915 research outputs found
Le competenze interculturali nella comunicazione mediale: interpretare per comprendere la Primavera Araba
No full textIl capitolo analizza e descrive alcune nuove competenze per l'educazione degli adulti, in particolare per i giornalisti che necessitano di una formazione specifica al fine di comunicare, con i mass media, le informazioni corrette a favore dell'inclusione. Si riflette soprattutto su un caso specifico: la comunicazione della Primavera Arab
Epidemiology of motor neuron disease in north-east Veneto region: Venice, Padua, and Belluno Provinces (1972-1981)
No full textIncidence and risk factors of motor neuron disease in the venice and padua districts of italy, 1972-1979
No full text105 patients with motor neuron disease (MND) from the Provinces of Padua and Venice were evaluated over an 8-year period (1972-1979). Average annual age-adjusted incidence rates rose from 0.49/100,000/year in 1972-1973 to 0.82/100,000/year in 1978-1979. Our epidemiologic survey showed a higher incidence in sparsely populated areas (1.7/100,000/year). A case-control study of 25 patients with MND revealed a statistically significant association with previous fractures (p < 0.01). © 1983 S. Karger AG, Basel
Residues of veterinary drugs in fish and fish products: An analysis of RASFF data over the last 20 years
No full textAn analysis of the notifications in the European Union (EU) Rapid Alert System for Food and Feed (RASFF) portal due to residues of veterinary drugs in fish and fish products over the period 2001–2021 was conducted examining the following data: number and type of notifications; year of notification; notification basis; notifying country; country of origin; action taken; distribution status; risk decision; fish product type; residue found. A total of 292 notifications were found (mean number/year 9.8 ± 13.8 SD), mostly information notifications (60.9%). The most common notification basis was “border control - consignment detained” (38.4%), followed by “official control on the market” (37.9%) and “border control - consignment released” (13.7%). Over half (54.1%) of the notifications were issued by the United Kingdom, Germany and Spain, dominant countries in the fish processing market. Thirty-one countries of origin were recorded, but 48.6% of the notifications were referred to products from Vietnam, followed by China (15.7%), that are among the leading fish producing countries. The most common actions taken were re-dispatch (23.3%), followed by recall from consumer (10.3%), withdrawal from recipients (9.9%), destruction (9.6%), and import not authorised (9.2%). Overall, 28.8% of the notifications involved fish products belonging to the Pangasiidae family (Pangasius spp. and Pangasianodon spp.), followed by tilapia (12.7%), trout (11.0%), eel (8.6%), catfish (7.9%) and salmon (3.4%). Triphenylmethane dyes and their metabolites were the most frequent category of residues found, accounting for 51.4% of the total notifications, followed by a wide range of antibiotics classes, of which nitrofurans and metabolites (19.5%) were the most common, while amphenicols (6.8%), quinolones and fluoroquinolones (6.5%), sulphonamides and potentiators (5.1%), tetracyclines and metabolites (3.4%) and other classes were less represented. Avermectins and unspecified residues were also found in a few cases (2.7%). The annual frequency of these issues varied and was probably influenced by dedicated monitoring plans, as well as by specific sanitary problems occurring in farms. Nevertheless, by providing historical trends and current issues, our analysis identified hazards to be closely monitored, through coordinated official controls especially in the most involved countries
Upper-limb robot-assisted therapy in rehabilitation of acute stroke patients: Focused review and results of new randomized controlled trial
No full textThe successful motor rehabilitation of stroke patients requires early intensive and task-specific therapy. A recent Cochrane Review, although based on a limited number of randomized controlled trials (RCTs), showed that early robotic training of the upper limb (i.e., during acute or subacute phase) can enhance motor learning and improve functional abilities more than chronic-phase training. In this article, a new subacute-phase RCT with the Neuro-RehabilitationroBot (NeReBot) is presented. While in our first study we used the NeReBot in addition to conventional therapy, in this new trial we used the same device in substitution of standard proximal upper-limb rehabilitation. With this protocol, robot patients achieved similar reductions in motor impairment and enhancements in paretic upper-limb function to those gained by patients in a control group. By analyzing these results and those of previous studies, we hypothesize a new robotic protocol for acute and subacute stroke patients based on both treatment modalities (in addition and in substitution)
Comment on “mineralocorticoid antagonism enhances brown adipose tissue function in humans: A randomized placebo-controlled cross-over study”
No full textCalcium paradox phenomenon in mammalian muscle. An experimental model for the study of pathogenesis of opaque fibers
No full textImpact of adrenal steroids on regulation of adipose tissue
No full textCorticosteroids are secreted by the adrenal glands and control the functions of adipose tissue via the activation of mineralocorticoid receptor (MR) and glucocorticoid receptor (GR). In turn, adipocytes release a large variety of adipokines into the bloodstream, regulating the function of several organs and tissues, including the adrenal glands, hereby controlling corticosteroid production. In adipose tissue, the activation of the MR by glucocorticoids (GC) and aldosterone affects important processes such as adipocyte differentiation, oxidative stress, autophagic flux, adipokine expression as well as local production of GC through upregulation of the enzyme 11 beta-hydroxysteroid dehydrogenase type 1 (11 beta-HSD1). Notably, the proinflammatory responses induced by the MR are counteracted by activation of the GR, whose activity inhibits the expression of inflammatory adipokines. Both GR and MR are deeply involved in adipogenesis and adipose expansion; hence pharmacological blockade of these two receptors has proven effective against adipose tissue dysfunction in experimental models of obesity and metabolic syndrome (MetS), suggesting a potential use for MR and GR antagonists in these clinical settings. Importantly, obesity and Cushing's syndrome (CS) share metabolic similarities and are characterized by high levels of circulating corticosteroids, which in turn are able to deeply affect adipose tissue. In addition, pharmacological approaches aimed at reducing aldosterone and GC levels, by means of the inhibition of CYP11B2 (aldosterone synthase) or 11 beta-HSD1, represent alternative strategies to counter the detrimental effects of excessive levels of corticosteroids, which are often observed in obesity and, more general, in MetS. (C) 2017 American Physiological Society
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