244 research outputs found

    Obtención y caracterización de péptidos antioxidantes a partir de proteínas de suero

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    Fil: Bettiol, M. R. Universidad Nacional de Villa María; Argentina.Fil: Ballatore, M. B. Universidad Nacional de Villa María; Argentina.Fil: Aminahuel, C. A. Universidad Nacional de Villa María; Argentina.Fil: Vanden Braber, N. L. Universidad Nacional de Villa María; Argentina.Fil: Breser, M. L. Universidad Nacional de Villa María; Argentina.Fil: Porporatto, C. Universidad Nacional de Villa María; Argentina.Fil: Cavaglieri, L. R. Universidad Nacional de Villa María; Argentina.Fil: Montenegro, M.A. Universidad Nacional de Villa María; Argentina

    Work-in-progress: Pedestrian bridge application in a fundamentals of structural analysis course inside an architecture bachelor program

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    The paper presents an application of the Problem-Based Learning (PBL) methodology in a structural analysis course taught in English of the third year Architecture bachelor program at Politecnico di Torino (Italy). This experimentation regards a class which is composed mostly of international students, that is, a heterogeneous audience with different background. In general, students struggle with the technical aspects typical of structural analysis course. PBL has been found as a possible solution to this problem in Engineering programs. The aim of redesigning the course is to support students' learning while evaluating the PBL application in a non-technical context with an international audience. This work-in-progress article explains its implementation with the first observations. In particular, the participation has increased compared to the previous academic year in terms of presence during the lectures, interest in the subject and interaction between the lecturer and the students. These preliminary results are encouraging and confirm the validity of the PBL methodology as actually applied

    Modelling the non-linear viscoelastic behaviour of brain tissue in torsion

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    Brain tissue accommodates non-linear deformations and exhibits time-dependent mechanical behaviour. The latter is one of the most pronounced features of brain tissue, manifesting itself primarily through viscoelastic effects such as stress relaxation. To investigate its viscoelastic behaviour, we performed ramp-and-hold relaxation tests in torsion on freshly slaughtered cylindrical ovine brain samples (25 mm diameter and ∼10 mm height). The tests were conducted using a commercial rheometer at varying twist rates of {40, 240, 400} rad m−1 s−1, with the twist remaining fixed at ∼88 rad m−1, which generated two independent datasets for torque and normal force. The complete set of viscoelastic material parameters was estimated via a simultaneous fit to the analytical expressions for the torque and normal force predicted by the modified quasi-linear viscoelastic model. The model's predictions were further validated through finite element simulations in FEniCS. Our results show that the modified quasi-linear viscoelastic model—recently reappraised and largely unexploited—accurately fits the experimental data. Moreover, the estimated material parameters are in line with those obtained in previous studies on brain samples under torsion. These material parameters could enhance our understanding of slow-progressing pathologies such as tumour growth or neurodegeneration and inform the development of improved in silico models for brain surgery planning and training. Our novel testing protocol also offers an efficient, robust and reliable method for determining the viscoelastic properties of brain tissue under much more rapid loading conditions, which are of crucial importance for modelling traumatic brain injury.This publication has emanated from research jointly funded by Taighde Éireann – Research Ireland under grant number GOIPG/2024/3552 (Griffen Small), and by the College of Science and Engineering at the University of Galway under the Millennium Fund scheme for the project “Modelling Brain Mechanics” (Valentina Balbi). Francesca Ballatore acknowledges support from the PNRR M4C2 through the project “Made in Italy Circolare e Sostenibile (MICS)”, CUP: E13C22001900001. The authors are grateful to the anonymous reviewers for their constructive criticisms, helpful suggestions and insights.peer-reviewe

    Stephanorhinus hundsheimensis: nuovi dati paleontologici e archeozoologici dai reperti di rinoceronte di Isernia La Pineta

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    Nel presente lavoro si riportano nuovi elementi paleontologici e archeozoologici emersi dallo studio morfologico e morfometrico dei resti di rinoceronte del rinomato sito antropico di Isernia La Pineta (Molise), del Pleistocene Medio inferiore (Galeriano Medio), attribuiti a S. hundsheimensis da Sala e Fortelius (1993). Il rinoceronte è la seconda specie più rappresentata nell’insieme faunistico e presenta tracce dell’attività antropica legata alla macellazione ed in particolare alla fratturazione intenzionale delle ossa lunghe per il recupero del midollo. Data l’elevata numerosità campionaria dei resti dentari (229 denti), la loro analisi ha rivestito un ruolo preponderante nello studio. I risultati dell'analisi frequenziale della variabilità morfologica dentaria evidenziano un forte grado di variazione regionale intraspecifica (fenomeno che, purtroppo, ne limita l'utilità diagnostica nelle determinazioni specifiche). Il materiale cranico (non dentario) non è stato analizzato in questa sede ed i resti estremamente frammentati delle ossa lunghe, pur utili per comprendere le modalità di fatturazione antropica, non sono sufficienti ad uno studio paleontologico di tipo morfologico; fa eccezione l’acropodio, ben rappresentato e costituito da elementi che, forse proprio in virtù della loro piccola taglia e quindi del loro scarso interesse nutrizionale, non sono stati frammentati ed hanno quindi consentito uno studio morfologico.Stephanorhinus hundsheimensis: new palaeontological and archaeozoological data on the rhinoceros remains from Isernia La Pineta (Southern Italy) In the present work we report new palaeontological and archaeozoological data revealed by a morphological and morphometrical study of the rhinoceros remains from the renowned anthropic site of Isernia La Pineta (Molise, Italy), early Middle Pleistocene (Middle Galerian), assigned to S. hundsheimensis by Sala and Fortelius (1993). The rhinoceros is the most represented species after the Bison and preserves traces of anthropic activity in the form of butchering marks and, in particular, of intentional fracturing of the long bones in order to extract the marrow. Given the high sample size of the dental remains (229 teeth), the analysis of the dental morphology, played a major role in this study. The results of frequency analysis of the morphological variability show a high degree of regional variation within the species in tooth morphology (a phenomenon that, unfortunately, limits its diagnostic power for the specific identification). Cranial (not dental) material is not treated here, while the fragments of long bones, still helpful to analyze the fracturing techniques, are not suitable for a morphological study. However, the acropodium, consisting in small sized elements, was not exploited for feeding purposes and is thus well preserved and its morphology has been analyzed in detail
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