5,804 research outputs found
Intrinsic paramagnetic Meissner effect due to s-wave odd-frequency superconductivity
No full textIn 1933, Meissner and Ochsenfeld reported the expulsion of magnetic flux-the diamagnetic Meissner effect-from the interior of superconducting lead. This discovery was crucial in formulating the Bardeen-Cooper-Schrieffer (BCS) theory of superconductivity. In exotic superconducting systems BCS theory does not strictly apply. A classical example is a superconductor-magnet hybrid system where magnetic ordering breaks time-reversal symmetry of the superconducting condensate and results in the stabilization of an odd-frequency superconducting state. It has been predicted that under appropriate conditions, odd-frequency superconductivity should manifest in the Meissner state as fluctuations in the sign of the magnetic susceptibility, meaning that the superconductivity can either repel (diamagnetic) or attract (paramagnetic) external magnetic flux. Here, we report local probe measurements of faint magnetic fields in a Au=Ho=Nb trilayer system using low-energy muons, where antiferromagnetic Ho (4.5 nm) breaks time-reversal symmetry of the proximity-induced pair correlations in Au. From depth-resolved measurements below the superconducting transition of Nb, we observe a local enhancement of the magnetic field in Au that exceeds the externally applied field, thus proving the existence of an intrinsic paramagnetic Meissner effect arising from an odd-frequency superconducting state.Peer reviewe
Oral history interview with Louis Meissner
No full textLouis Meissner, a 1953 and 1956 graduate of Oklahoma A&M College, now Oklahoma State University (OSU), describes his time working as an instructor for OSU agricultural outreach program in Ethiopia. He recalls his early life growing up as the son of sharecroppers, his undergraduate experiences, and his later service in the Army. Meissner also tells about his life after returning to America and how he eventually returned to Stillwater to retire.The O-STATE Stories Oral History collection is comprised of interviews which chronicle the rich history, heritage, and traditions of Oklahoma State University
Segmentation of isotropic 3D electron microscopy (FIB-SEM) data of mouse double-innervated Meissner corpuscle (jrc_mus-meissner-corpuscle-2)
No full textSample: Double-innervated Meissner corpuscle from the forepaw of a 3-week-old C57BL/6J WT mouseSample Description: Across mammalian skin, structurally complex and diverse mechanosensory end organs respond to mechanical stimuli and enable our perception of dynamic, light touch. How forces act on morphologically dissimilar mechanosensory end organs of the skin to gate the requisite mechanotransduction channel Piezo2 and excite mechanosensory neurons is not understood. Here, we report high-resolution reconstructions of the hair follicle lanceolate complex, Meissner corpuscle, and Pacinian corpuscle and the subcellular distribution of Piezo2 within them. Across all three end organs, Piezo2 is restricted to the sensory axon membrane, including axon protrusions that extend from the axon body. These protrusions, which are numerous and elaborate extensively within the end organs, tether the axon to resident non-neuronal cells via adherens junctions. These findings support a unified model for dynamic touch in which mechanical stimuli stretch hundreds to thousands of axon protrusions across an end organ, opening proximal, axonal Piezo2 channels and exciting the neuron.This dataset contains manually proofread automatic segmentation of the FIB-SEM dataset in jrc_mus-meissner-corpuscle-2.Protocol: Samples were dissected and drop fixed in glutaraldehyde and paraformaldehyde, and then osmicated with osmium tetroxide and potassium ferrocyanide, followed by osmium tetroxide only. Samples were subsequently stained with uranyl acetate and samarium chloride. Samples were dehydrated with an ethanol series followed by anhydrous acetone, infiltrated with Durcupan resin, and cured at 60°C.Contributions: Sample provided by Annie Handler (Harvard Medical School/HHMI) and Qiyu Zhang (Harvard Medical School/HHMI), prepared for imaging by Song Pang (HHMI/Janelia, currently at Yale School of Medicine), imaged by Song Pang and C. Shan Xu (HHMI/Janelia, currently at Yale School of Medicine), post data registration by C. Shan Xu, global image alignment and processing by Annie Handler and Qiyu Zhang, automatic segmentation by Tri M. Nguyen (Harvard Medical School) under the supervision of Wei-Chung Allen Lee (Harvard Medical School), ground truth annotation by Rebecca Plumb, Brianna Sanchez, Karyl Ashjian, Aria Shotland, Bartianna Brown, Madiha Kabeer, Nusrat Africawala, Stuart Cattel, Annie Handler, and Qiyu Zhang (all Harvard Medical School/HHMI), and segmentation proofreading by Annie Handler, Qiyu Zhang, and Michael Nolan-Tamariz (Harvard Medical School/HHMI).Acquisition ID: jrc_mus-meissner-corpuscle-2Voxel size (nm): 6 x 6 x 6 (x, y, z)Data dimensions (µm): 74.1 x 55.1 x 69.6 (x, y, z)Scanning speed (MHz): 1Dataset URL (Redirect): https://data.janelia.org/gTkdEEM DOI: https://doi.org/10.25378/janelia.23969106Visualization Website: https://openorganelle.janelia.org/datasets/jrc_mus-meissner-corpuscle-2Publication: Handler et al., 2023</p
