7,092 research outputs found
Fine structure of the secretory and sensory organs on the cephalon and the first pereionite of Trichoniscus alexandrae Caruso (Crustacea, Isopoda)
No full textTrichoniscus alexandrae Caruso is a blind troglobiont isopod; males possess secretory and sensory organs on the cephalon and 1st pereionite consisting of cuticular pits hosting a tuft of setae and gland openings. Such organs are absent in females. Three types of cuticular structures have been observed: (a) lamellar setae, which likely play a role in protecting the gland openings and favouring the evaporation of secretions; (b) contact chemoreceptors, each provided with six bipolar sensory cells, a scolopale cell and enveloping cells; (c) a secretory cell complex, consisting of a long cylindrical slender duct-forming cell, with the function of transporting to the cuticular surface a secretion produced by two deeper secretory cells. The duct-forming cell is characterized by the presence of numerous microtubules in its cytoplasm, and is provided with a flattened duct. It is suggested that the secretion produced by the secretory cells could serve for sex-recognition
Erratum to: Effects of nutraceuticals on quality of life and sexual function of perimenopausal women (Journal of Endocrinological Investigation, (2017), 40, 1, (27-32), 10.1007/s40618-016-0500-2)
No full textUnfortunately, one of the co-author first name was wrongly published in the original version. The complete correct name of the co-author is given below. A. M. C. Rapisarda. The original version of this article is also updated
M. A. Caruso and Harold Watson Inspecting Flood Damage Done to the South Caddo District Warehouse
No full textPhotograph of M. A. Caruso, supervisor and Harold Watson, District Manager of the South Caddo Soil Conservation District inspecting flood damage done to the South Caddo District warehouse. People shown in photo go as followed from left to right: 1. M. A. Caruso, 2. Harold Watson. The back of the photograph proclaims, "Supervisor M. A. Caruso and District Manager Harold Watson of the South Caddo Soil Conservation District survey damage to seed and fertilizer in the district warehouse after the flood.
Le Società Benefit: un’analisi quantitativa
No full textIl capitolo analizza empiricamente le determinanti della trasformazione in società benefit
Clarification of Cliff and Caruso (1998)
No full textIn response to N. Cliff and J. C. Caruso (1998), the author clarifies that it is the sum of the reliabilities of the components that remains invariant under rotation in reliable component analysis
Via Caruso-ex Area Scheibler. Una villa affacciata sull'Auser?
No full textVia caruso-ex Area Scheibler. A Roman villa over the Auser river?
The archaeological surveys conducted between 1993 and 2002 in via Caruso, on the outskirts of Pisa, pointed out the long continuity of life of the area from the Iron Age until Middle Age. In particular, the result of a preliminary study of Roman age finding is enough to Hypothesize the exsistence of a complex building, probably a suburban villa
Changes in polyamines, c-myc and c-fos gene expression in osteoblast-like cells exposed to pulsed electromagnetic fields
No full textPulsed electromagnetic field (PEMF) stimulation promotes the healing of fractures in humans, though its effect is little known. The processes of tissue repair include protein synthesis and cell differentiation. The polyamines (PA) are compounds playing a relevant role in both protein synthesis processes and cell differentiation through c-myc and c-fos gene activation. Since several studies have demonstrated that PEMF acts on embryonic bone cells, human osteoblast-like cells and osteosarcoma TE-85 cell line, in this study we analyzed the effect on cell PAs, proliferation, and c-myc and c-fos gene expression of MG-63 human osteoblast-like cell cultures exposed to a clinically useful PEMF. The cells were grown in medium with 0.5 or 10% fetal calf serum (FCS). c-myc and c-fos gene expressions were determined by RT-PCR. Putrescine (PUT), spermidine (SPD), or spermine (SPM) levels were evaluated by HPLC. [ 3H]-thymidine was added to cultures for DNA analysis. The PEMF increased [3H]-thymidine incorporation (P<.01), while PUT decreased after treatment (P<.01); SPM and SPD were not significantly affected, c-myc was activated after 1 h and downregulated thereafter, while c-fos mRNA levels increased after 0.5 h and then decreased. PUT, SPD, SPM trends, and [3H]-thymidine incorporation were significantly related to PEMF treatment. These results indicate that exposure to PEMF exerts biological effects on the intracellular PUT of MG-63 cells and DNA synthesis, influencing the genes encoding c-myc and c-fos gene expression. These observations provide evidence that in vitro PEMF affects the mechanisms involved in cell proliferation and differentiation. (copyright) 2005 Wiley-Liss, Inc
Lymph node-derived lymphatic endothelial cells express functional costimulatory molecules and impair dendritic cell-induced allogenic T-cell proliferation.
No full textLymphatic endothelial cells (LECs) interact with different immune cells, including T cells within lymph nodes (LNs). However, direct interactions of LECs with immune cells have yet to be investigated. In vitro studies were performed to characterize primary cultures of human LECs derived from LNs in their capacity of interacting with T cells. The results show that LECs express HLA molecules and functional costimulatory molecules needed for T-cell activation. A direct binding of LECs and T cells was detected in cell cultures connected with a clustering of costimulatory molecules on the contact phase. LECs were also able to take up and process antigens. However, major histocompatibility complex class II(+) LECs fail to induce allogeneic T-cell proliferation. Interestingly, supernatants of IFN-γ activated LECs impair proliferation of T cells cocultured with allogeneic dendritic cells, suggesting an inhibitory role of LECs. Indoleamine 2,3 dioxygenase was identified as one inhibitory molecule, which may be responsible for the impaired CD4(+) T-cell proliferation. Our observations suggest a regulatory function for activated LECs on CD4(+) T cells, which may play a role in vivo in the maintenance of the critical balance between tolerance and recall responses.-Nörder, M., Gutierrez, M. G., Zicari, S., Cervi, E., Caruso, A., Guzmán, C. A. Lymph node-derived lymphatic endothelial cells express functional costimulatory molecules and impair dendritic cell-induced allogenic T-cell proliferation
Effects of losartan and chlorthalidone on blood pressure and renal vascular resistance index in non-diabetic patients with essential hypertension and normal renal function.
No full textAntihypertensive drugs can differ in target organ protection despite similar blood pressure (BP) control. We compared the effects of losartan (L) and chlorthalidone (C) on renal vascular resistance index (RVRI) in 194 grade I to II, non-diabetic hypertensive patients with increased RVRI (>0.68 m/s by echo-Doppler) but normal renal function. Patients were randomly allocated to C 25 mg/d or L 50 mg/d according to a single blind, PROBE study design. After 4 weeks of treatment, 92 patients (48 L/44 C) with BP <140/90 mm Hg were enrolled in the long-term phase of the study. After 12 months a normalization of RVRI was observed in 47 of 48 patients treated with L (97.5%) and only in 14 of 44 of those treated with C (25.8%) despite no differences in BP control. Patients whose RVRI remained elevated during C therapy underwent a 2-week washout period and then were treated with L 50 mg/d for 12 additional months. After that period 28 of 30 (95%) of patients who were nonresponders to C showed a normalization of RVRI despite no differences in BP control. In conclusion, our data suggest that treatment with L can improve renal hemodynamic and exert a protective renal effect beyond BP control in patients with hypertension
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