1,720,962 research outputs found
Valutazione del rapporto CD4+/CD8+ nei cani affetti da dermatite atopica prima e dopo trattamento con ciclosporina A : risultati preliminari
No full textUso della citometria a flusso nello studio delle popolazioni linfocitarie circolanti con particolare riferimento al ruolo dei linfociti T regolatori e in corso di dermatite atopica
No full textLa dermatite atopica rappresenta una delle patologie più frequenti in ambito
dermatologico canino. L’eziopatogenesi a oggi, come in umana, non è del
tutto compresa; si concorda che si tratti di una sindrome a eziologia multifattoriale,
dove influenze ambientali, genetiche e immunitarie concorrono a
innescare e perpetuare tale malattia. Ultimamente si è affermata l’ipotesi che
alla base dei disturbi immunitari ci sia un’alterata cascata di attivazione dei
linfociti T helper (Th) e nel particolare un’inadeguata funzionalità dei linfociti
regolatori (Treg). Un’alterazione della quantità e dei meccanismi soppressivi
di tali linfociti porterebbe a un disequilibrio del rapporto tra linfociti Th1
e Th2. La citofluorimetria, o citometria a flusso, è una metodica di laboratorio
che permette la valutazione qualitativa e quantitativa di diversi parametri
di singole cellule in sospensione. La quantificazione dei Treg con queste nuove
tecniche favorisce lo studio e la conoscenza della complessa cascata immunitaria
in corso di malattie allergiche.Canine atopic dermatitis (CAD) is one of the most common dermatologie diseases in dogs. Its etiopathogenesis is not completely clear; it is currently accepted that CAD is a multifactorial syndrome, where environmental, genetic and immunologicfactors play a role in development and progression of the disease. Recently, an abnormal activation and function of T helper (Th) contributor to immunologic dysfunction has been speculated. It is supposed that variations in number or function of Treg would lead to an altered relationship between Th1 and Th2 lymphocytes. This hypothesis would explain part of CAD etiopathogenesis. Flow cytometry is a technique that allows a qualitative and quantitative investigation of cells suspended in a solution. This technique can be used to study lympho-gtes populations, including Treg, to investigate the complex immune cascade in allergic diseases
Evaluation of CD4+/CD8+ ratio, CADESI and VAS in 15 atopic dogs before and after treatment with Ciclosporin A
No full text
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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