Isotropic 3D electron microscopy (FIB-SEM) data of mouse single-innervated Meissner corpuscle (jrc_mus-meissner-corpuscle-1)
No full textSample: Single-innervated Meissner corpuscle from the forepaw of a 3-week-old C57BL/6J WT mouseSample Description: Across mammalian skin, structurally complex and diverse mechanosensory end organs respond to mechanical stimuli and enable our perception of dynamic, light touch. How forces act on morphologically dissimilar mechanosensory end organs of the skin to gate the requisite mechanotransduction channel Piezo2 and excite mechanosensory neurons is not understood. Here, we report high-resolution reconstructions of the hair follicle lanceolate complex, Meissner corpuscle, and Pacinian corpuscle and the subcellular distribution of Piezo2 within them. Across all three end organs, Piezo2 is restricted to the sensory axon membrane, including axon protrusions that extend from the axon body. These protrusions, which are numerous and elaborate extensively within the end organs, tether the axon to resident non-neuronal cells via adherens junctions. These findings support a unified model for dynamic touch in which mechanical stimuli stretch hundreds to thousands of axon protrusions across an end organ, opening proximal, axonal Piezo2 channels and exciting the neuron.This dataset contains the FIB-SEM data of a single-innervated Meissner corpuscle from the forepaw of a 3-week-old C57BL/6J mouse.Protocol: Samples were dissected and drop fixed in glutaraldehyde and paraformaldehyde, and then osmicated with osmium tetroxide and potassium ferrocyanide, followed by osmium tetroxide only. Samples were subsequently stained with uranyl acetate and samarium chloride. Samples were dehydrated with an ethanol series followed by anhydrous acetone, infiltrated with Durcupan resin, and cured at 60°C.Contributions: Sample provided by Annie Handler (Harvard Medical School/HHMI) and Qiyu Zhang (Harvard Medical School/HHMI), prepared for imaging by Song Pang (HHMI/Janelia, currently at Yale School of Medicine), imaged by Song Pang and C. Shan Xu (HHMI/Janelia, currently at Yale School of Medicine), post data registration by C. Shan Xu, global image alignment and processing by Annie Handler and Qiyu Zhang, automatic segmentation by Tri M. Nguyen (Harvard Medical School) under the supervision of Wei-Chung Allen Lee (Harvard Medical School), ground truth annotation by Rebecca Plumb, Brianna Sanchez, Karyl Ashjian, Aria Shotland, Bartianna Brown, Madiha Kabeer, Nusrat Africawala, Stuart Cattel, Annie Handler, and Qiyu Zhang (all Harvard Medical School/HHMI), and segmentation proofreading by Annie Handler, Qiyu Zhang, and Michael Nolan-Tamariz (Harvard Medical School/HHMI).Acquisition ID: jrc_mus-meissner-corpuscle-1Voxel size (nm): 6 x 6 x 6 (x, y, z)Data dimensions (µm): 36.7 x 45.3 x 57.2 (x, y, z)Scanning speed (MHz): 1Dataset URL (Redirect): https://data.janelia.org/KCjtYVisualization Website: https://openorganelle.janelia.org/datasets/jrc_mus-meissner-corpuscle-1Publication: Handler et al., 2023</p
Isotropic 3D electron microscopy (FIB-SEM) data of mouse double-innervated Meissner corpuscle (jrc_mus-meissner-corpuscle-2)
No full textSample: Double-innervated Meissner corpuscle from the forepaw of a 3-week-old C57BL/6J WT mouseSample Description: Across mammalian skin, structurally complex and diverse mechanosensory end organs respond to mechanical stimuli and enable our perception of dynamic, light touch. How forces act on morphologically dissimilar mechanosensory end organs of the skin to gate the requisite mechanotransduction channel Piezo2 and excite mechanosensory neurons is not understood. Here, we report high-resolution reconstructions of the hair follicle lanceolate complex, Meissner corpuscle, and Pacinian corpuscle and the subcellular distribution of Piezo2 within them. Across all three end organs, Piezo2 is restricted to the sensory axon membrane, including axon protrusions that extend from the axon body. These protrusions, which are numerous and elaborate extensively within the end organs, tether the axon to resident non-neuronal cells via adherens junctions. These findings support a unified model for dynamic touch in which mechanical stimuli stretch hundreds to thousands of axon protrusions across an end organ, opening proximal, axonal Piezo2 channels and exciting the neuron.This dataset contains the FIB-SEM data of a double-innervated Meissner corpuscle from the forepaw of a 3-week-old C57BL/6J mouse.Protocol: Samples were dissected and drop fixed in glutaraldehyde and paraformaldehyde, and then osmicated with osmium tetroxide and potassium ferrocyanide, followed by osmium