1,721,150 research outputs found
Vitamin K and cardiovascular calcification in CKD : is patient supplementation on the horizon?
No full textThe vitamin K-dependent proteins (VKDPs) matrix Gla protein and osteocalcin protect from cardiovascular calcifications and bone fractures. A vitamin K recycling system maintains sufficient vitamin K levels for activation of VKDPs through γ-glutamyl carboxylase (GGCX). Kaesler et al. demonstrate that uremia per se can interfere with GGCX activity, contributing to vitamin K deficiency in chronic kidney disease and opening the path to the clinical use of vitamin K, currently tested in randomized trials
L’Utopia conservatrice della Resistenza : Mistrà e il tracollo di Bisanzio
No full textSi è esposta una valutazione del ruolo di Mistrà nell'ultimo periodo dell'Impero bizantino prima della caduta di Costantinopoli nel 1453, affrontando sia la produzione artistica conservata tuttora in loco sia il ruolo di Gemistio Pletone e della sua filosofia nel panorama culturale del Quattrocento bizantino
Fractures in chronic kidney disease : neglected, common, and associated with sickness and death
Full text linkBone fractures in dialysis patients have been poorly studied in the past. Tentori et al. partially fill this gap, assessing the incidence of post-fracture morbidity and mortality in patients of the Dialysis Outcomes and Practice Patterns Study (DOPPS). A high frequency of fractures and increased adverse outcomes following a fracture were observed. The nephrology community should pay more attention to bone fractures in dialysis patients © 2013 International Society of Nephrology
VERTEBRAL FRACTURES IN PATIENTS ON DIALYSIS: A CLINICALLY RELEVANT PROBLEM WITH INSUFFICIENT INVESTIGATION
No full textSir,
Chronic kidney disease mineral and bone disorder (CKD-MBD), previously denominated renal osteodystrophy [1], is a major clinical problem, with increasing prevalence and adverse outcomes, including high bone turnover associated with secondary hyperparathyroidism, low bone turnover or adynamic bone disease, cardiovascular calcifications and bone fractures. The impact of such outcomes on patient morbidity and mortality has not been fully elucidated. We would like to point out a poorly investigated subject, which we feel is of great clinical importance: .
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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