1,721,221 research outputs found
Dementias and cognitive disorders: New insights and approaches
No full textThis Special Issue of Mechanisms of Ageing and Development
is based upon scientific contributions presented to the first
Congress of Italian Society for the Study of Dementias and
Cognitive Disorders (SIDeC), held in Milan on 21 and 22 May
2004. It also includes papers prepared by other groups, to
complete a broader approach to the topic.
TheSpecial Issue,liketheCongress, is aimedatdiscussingnew
insightsonclinicalandpharmacological researchincognitivedisorders
and dementia, with particular emphasis on early diagnosis
of dementia disorders, identification of biological markers and
perspective of different therapeutic approaches, including both
pharmacological and non-pharmacological interventions.
The Special Issue is dedicated to the memory of Virgilio
Gallai, professor of neurology at the University of Perugia, who
founded SIDeC and dedicated the latter part of his life to the
creation of this dynamic, interdisciplinary society aimed at
favouring scientific collaboration among researchers and other
professionals involved in the field of dementias. Although some
of the papers included within the Special Issue, such as those
dealing with early diagnosis, fall outside the normal scope of
Mechanisms of Ageing and Development, they have been
included, with the agreement of the journal Editors, within this
collection which aims at building translational links between
basic and clinical sciences, in order to improve prevention and
effective treatment in this most important area.
We thank the more than 250 participants in the first SIDeC
Congress for creating the background to a highly successful
exchange of ideas and the authors of this Special Issue for their
contributions to developing the debate further
IX Congresso Sindem: Italian Association for the study of Dementia linked to the Italian Neurological Society (SIN)
No full textAbstracts of the IX Congresso SindemItalian Association for the study of Dementia linked to the Italian Neurological Society (SIN)Firenze, Palazzo dei Congressi, Villa Vittoria March 13-15, 2014Comitato Scientifico: Vincenzo Bonavita, Alessandro Padovani, Amalia Bruni, Leonardo Pantoni, Carlo Caltagirone, Lucilla Parnetti, Francesca Clerici, Daniela Perani, Monica Di Luca, Sandro Sorbi, Gianluigi Forloni, Francesco Tagliavini, Giovanni Frisoni, Marilu Gorno Tempini, Claudio Mariani, Annalena Venneri, Massimo Musicco
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
L'educazione socio-emotiva a scuola: una ricerca europea per promuovere la qualità dei processi inclusivi
No full textVariations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Le emozioni nei contesti individuali e sociali
No full textIl volume costituisce un affondo interdisciplinare al tema delle emozioni. La visione di insieme che emerge dai diversi contributi scientifici proposti e che costituiscono il libro, dall’ambito medico, a quello delle scienze umane, sociali ed economiche, è uno sguardo d’insieme e un’apertura a dimensioni specifiche d’indagine su un tema complesso che investe profondamente l’essenza stessa dell’essere umano, definendo quello stesso contesto relazionale in cui le emozioni nascono e infine assumono senso
Role of CSF biomarkers in the diagnosis of prodromal Alzheimer’s disease
No full text Alzheimer’s disease (AD) core biomarkers (Aβ1-42, total tau and phosphorylated tau) have proven to be useful in the clinical practice to evaluate patients with mild cognitive impairment in order to predict progression to Alzheimer’s disease. Multicenter studies have shown an good overall performance of Aβ1-42, total tau and phosphorylated tau in the diagnosis of early AD; however, they also evidenced some possible weakness in terms of variability among centers, which generates some concern about their use in routine clinical practice. Therefore, the need for a joint effort of academia, companies and government agencies is evident. In this article we will provide the state of art of AD biomarkers application for the diagnosis of early AD, also describing some of the most promising new putative biomarkers currently studied. The final aim is to introduce a panel of AD biomarkers that is able to describe the preclinical phases of AD, as fully as possible paving the way to a routine early diagnosis in view of treatment by means of disease-modifying drugs. </jats:p
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