1,721,338 research outputs found
CONCORSO "IVE" DI SOCIAL HOUSING IN VIA CA' D'ORO FAVARO VENETO, VENEZIA
No full textGli edifici sono posizionati in modo ruotato rispetto alla direzione della viabilità di scorrimento veloce di via Martiri della Libertà che lambisce l’area a est. In tal modo essi non presentano alcun fronte esposto a nord, permettendo così ai raggi solari l’illuminazione di tutte le facce. I fronti degli alloggi sono schermati da una “camicia fustellata” che avvolge il volume e che è connessa ai balconi. Tale parete schermo ha giacitura sul margine esterno dei balconi perimetrali ai corpi di fabbrica. Un sistema che dà luogo a una doppia pelle legata all’edificio.
http://www.ruggerolenci.it
Struttura monumentale a celebrazione dei Valori fondanti la Repubblica e la Costituzione e a ricordo delle Lotte di Liberazione e dei Valori dell’Europa. Tra i tre progetti selezionati
No full textL’opera d’arte proposta si inscrive nell’ambito della riqualificazione complessiva del sistema delle piazze e degli spazi pubblici centrali del Nucleo Storico di Lugo e in particolare di piazza Garibaldi. L’intento è quello di contribuire a ridisegnare il decoro complessivo della piazza con una struttura monumentale e una sistemazione delle superfici interessate, basandosi sui quattro valori individuati:
la Repubblica;
la Costituzione;
l’Europa;
il ricordo delle Lotte di Liberazione e delle sue Vittime.
Questi valori vengono interpretati in senso artistico e trasformati in quattro elementi verticali.
Quattro pilastri della nostra democrazia, articolati insieme in una sinfonia spaziale unitaria.
Pilastri che, singolarmente, vengono sottoposti a torsioni e contro torsioni, a simboleggiare attacchi di ogni tipo.
Non sono pilastri fragili, come il vetro, ma duttili.
Sono pilastri che acconsentono a opportune revisioni e riforme democratiche, ma che non cedono mai.
Anzi, ogni revisione e riforma li rafforza sempre più.
Tale aumento di forza avviene tanto singolarmente quanto coralmente.
Duttilità, non debolezza, forza carica di valori umani, non mera rigidità meccanica e freddezza informatica.
Ogni attacco ai valori democratici e alle qualità umane della cultura e della memoria non indebolisce questi quattro valori, semmai li rafforza.
Pertanto la scultura monumentale proposta per Lugo ne viene rafforzata in una spazialità plastica che diventa simbolo di un processo di aumento della consapevolezza e di affinamento della democrazia in continuo divenire.
Le certezze apodittiche e assolute delle società arcaiche vengono superate da posizioni aperte al confronto e al dialogo
Correction: Cyclophosphamide pulse regimen in the treatment of alveolitis in systemic sclerosis (Journal of Rheumatology (2002) 29 (731-736))
No full textCyclophosphamide pulse regimen in the treatment of alveolitis in systemic sclerosis. J Rheumatol 2002;29:731-6. The correct name of the co-author M. Proietti is Michele Proietti
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Phenotypic analysis and isolation of murine hematopoietic stem cells and lineage-committed progenitors
No full textThe bone marrow is the principal site where HSCs and more mature blood cells lineage progenitors reside and differentiate in an adult organism. HSCs constitute a minute cell population of pluripotent cells capable of generating all blood cell lineages for a life-time(1). The molecular dissection of HSCs homeostasis in the bone marrow has important implications in hematopoiesis, oncology and regenerative medicine. We describe the labeling protocol with fluorescent antibodies and the electronic gating procedure in flow cytometry to score hematopoietic progenitor subsets and HSCs distribution in individual mice (Fig. 1). In addition, we describe a method to extensively enrich hematopoietic progenitors as well as long-term (LT) and short term (ST) reconstituting HSCs from pooled bone marrow cell suspensions by magnetic enrichment of cells expressing c-Kit. The resulting cell preparation can be used to sort selected subsets for in vitro and in vivo functional studies (Fig. 2). Both trabecular osteoblasts(2,3) and sinusoidal endothelium(4) constitute functional niches supporting HSCs in the bone marrow. Several mechanisms in the osteoblastic niche, including a subset of N-cadherin(+) osteoblasts(3) and interaction of the receptor tyrosine kinase Tie2 expressed in HSCs with its ligand angiopoietin-1(5) concur in determining HSCs quiescence. "Hibernation" in the bone marrow is crucial to protect HSCs from replication and eventual exhaustion upon excessive cycling activity(6). Exogenous stimuli acting on cells of the innate immune system such as Toll-like receptor ligands(7) and interferon-alpha(6) can also induce proliferation and differentiation of HSCs into lineage committed progenitors. Recently, a population of dormant mouse HSCs within the lin(- )c-Kit(+ )Sca-1(+ )CD150(+ )CD48(- )CD34(-) population has been described(8). Sorting of cells based on CD34 expression from the hematopoietic progenitors-enriched cell suspension as described here allows the isolation of both quiescent self-renewing LT-HSCs and ST-HSCs(9). A similar procedure based on depletion of lineage positive cells and sorting of LT-HSC with CD48 and Flk2 antibodies has been previously described(10). In the present report we provide a protocol for the phenotypic characterization and ex vivo cell cycle analysis of hematopoietic progenitors, which can be useful for monitoring hematopoiesis in different physiological and pathological conditions. Moreover, we describe a FACS sorting procedure for HSCs, which can be used to define factors and mechanisms regulating their self-renewal, expansion and differentiation in cell biology and signal transduction assays as well as for transplantation
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