1,721,025 research outputs found

    A CAD System for Developing Chemical Sensor-Based Microsystems with an ISFET-CMOS Compatible Technology

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    A CAD system, which makes use of an ad hoc technology [ISFET/CMNOS (ionsensitive field-effect transistor/complementary metal nitride-oxide semiconductor) technology] for fabricating ISFET-based microsystems, has been developed. This technology combines ISFET fabrication technology and CMOS IC processes. To test it, we designed and built a microsystem consisting of three blocks (sensor, amplifier, and test structures) which allows us to check the electrochemical characteristics of the ISFET-based sensor, to evaluate the response of the microsystem under different measurement conditions, and to extract the parameters for BIOSPICE. The extraction of electrical and chemical parameters necessary to simulate the sensor behavior and to optimize the circuit design represents the basic and fundamental link between design and manufacturing. The CAD system developed can be considered a general purpose tool for designing integrated and ` intelligent` sensing probes based on ISFET sensors. Similar microsystems can be used for any biomedical, environmental and biotechnological applications where slight variations around a static pH value are expected and miniaturization is require

    A Test Chip for ISFET/CMNOS Technology Development

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    The design, fabrication and preliminary characterization of a test aimed at the development of Ion Sensitive Field Effect Transistors coupled with CMNOS (Complementary Metal gate Nitride Oxide Silicon) circuitry is reported. By this technology inexpensive single chemical sensors or arrays and multi-sensors with on-board signal conditioning for environmental and biomedical applications are being developed. The test chip contains three sets of test structures in order to evaluate the chemical sensor performance, to extract the CMNOS process parameters (e.g. SPICE parameters) and to test basic analogue circuit blocks to be used for the on chip interface electronics

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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