidemia was independently associated with male sex, diabetes, and body mass index, but not with ABCD2 score. Atherogenic dyslipidemia also strongly associated with symptomatic intracranial stenosis >= 50% (adjusted odds ratio, 2.77; 95% CI, 1.38-5.55), but not with symptomatic extracranial stenosis >= 50% (adjusted odds ratio, 1.20; 95% CI, 0.64-2.26). Despite appropriate secondary prevention treatment, 90-day stroke risk was greater in patients with versus without atherogenic dyslipidemia (4.8% versus 1.7%; P=0.04). Conclusions-The atherogenic dyslipidemia phenotype in patients with TIA may be associated with intracranial artery stenosis and higher risk of early recurrent stroke. Additional data are needed to confirm these findings and to assess the best way to reduce important residual risk in such patients. (Stroke. 2011;42:2131-2137.
GC-MS of 4 commercial perfumes
No full text<p>GC-MS data from 4 commercial perfumes</p>
<p>Four commercial perfumes were purchased and stored at 12 °C: Black opium from Yves Saint Laurent (France), Poison Girl from DIOR (France), 212 SEXY from Carolina Herrera (New york, USA) and 24 FAUBOURG from HERMES (France). The analysis of the four perfumes was performed using an Agilent 7890B GC, equipped with a Supelcowax 10 capillary column (30 m, 0.25 mm i.d., 0.25 µm film thickness) and coupled to a mass spectrometer 5977 Agilent Technologies. Helium was chosen as carrier gas at a flow rate of 1.3 mL/min. Column temperature was initially fixed at 40 °C for 2 min, then gradually increased to 240 °C at 3 °C/ min, and finally 240 °C for 5 min. For GC-MS detection an electron impact source was used with an ionization energy fixed at 70 eV. Data were acquired using full scan mode with a <em>m/z</em> range from 30 to 450. The perfumes were diluted 1:10 (v:v) with ethanol and 1.0 µL of the diluted samples was automatically injected in split mode (split ratio 100:1). Injector and detector temperatures were set at 250 and MS source at 230 °C, respectively. Agilent G1701EA MSD Productivity ChemStation Software Version E.02.02 was used to manage analysis.</p>
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