323,567 research outputs found

    Il caso Lutsenko davanti alla Corte europea dei diritti dell'Uomo

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    Pubblichiamo un breve resoconto dell'udienza tenutasi il 17 aprile 2012 davanti alla Corte europea dei diritti dell'uomo, relativa al procedimento "Lutsenko c. Ucraina". La vicenda riguarda l'ex ministro dell'Interno e attuale leader dell'opposizione in Ucraina, detenuto dal dicembre 2010 per alcuni episodi di abuso di ufficio. Il ricorrente lamenta di essere vittima di repressione politica e chiede che la Corte riconosca la violazione dell'art. 5 Cedu (diritto alla libertà ed alla sicurezza) e la violazione dell'art. 18 Cedu (in materia di tassatività delle restrizioni dei diritti sanciti dalla Cedu), quest'ultima fino ad oggi pronunciata in un unico caso

    Strumok stream cipher: Specification and basic properties

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    STRUMOK is a word-oriented additive stream cipher, where a word in the specification is chosen to be 64 bits. STRUMOK cipher uses some basic design principles from the stream cipher SNOW 2.0. STRUMOK aims at improving SNOW 2.0 both from the security and from the efficiency points of view. Most notably, it uses a more productive keystream generation procedure

    Diffusive author(s), cohesive author: Analysis of S/N (1994)

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    This study indicates the ways in which various aspects of the author(s) are brought forth in Dumb type’s performance art, the S/N production. Previous research has suggested a non-hierarchical organization of Dumb type and the absence of a “privileged author” in Dumb type’s collaborative work, S/N. However, the results that I have investigated from member’s interviews on the creative process of S/N along with my analysis of the recorded images of S/N, indicate a different aspect of the author(s). First, S/N was created through, so to speak, the collective ideas of the members of Dumb type. Further, S/N has at least nine quotations from previous performances, installations, and printed writings, besides the work-in-progress technique. Explicating one of the “author functions” as given by Michel Foucault, each text has plural subjects of the author. However, it has been revealed from members’ interviews that Teiji Furuhashi had a decision-making role in selecting the members’ ideas within the performance. Since then, S/N has had plural subjects of creation; however, Furuhashi is one of the subjects of creation along with the “privileged author.” S/N has plural authors (diffusive authors) yet at the same time, it has a “privileged author,” Teiji Furuhashi (cohesive author)

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Single nucleotide polymorphisms in the human ATP7B gene modify the properties of the ATP7B protein

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    Single nucleotide polymorphisms (SNPs) are the largest source of sequence variation in the human genome. However, their functional significance is not well understood. We show that SNPs in the Wilson disease gene, ATP7B, that produce amino-acid substitutions K832R and R952K, modulate ATP7B properties in vitro and influence serum copper (Cu) status in vivo. The presence of R832 is associated with a lower ATP7B abundance and a diminished trafficking in response to elevated Cu. The K832R substitution alters surface exposure of amino acid residues in the actuator domain and increases its conformational flexibility. All SNP-related ATP7B variants (R832/R952, R832/K952, K832/K952, and K832/R952) have Cu-transport activity. However, the activity of ATP7B-K832/K952 is lower compared to other variants. In humans, the presence of K952 is associated with a higher fraction of exchangeable Cu in serum. Thus, SNPs may modulate the properties of ATP7B and the organism Cu status

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Data associated with the publication: Functional screen of Wilson Disease ATP7B variants

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    The current dataset includes the the associated data such as microscopy images, data quantification and detailed visual summaries to the article Functional Screen of Wilson Disease ATP7B Variants Reveals Residual Transport Activities. Calvo, J. S.; Heger, T.; Kabin, E.; Mowrey, W.R.; Del Angel, G.; Ding, W.; Lutsenko, S. Human Mutation, 2025 (1). This investigator-initiated project is funded through an externally sponsored research agreement with Alexion, AstraZeneca Rare Disease (Boston, MA, United States). T.H. was supported by the Boehringer Ingelheim Fonds travel grant, the Lundbeck Foundation, and the Department of Molecular Biology and Genetics, Aarhus University, Denmark

    Author's address:

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    Can archives of audiovisual TV interviews be used to make authors more visible to students, and thereby reduce the learning gap between native and non-native language speakers in college classes? We examined students in a college course who learned about one scholar's ideas through watching an audiovisual TV interview (i.e., visible author format) and about another scholar's ideas through reading a formal text description (i.e., invisible author format). For the invisible author, native language speakers scored significantly higher than the non-native language speakers on a corresponding exam question (i.e., a cognitive measure), generated more words on the exam question (i.e., a motivational measure), and mentioned the author's name more often in answering the exam question (i.e., an affective measure). For the visible author, the groups did not differ on any of these measures. These findings provide evidence for the idea that making the author visible through audiovisual TV interviews can eliminate the learning gap between native and non-native language speakers. 3 Universities around the world serve students who are non-native speakers of th
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