188 research outputs found
Il sirventese «Felon cor ai et enic» di Percivalle Doria
No full textIl contributo propone edizione e studio del sirventese Felon cor ai et enic (1258-1259), in cui Percivalle Doria mostra due aspetti salienti della sua personalità e della sua vita: il coinvolgimento politico e l’impegno poetico. L’autore elogia re Manfredi di Svevia e gli offre il suo sostegno nelle lotte per il potere in cui è implicato.
The essay offers an edition and analysis of the sirventes Felon cor ai et enic (1258-1259), where Percivalle Doria shows two distinguishing aspects of his personality and life: political participation and poetical care. The author praises king Manfredi and gives to him his support in the fights for power in which he is implicated
The Application of Micro- and Nano-Sized Zinc Oxide Particles Differently Triggers Seed Germination in <i>Ocimum basilicum</i> L., <i>Lactuca sativa</i> L., and <i>Lepidium sativum</i> L. under Controlled Conditions
No full textZinc oxide (ZnO) particles have recently received attention in different agriculture sectors as new technologies and practices are entering into force with limited adverse effects on the environment. However, various works have reported both positive or negative effects on plants. The present study focused on an evaluation of the effects of four different new micro- and nano-sized ZnO particles (namely, Desert Roses (DRs), MultiPods (MPs), NanoFlakes (NFs), and NanoParticles (NPs)) on the seed germination traits of Ocimum basilicum L., Lactuca sativa L., and Lepidium sativum L. ZnO particles were applied at concentrations of 12.5 ppm, 25 ppm, and 50 ppm. Seeds moistened with deionized water were used as a control. All the particles were characterized by field emission scanning electron microscopy, and their production of Reactive Oxygen Species (ROS) under seed germination conditions was evaluated through electron paramagnetic resonance spectroscopy. Seeds of each species were put on filter paper under controlled conditions in both dark and light photoperiods. In this bioassay, the final germination percentage (FGP), early root length, and index of germination were evaluated. The results showed a wide variability of response to the type and concentration of ZnO particles and to the applied photoperiod of the three studied species. O. basilicum FGP increased when treated with NPs and DRs already at the lowest concentration and especially in light conditions with values significantly superior to those of the control (71.1%, 69.4%, and 52.2%, respectively). At higher concentrations, phytotoxicity on root length was observed, with a reduction of circa 30% in comparison to untreated seeds. On the contrary, in L. sativum, a phytotoxic effect was seen in radicle length with all the used ZnO particles and concentrations. L. sativa seeds did not show significant effects due to the type of particles, with a reduction in FGP only at higher concentrations and particularly in light conditions. Upon light irradiation, different levels of ROS were counted by the application of ZnO particles. DRs produced the highest amount of DMPO-OH adduct (up to 2.7 × 10−5 M) followed by the NP type (2.0 × 10−5 M). Taking together all these findings, the seeds’ coat morphology, their ability to absorb ZnO particles, and the ROS production in light conditions are indeed crucial players in the application of these formulations in seed germination
Human cytomegalovirus infection of the major leukocyte subpopulations and evidence for initial viral replication in polymorphonuclear leukocytes from viremic patients
No full textFourteen immunocompromised patients were examined for viremia, pp65 and p72 antigenemia, and presence of viral DNA in leukocyte fractions of polymorphonuclear leukocytes (PMNL), monocytes/macrophages (M/M), and B and T lymphocytes after purification by fluorescence-activated cell sorting. Nearly all PMNL and M/M fractions were positive for DNA and pp65 antigenemia, while p72 antigenemia was detected in 73% and 62%, respectively. The virus isolation rate was 45% from PMNL and 17% from M/M. T lymphocytes were positive for DNA in 50% of cases and for pp65 and p72 antigenemia in only 11%, while B lymphocytes were DNA-positive in 43% of samples and consistently negative for antigenemia; neither T nor B lymphocytes had virus isolated. Immediate-early (IE)1 RNA was present in 23 (85.2%) of 27 dextran-enriched DNA-positive p72-positive PMNL samples and, in sequential PMNL samples from two heart-transplanted patients, was detected during peak infection in association with p72. Thus, PMNL and M/M are the subpopulations primarily involved in HCMV infection; PMNL may undergo IE replicative events and are not merely passive carriers of phagocytized viral material
Cytomegalovirus prophylaxis by intravenous immunoglobulinis in five heart transplanted patients
No full textThe present study was set up to evaluate the efficacy of hyperimmune anti-CMV immunoglobulins (IVIG) in the prophylaxis of CMV infection in five patients suffering from dilatative myocardiopathy and submitted to hearth transplant. Different commercial IVIG were tested for anti-CMV neutralizing antibodies before administrated them to patients; the lots immunochemically prepared by PEG resulted to have the highest anti-CMV titer. IVIG treatment, when administered at high doses and at closes intervals of time, proved able to prevent and control CMV infections, when treatment was stopped, a primary infection occurred, easily conrolled by short courses of DHPG. Even if our survey ws limited to only five cases, it soould be emphasized that after the suspension of the therapy, clinical symptoms were restricted to simple mononucleosis syndrome without organ disease. Furthermore ti shoud be noted that during IVIG therapy no immediate or delayed adverse effects were observed
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