tetroxide only. Samples were subsequently stained with uranyl acetate and samarium chloride. Samples were dehydrated with an ethanol series followed by anhydrous acetone, infiltrated with Durcupan resin, and cured at 60°C.Contributions: Sample provided by Annie Handler (Harvard Medical School/HHMI) and Qiyu Zhang (Harvard Medical School/HHMI), prepared for imaging by Song Pang (HHMI/Janelia, currently at Yale School of Medicine), imaged by Song Pang and C. Shan Xu (HHMI/Janelia, currently at Yale School of Medicine), post data registration by C. Shan Xu, global image alignment and processing by Annie Handler and Qiyu Zhang, automatic segmentation by Tri M. Nguyen (Harvard Medical School) under the supervision of Wei-Chung Allen Lee (Harvard Medical School), ground truth annotation by Rebecca Plumb, Brianna Sanchez, Karyl Ashjian, Aria Shotland, Bartianna Brown, Madiha Kabeer, Nusrat Africawala, Stuart Cattel, Annie Handler, and Qiyu Zhang (all Harvard Medical School/HHMI), and segmentation proofreading by Annie Handler, Qiyu Zhang, and Michael Nolan-Tamariz (Harvard Medical School/HHMI).Acquisition ID: jrc_mus-meissner-corpuscle-2Voxel size (nm): 6 x 6 x 6 (x, y, z)Data dimensions (µm): 74.1 x 55.1 x 69.6 (x, y, z)Scanning speed (MHz): 1Dataset URL (Redirect): https://data.janelia.org/GCyjJVisualization Website: https://openorganelle.janelia.org/datasets/jrc_mus-meissner-corpuscle-2Publication: Handler et al., 2023</p
Segmentation of isotropic 3D electron microscopy (FIB-SEM) data of mouse single-innervated Meissner corpuscle (jrc_mus-meissner-corpuscle-1)
No full textSample: Single-innervated Meissner corpuscle from the forepaw of a 3-week-old C57BL/6J WT mouseSample Description: Across mammalian skin, structurally complex and diverse mechanosensory end organs respond to mechanical stimuli and enable our perception of dynamic, light touch. How forces act on morphologically dissimilar mechanosensory end organs of the skin to gate the requisite mechanotransduction channel Piezo2 and excite mechanosensory neurons is not understood. Here, we report high-resolution reconstructions of the hair follicle lanceolate complex, Meissner corpuscle, and Pacinian corpuscle and the subcellular distribution of Piezo2 within them. Across all three end organs, Piezo2 is restricted to the sensory axon membrane, including axon protrusions that extend from the axon body. These protrusions, which are numerous and elaborate extensively within the end organs, tether the axon to resident non-neuronal cells via adherens junctions. These findings support a unified model for dynamic touch in which mechanical stimuli stretch hundreds to thousands of axon protrusions across an end organ, opening proximal, axonal Piezo2 channels and exciting the neuron.This dataset contains manually proofread automatic segmentation of the FIB-SEM dataset in jrc_mus-meissner-corpuscle-1.Protocol: Samples were dissected and drop fixed in glutaraldehyde and paraformaldehyde, and then osmicated with osmium tetroxide and potassium ferrocyanide, followed by osmium tetroxide only. Samples were subsequently stained with uranyl acetate and samarium chloride. Samples were dehydrated with an ethanol series followed by anhydrous acetone, infiltrated with Durcupan resin, and cured at 60°C.Contributions: Sample provided by Annie Handler (Harvard Medical School/HHMI) and Qiyu Zhang (Harvard Medical School/HHMI), prepared for imaging by Song Pang (HHMI/Janelia, currently at Yale School of Medicine), imaged by Song Pang and C. Shan Xu (HHMI/Janelia, currently at Yale School of Medicine), post data registration by C. Shan Xu, global image alignment and processing by Annie Handler and Qiyu Zhang, automatic segmentation by Tri M. Nguyen (Harvard Medical School) under the supervision of Wei-Chung Allen Lee (Harvard Medical School), ground truth annotation by Rebecca Plumb, Brianna Sanchez, Karyl Ashjian, Aria Shotland, Bartianna Brown, Madiha Kabeer, Nusrat Africawala, Stuart Cattel, Annie Handler, and Qiyu Zhang (all Harvard Medical School/HHMI), and segmentation proofreading by Annie Handler, Qiyu Zhang, and Michael Nolan-Tamariz (Harvard Medical School/HHMI).Acquisition ID: jrc_mus-meissner-corpuscle-1Voxel size (nm): 6 x 6 x 6 (x, y, z)Data dimensions (µm): 36.7 x 45.3 x 57.2 (x, y, z)Scanning speed (MHz): 1Dataset URL (Redirect): https://data.janelia.org/fnQYKEM DOI: https://doi.org/10.25378/janelia.23969070Visualization Website: https://openorganelle.janelia.org/datasets/jrc_mus-meissner-corpuscle-1Publication: Handler et al., 2023</p
Meissner masses in the gCFL phase of QCD
No full textAbstractWe calculate the Meissner masses of gluons in neutral three-flavor color superconducting matter for finite strange quark mass. In the CFL phase the Meissner masses are slowly varying function of the strange quark mass. For large strange quark mass, in the so-called gCFL phase, the Meissner masses of gluons with colors a=1,2 become imaginary, indicating an instability
- …
